ChemicalBook >> CAS DataBase List >>6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE

6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE

6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE structure

CAS No.: 2092-49-1

Chemical Name:: 6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE

Synonyms: DIVANILLIN;5,5'-Bivanillin;Dehydrovanillin;dehydrodivanillin;6 6'-DIHYDROXY-5 5'-DIMETHOXY-(1 1'-BIP&;6,6'-dihydroxy-5,5'-dimethoxy-(1,1'-biphen -yl)-3;5,5'-Dimethoxy-6,6'-dihydroxybiphenyl-3,3'-dicarbaldehyde;6,6'-dihydroxy-5,5'-dimethoxybiphenyl-3,3'-dicarbaldehyde;3,3'-Biphenyldicarboxaldehyde, 6,6'-dihydroxy-5,5'-dimethoxy-;6,6'-Dihydroxy-5,5'-dimethoxy-1,1'-biphenyl-3,3'-dicarbaldehyde

CBNumber:: CB2445663

Molecular Formula:: C16H14O6

Molecular Weight:: 302.28

MDL Number:: MFCD00156888

MOL File:: 2092-49-1.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:47

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6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE Properties

Melting point	315 °C(lit.)
Boiling point	486.3±45.0 °C(Predicted)
Density	1.356±0.06 g/cm3(Predicted)
FEMA	4107 \| DIVANILLIN
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	DMSO (Slightly), Ethanol (Slightly, Heated), Methanol (Slightly)
form	Solid
pka	6.62±0.48(Predicted)
color	Dark Brown to Very Dark Gray
Odor	at 100.00 %. fruity vanilla
Odor Type	vanilla
JECFA Number	1881
LogP	1.57
Substances Added to Food (formerly EAFUS)	DIVANILLIN
FDA UNII	29PYY1H4BT

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H319-H302
Precautionary statements	P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501
Hazard Codes	Xn
Risk Statements	22-36
Safety Statements	26-36

6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE price More Price(18)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	D233040	Dehydrodivanillin(~90%,containsupto10%unknowninorganics)	2092-49-1	500mg	$90	2021-12-16	Buy
Usbiological	446024	Dehydrodivanillin	2092-49-1	100mg	$312	2021-12-16	Buy
Biosynth Carbosynth	FD71561	6,6′-Dihydroxy-5,5′-dimethoxy-[1,1′-biphenyl]-3,3′-dicarboxaldehyde	2092-49-1	5G	$450	2021-12-16	Buy
Matrix Scientific	157259	6,6'-Dihydroxy-5,5'-dimethoxybiphenyl-3,3'-dicarbaldehyde	2092-49-1	1g	$165	2021-12-16	Buy
Biosynth Carbosynth	FD71561	6,6′-Dihydroxy-5,5′-dimethoxy-[1,1′-biphenyl]-3,3′-dicarboxaldehyde	2092-49-1	2g	$260	2021-12-16	Buy

Product number	Packaging	Price	Buy
D233040	500mg	$90	Buy
446024	100mg	$312	Buy
FD71561	5G	$450	Buy
157259	1g	$165	Buy
FD71561	2g	$260	Buy

6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE Chemical Properties,Uses,Production

Chemical Properties

White solid; fruity vanilla aroma.

Uses

Dehydrodivanillin is used as a reactant in the preparation of antioxidant phenolic diaryl hydrazones as antiangiogenic agents for atherosclerosis therapy. Also used as a taste enhancer.

Synthesis

121-33-5

2092-49-1

General procedure for the synthesis of 6,6'-dihydroxy-5,5'-dimethoxy-(1,1'-biphenyl)-3,3'-dicarboxaldehyde from vanillin: 5 g of vanillin (33 mmol, purchased from Wako Pure Chemical Industries, Ltd.) was dissolved in 200 ml of ion-exchanger water preheated to 80 °C. To this solution, 200 mg (0.72 mmol) of iron sulfate (purchased from Wako Pure Chemical Industries, Ltd.) and 5 g (19 mmol) of potassium peroxydisulfate (purchased from Wako Pure Chemical Industries, Ltd.) were sequentially added, followed by heating and refluxing for 1 hr at 120 °C. Upon completion of the reaction, unreacted vanillin was removed by thermal filtration to afford intermediate (a1) in 97% yield.

