ChemicalBook >> CAS DataBase List >>6,6'-Dihydroxy-5,5'-dimethoxy-[1,1'-biphenyl]-3,3'-dicarboxaldehyde

6,6'-Dihydroxy-5,5'-dimethoxy-[1,1'-biphenyl]-3,3'-dicarboxaldehyde

6,6'-Dihydroxy-5,5'-dimethoxy-[1,1'-biphenyl]-3,3'-dicarboxaldehyde structure

CAS No.: 2092-49-1

Chemical Name:: 6,6'-Dihydroxy-5,5'-dimethoxy-[1,1'-biphenyl]-3,3'-dicarboxaldehyde

Synonyms: DIVANILLIN;Dehydrovanillin;5,5'-Bivanillin;dehydrodivanillin;6 6'-DIHYDROXY-5 5'-DIMETHOXY-(1 1'-BIP&;6,6'-dihydroxy-5,5'-dimethoxy-(1,1'-biphen -yl)-3;5,5'-Dimethoxy-6,6'-dihydroxybiphenyl-3,3'-dicarbaldehyde;6,6'-dihydroxy-5,5'-dimethoxybiphenyl-3,3'-dicarbaldehyde;3,3'-Biphenyldicarboxaldehyde, 6,6'-dihydroxy-5,5'-dimethoxy-;6,6'-Dihydroxy-5,5'-dimethoxy-1,1'-biphenyl-3,3'-dicarbaldehyde

CBNumber:: CB2445663

Molecular Formula:: C16H14O6

Molecular Weight:: 302.28

MDL Number:: MFCD00156888

MOL File:: 2092-49-1.mol

MSDS File:: SDS

Last updated:2026-09-12 18:51:18

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6,6'-Dihydroxy-5,5'-dimethoxy-[1,1'-biphenyl]-3,3'-dicarboxaldehyde Properties

Melting point	315 °C(lit.)
Boiling point	486.3±45.0 °C(Predicted)
Density	1.356±0.06 g/cm3(Predicted)
FEMA	4107 \| DIVANILLIN
FLAVIS Number	05.221 \| 6,6'-Dihydroxy-5,5'-dimethoxy-biphenyl-3,3'-dicarbaldehyde
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	DMSO (Slightly), Ethanol (Slightly, Heated), Methanol (Slightly)
form	Solid
pka	6.62±0.48(Predicted)
color	Dark Brown to Very Dark Gray
Odor	at 100.00 %. fruity vanilla
Odor Type	vanilla
JECFA Number	1881
LogP	1.57
Substances Added to Food (formerly EAFUS)	DIVANILLIN
FDA UNII	29PYY1H4BT

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H319-H302
Precautionary statements	P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501
Hazard Codes	Xn
Risk Statements	22-36
Safety Statements	26-36

6,6'-Dihydroxy-5,5'-dimethoxy-[1,1'-biphenyl]-3,3'-dicarboxaldehyde price More Price(32)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	FD71561	6,6'-Dihydroxy-5,5'-dimethoxy- [1,1'-biphenyl]-3,3'-dicarboxaldehyde	2092-49-1	0.1g	$181.4	2026-06-04	Buy
Biosynth	FD71561	6,6'-Dihydroxy-5,5'-dimethoxy- [1,1'-biphenyl]-3,3'-dicarboxaldehyde	2092-49-1	0.25g	$272.1	2026-06-04	Buy
Biosynth	FD71561	6,6'-Dihydroxy-5,5'-dimethoxy- [1,1'-biphenyl]-3,3'-dicarboxaldehyde	2092-49-1	0.5g	$362.81	2026-06-04	Buy
Biosynth	FD71561	6,6'-Dihydroxy-5,5'-dimethoxy- [1,1'-biphenyl]-3,3'-dicarboxaldehyde	2092-49-1	1g	$453.51	2026-06-04	Buy
Biosynth	FD71561	6,6'-Dihydroxy-5,5'-dimethoxy- [1,1'-biphenyl]-3,3'-dicarboxaldehyde	2092-49-1	2g	$816.34	2026-06-04	Buy

