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ChemicalBook >> CAS DataBase List >>3':5'-Cyclic-nucleotide 5'-nucleotidohydrolase

3':5'-Cyclic-nucleotide 5'-nucleotidohydrolase

3':5'-Cyclic-nucleotide 5'-nucleotidohydrolase Structure
3':5'-Cyclic-nucleotide 5'-nucleotidohydrolase structure
CAS No.
9040-59-9
Chemical Name:
3':5'-Cyclic-nucleotide 5'-nucleotidohydrolase
Synonyms
PDE 3B;EC 3.1.4.17;Phosphodiesterase 3B;(4-Nitrobenzyl)arsonic acid;Phosphodiesterasefrombovinebrain;Phosphodiesterase 3B, Recombinant;3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE;PHOSPHODIESTERASE 3':5'-CYCLIC NUCLEOTIDE;Phosphodiesterase, cyclic 3',5'-nucleotide;Phosphodiesterase 3A from Human, Recombinant
CBNumber:
CB2437361
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD00131864
MOL File:
Mol file
Last updated:2026-09-12 18:51:18
Request For Quotation

3':5'-Cyclic-nucleotide 5'-nucleotidohydrolase Properties

storage temp. -20°C
form lyophilized powder
biological source bovine heart
Specific Activity 1-5units/mg protein (without added calmodulin)
EWG's Food Scores 1
UNSPSC Code 12352204
NACRES NA.54

SAFETY

Risk and Safety Statements

PPE Eyeshields, Gloves, type N95 (US)
WGK Germany  3
Storage Class 11 - Combustible Solids

3':5'-Cyclic-nucleotide 5'-nucleotidohydrolase price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P9529 Phosphodiesterase, 3′,5′-cyclic-nucleotide-specific from bovine brain 15-30?units/mg protein (in the presence of 0.03 mM Ca2+ and a saturating level (10 units per ml) of calmodulin (P2277)), lyophilized powder 9040-59-9 1unit $471 2022-05-15 Buy
Usbiological 526792 PDE3B Purifiedbyimmunoaffinitychromatography. 100ul $736 2026-06-03 Buy
Usbiological 526792 PDE3B Purifiedbyimmunoaffinitychromatography. 200ul $944 2026-06-03 Buy
American Custom Chemicals Corporation ENZ0000358 3',5'-CYCLIC-NUCLEOTIDE-5'-NUCLEOTIDOHYDROLASE 95.00% 9040-59-9 5MG $500.81 2021-12-16 Buy
Product number Packaging Price Buy
P9529 1unit $471 Buy
526792 100ul $736 Buy
526792 200ul $944 Buy
ENZ0000358 5MG $500.81 Buy

3':5'-Cyclic-nucleotide 5'-nucleotidohydrolase Chemical Properties,Uses,Production

Uses

For use in calmodulin (P 0270) assay. Activity is reduced to <50% without calmodulin present.

Uses

Phosphodiesterase, 3′,5′-cyclic-nucleotide-specific from bovine brain has been used to assay the protein activator, calmodulin and in in vitro adenylate cyclase assay.

General Description

Phosphodiesterase (PDE1) exists in two isoforms -PDE1A2 and PDE1B1. The enzyme has a role in the complex interaction between cyclic nucleotides and Ca2+ second-messenger systems.

Biochem/physiol Actions

Hydrolyzes the 3′,5′-phosphodiester bond in cyclic nucleotide monophosphates, such as cAMP and cGMP, to the corresponding nucleotide 5′-monophosphate.

Clinical Use

Phosphodiesterase-3 (PDE3) is an enzyme responsible for degradation of cAMP to AMP in platelets and blood vessels. Selective cAMP PDE3 inhibitors, such as dipyridamole and cilostazol , inhibit the degradation of cAMP, thereby increasing cellular concentration of cAMP and leading to inhibition of platelet aggregation and vasodilation.