References

[1] Bioorganic and Medicinal Chemistry, 2005, vol. 13, # 7, p. 2537 - 2546
[2] European Journal of Organic Chemistry, 2013, # 1, p. 173 - 179
[3] Patent: JP2017/14122, 2017, A. Location in patent: Paragraph 0051
[4] Journal of Molecular Catalysis B: Enzymatic, 2016, vol. 125, p. 34 - 41
[5] Journal of Medicinal Chemistry, 2008, vol. 51, # 11, p. 3171 - 3181

6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE Preparation Products And Raw materials

Raw materials

Vanillin Potassium persulfate FERROUS SULFATE

Preparation Products

5-Iodovanillin

6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE Suppliers

Global( 50)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29855	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Finetech Industry Limited	+86-27-8746-5837 +8619945049750	info@finetechnology-ind.com	China	9629	58
Alfa Chemistry	+1-5166625404;	Info@alfa-chemistry.com	United States	20405	58
LEAP CHEM CO., LTD.	+86-852-30606658 19957148339;	market18@leapchem.com	China	24727	58
Changzhou AniKare Pharmatech Co., Ltd.	+86-0519-8359-8696 +8618018249389	sales@anikare.com	China	9945	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+86-18621343501; +undefined18621343501	product@acmec-e.com	China	33338	58
SHANGHAI KEAN TECHNOLOGY CO., LTD.	+8613817748580	cooperation@kean-chem.com	China	40066	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39927	58

Supplier	Advantage
Nanjing ChemLin Chemical Industry Co., Ltd.	60
career henan chemical co	58
BOC Sciences	58
Finetech Industry Limited	58
Alfa Chemistry	58
LEAP CHEM CO., LTD.	58
Changzhou AniKare Pharmatech Co., Ltd.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
SHANGHAI KEAN TECHNOLOGY CO., LTD.	58
Chongqing Chemdad Co., Ltd	58

View Lastest Price from 6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-14	6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE 2092-49-1	US $1.00 / KG	1KG	90%-99.9%	500kg	Career Henan Chemical Co
	2019-07-10	6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE 2092-49-1	US $1.00 / KG	1KG	90%-99.9%	500kg	Career Henan Chemical Co

6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE
2092-49-1
US $1.00 / KG
90%-99.9%
Career Henan Chemical Co

6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE
2092-49-1
US $1.00 / KG
90%-99.9%
Career Henan Chemical Co

6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE Spectrum

6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE(2092-49-1)¹HNMR

2092-49-1(6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE)Related Search:

Vanillin ISOEUGENOL 3-Hydroxy-2-methyl-4H-pyran-4-one

6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE 6,6'-dihydroxy-5,5'-dimethoxy-(1,1'-biphen -yl)-3 6 6'-DIHYDROXY-5 5'-DIMETHOXY-(1 1'-BIP& dehydrodivanillin DIVANILLIN 6,6'-dihydroxy-5,5'-dimethoxybiphenyl-3,3'-dicarbaldehyde 2,2'-Dihydroxy-3,3'-dimethoxy-1,1'-biphenyl-5,5'-dicarbaldehyde 5,5'-Bivanillin 5,5'-Dimethoxy-6,6'-dihydroxybiphenyl-3,3'-dicarbaldehyde 6,6'-Dihydroxy-5,5'-dimethoxy-1,1'-biphenyl-3,3'-dicarbaldehyde [1,1'-Biphenyl]-3,3'-dicarboxaldehyde, 6,6'-dihydroxy-5,5'-dimethoxy- 3,3-Biphenyldicarboxaldehyde, 6,6-dihydroxy-5,5-diMethoxy- (8CI) Dehydrovanillin (1,1'-Biphenyl)-3,3'-dicarboxaldehyde, 6,6'-dihydroxy-5,5'-dimethoxy- (9CI) 3-(5-formyl-2-hydroxy-3-methoxy-phenyl)-4-hydroxy-5-methoxy-benzaldehyde 3-(5-formyl-2-hydroxy-3-methoxyphenyl)-4-hydroxy-5-methoxybenzaldehyde 3,3'-Biphenyldicarboxaldehyde, 6,6'-dihydroxy-5,5'-dimethoxy- 3,3'-Biphenyldicarboxaldehyde, 6,6'-dihydroxy-5,5'-dimethoxy- (8 4-hydroxy-3-(2-hydroxy-5-methanoyl-3-methoxy-phenyl)-5-methoxy-benzaldehyde 6,6'-dihydroxy-5,5'-dimethoxy-[1,1'-biphenyl]-3,3'-dicarbaldehyde 2092-49-1 HOC6H2OCH3CHO2