Product number	Packaging	Price	Buy
FD71561	0.1g	$181.4	Buy
FD71561	0.25g	$272.1	Buy
FD71561	0.5g	$362.81	Buy
FD71561	1g	$453.51	Buy
FD71561	2g	$816.34	Buy

6,6'-Dihydroxy-5,5'-dimethoxy-[1,1'-biphenyl]-3,3'-dicarboxaldehyde Chemical Properties, Uses, Production

Chemical Properties

White solid; fruity vanilla aroma.

Uses

Dehydrodivanillin is used as a reactant in the preparation of antioxidant phenolic diaryl hydrazones as antiangiogenic agents for atherosclerosis therapy. Also used as a taste enhancer.

Synthesis

121-33-5

2092-49-1

General procedure for the synthesis of 6,6'-dihydroxy-5,5'-dimethoxy-(1,1'-biphenyl)-3,3'-dicarboxaldehyde from vanillin: 5 g of vanillin (33 mmol, purchased from Wako Pure Chemical Industries, Ltd.) was dissolved in 200 ml of ion-exchanger water preheated to 80 °C. To this solution, 200 mg (0.72 mmol) of iron sulfate (purchased from Wako Pure Chemical Industries, Ltd.) and 5 g (19 mmol) of potassium peroxydisulfate (purchased from Wako Pure Chemical Industries, Ltd.) were sequentially added, followed by heating and refluxing for 1 hr at 120 °C. Upon completion of the reaction, unreacted vanillin was removed by thermal filtration to afford intermediate (a1) in 97% yield.

References

[1] Bioorganic and Medicinal Chemistry, 2005, vol. 13, # 7, p. 2537 - 2546
[2] European Journal of Organic Chemistry, 2013, # 1, p. 173 - 179
[3] Patent: JP2017/14122, 2017, A. Location in patent: Paragraph 0051
[4] Journal of Molecular Catalysis B: Enzymatic, 2016, vol. 125, p. 34 - 41
[5] Journal of Medicinal Chemistry, 2008, vol. 51, # 11, p. 3171 - 3181

6,6'-Dihydroxy-5,5'-dimethoxy-[1,1'-biphenyl]-3,3'-dicarboxaldehyde Preparation Products And Raw materials

Raw materials

Vanillin Potassium persulfate Ferrous sulfate

Preparation Products

5-Iodovanillin

6,6'-Dihydroxy-5,5'-dimethoxy-[1,1'-biphenyl]-3,3'-dicarboxaldehyde Suppliers

Global Suppliers ( 56)

Supplier	Tel	Email	Country	ProdList	Advantage
Changzhou Wanyao Biotechnology Co., Ltd.	0519-89185693 15312551983	2410037592@qq.com	China	278	55
Nanjing JinruiJiuAn Biotechnology Co., Ltd.	025-58196018 800028039	sales@fartop.net	China	2227	55
BeiJing TOP Science Bio-Technology Co., Ltd.	+86-13439059536 +86-15201677815	2638315663@qq.com	China	292	58
Finetech Industry Limited	027-87465837 19945049750	sales@finetechnology-ind.com	China	9331	58
Hangzhou J&H Chemical Co., Ltd.	0571-87396432	sales@jhechem.com	China	14905	59
Nanjing River Chemical Co., Ltd.	13951936332 18305166317	info@serpharm.com	China	493	55
skychemical Co.Ltd	021-20960837,QQ1332204249	sales@skychemical.com	China	3338	55
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Aikon International Limited	025-58859352 13913916777	dt3@aikonchem.com	China	15490	58