3':5'-Cyclic-nucleotide 5'-nucleotidohydrolase Preparation Products And Raw materials

Raw materials

Preparation Products

3':5'-Cyclic-nucleotide 5'-nucleotidohydrolase Suppliers

Global( 26)Suppliers
Supplier Tel Email Country ProdList Advantage
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85526065 13308475853 ivy@hnhbsj.com China 7236 62
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Guangzhou Tomums Life Science Co., Ltd. 020-31155029 18902330969 sales@tomums.cn China 4688 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44871 58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 029-029-029-81148696 18161915376 1027@dideu.com China 9989 58
Shanghai Huzhen Industrial Co., LTD 021-60345367 13916550749 sales@shzbio.com China 9965 58
Shanghai Yingxin laboratory equipment Co., Ltd 021-021-59178156 15300768757 359382369@qq.com China 10667 58
Shanghai Guchen Biotechnology Co., LTD 021-34675735 19147740836 1986399151@qq.com China 9839 58
Chengdu Peter-like Biotechnology Co., Ltd. 028-81700200 13308200041 2851167782@qq.com China 10763 58
Shanghai meikai technology co., ltd 021-68689288 15300790979 info@mkbio.com.cn China 9988 58
Supplier Advantage
Hunan Hui Bai Shi Biotechnology Co., Ltd. 62
Sigma-Aldrich 80
Guangzhou Tomums Life Science Co., Ltd. 58
Energy Chemical 58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 58
Shanghai Huzhen Industrial Co., LTD 58
Shanghai Yingxin laboratory equipment Co., Ltd 58
Shanghai Guchen Biotechnology Co., LTD 58
Chengdu Peter-like Biotechnology Co., Ltd. 58
Shanghai meikai technology co., ltd 58

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3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE phosphodiesterase 3':5'-cyclic*nucleotide crude C Phosphodiesterase, cyclic 3',5'-nucleotide PHOSPHODIESTERASE 3':5'-CYCLIC*NUCLEOTID E FROM BOVI PHOSPHODIESTERASE 3':5'-CYCLIC*NUCLEOTID E CRUDE COM Phosphodiesterasefrombovinebrain 3',5'-cyclic-nucleotide 5'-nucleotidohydrolase from bovine brain phosphodiesterase, 3',5'-cyclic-nucleotide-specific from bovine brain CYCLIC 3'',5''-NUCLEOTIDE PHOSPHODIESTERASE (FROM BEEF HEART) phosphodiesterase, 3',5'-cyclic-nucleotide-specific PDE, 3μ,5μ-Cyclic-nucleotide 5μ-nucleotidohydrolase from porcine brain Phosphodiesterase, 3μ,5μ-Cyclic Nucleotide, Activator-deficient from porcine brain PDE, 3μ,5μ-Cyclic-nucleotide 5μ-nucleotidohydrolase from bovine brain PDE, 3μ,5μ-Cyclic-nucleotide 5μ-nucleotidohydrolase from bovine heart Phosphodiesterase 3μ,5μ-Cyclic Nucleotide Activator-deficient from bovine heart PHOSPHODIESTERASE 3':5'-CYCLIC NUCLEOTIDE EC 3.1.4.17 PDE 3B Phosphodiesterase 3B Phosphodiesterase 3B, Recombinant Native Bovine Phosphodiesterase 3,5-Cyclic Nucleotide Activator-deficient Native Bovine Phosphodiesterase, 3,5-cyclic-nucleotide-specific Native Porcine Phosphodiesterase, 3,5-Cyclic Nucleotide, Activator-deficient Phosphodiesterase 3A from Human, Recombinant Phosphodiesterase, 3',5'-cyclic-nucleotide-specific from bovine brain 15-30 units/mg protein (in the presence of 0.03 mM Ca2+ and a saturating level (10 units per ml) of calmodulin (P2277)), lyophilized powder (4-Nitrobenzyl)arsonic acid 3':5'-Cyclic-nucleotide 5'-nucleotidohydrolase 9040-59-9 BioChemical Cell Signaling and Neuroscience Cell Biology Cyclic Nucleotide Metabolism G Proteins and Cyclic Nucleotides Enzymes