Supplier	Advantage
Changzhou Wanyao Biotechnology Co., Ltd.	55
Nanjing JinruiJiuAn Biotechnology Co., Ltd.	55
BeiJing TOP Science Bio-Technology Co., Ltd.	58
Finetech Industry Limited	58
Hangzhou J&H Chemical Co., Ltd.	59
Nanjing River Chemical Co., Ltd.	55
skychemical Co.Ltd	55
Shanghai YuanYe Biotechnology Co., Ltd.	60
Amadis Chemical Company Limited	58
Aikon International Limited	58

View Latest Price from 6,6'-Dihydroxy-5,5'-dimethoxy-[1,1'-biphenyl]-3,3'-dicarboxaldehyde manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-14	6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE 2092-49-1	$1.00	1KG	90%-99.9%	500kg	Career Henan Chemical Co
	2019-07-10	6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE 2092-49-1	$1.00	1KG	90%-99.9%	500kg	Career Henan Chemical Co

6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE
2092-49-1
$1.00
90%-99.9%
Career Henan Chemical Co

6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE
2092-49-1
$1.00
90%-99.9%
Career Henan Chemical Co

6,6'-Dihydroxy-5,5'-dimethoxy-[1,1'-biphenyl]-3,3'-dicarboxaldehyde Spectrum

6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE(2092-49-1)¹HNMR

2092-49-1 (6,6'-Dihydroxy-5,5'-dimethoxy-[1,1'-biphenyl]-3,3'-dicarboxaldehyde) Related Search:

Vanillin ISOEUGENOL 3-Hydroxy-2-methyl-4H-pyran-4-one 3-(5-carboxy-2-hydroxy-3-methoxy-phenyl)-4-hydroxy-5-methoxy-benzoic a cid DIMETHOXY DI-p-CRESOL

MFCD01880938

1of2

6,6'-dihydroxy-5,5'-dimethoxy-(1,1'-biphen -yl)-3 6 6'-DIHYDROXY-5 5'-DIMETHOXY-(1 1'-BIP& dehydrodivanillin 6,6'-dihydroxy-5,5'-dimethoxybiphenyl-3,3'-dicarbaldehyde 2,2'-Dihydroxy-3,3'-dimethoxy-1,1'-biphenyl-5,5'-dicarbaldehyde 5,5'-Bivanillin 5,5'-Dimethoxy-6,6'-dihydroxybiphenyl-3,3'-dicarbaldehyde 6,6'-Dihydroxy-5,5'-dimethoxy-1,1'-biphenyl-3,3'-dicarbaldehyde [1,1'-Biphenyl]-3,3'-dicarboxaldehyde, 6,6'-dihydroxy-5,5'-dimethoxy- 3,3-Biphenyldicarboxaldehyde, 6,6-dihydroxy-5,5-diMethoxy- (8CI) Dehydrovanillin (1,1'-Biphenyl)-3,3'-dicarboxaldehyde, 6,6'-dihydroxy-5,5'-dimethoxy- (9CI) 3-(5-formyl-2-hydroxy-3-methoxy-phenyl)-4-hydroxy-5-methoxy-benzaldehyde 3-(5-formyl-2-hydroxy-3-methoxyphenyl)-4-hydroxy-5-methoxybenzaldehyde 3,3'-Biphenyldicarboxaldehyde, 6,6'-dihydroxy-5,5'-dimethoxy- 3,3'-Biphenyldicarboxaldehyde, 6,6'-dihydroxy-5,5'-dimethoxy- (8 4-hydroxy-3-(2-hydroxy-5-methanoyl-3-methoxy-phenyl)-5-methoxy-benzaldehyde 6,6'-dihydroxy-5,5'-dimethoxy-[1,1'-biphenyl]-3,3'-dicarbaldehyde DIVANILLIN 6,6'-Dihydroxy-5,5'-dimethoxy-[1,1'-biphenyl]-3,3'-dicarboxaldehyde 2092-49-1 HOC6H2OCH3CHO2