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Quinine hydrochloride

Quinine hydrochloride structure

CAS No.: 130-89-2

Chemical Name:: Quinine hydrochloride

Synonyms: QUININE HCL;QUININE HCL;QUININE HC;chinimetten;quininemuriate;quininechloride;Quinine Impurity 11;Quinine hydrochlorid;QUININE HYDROCHLORIDE;Quinine HCL & Sulfate

CBNumber:: CB2453521

Molecular Formula:: C20H25ClN2O2

Molecular Weight:: 360.88

MDL Number:: MFCD00078498

MOL File:: 130-89-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-16 07:06:08

Product description	Number	Pack Size	Price
Quinine Hydrochloride ≥99%withTBCasstabilizer	288554	10g	$319
Quinine Hydrochloride ≥99%withTBCasstabilizer	288554	25g	$638
Quinine Hydrochloride ≥99%withTBCasstabilizer	288554	50g	$1027
Quinine Hydrochloride ≥99%withTBCasstabilizer	288554	100g	$1380
Quinine Hydrochloride ≥99%withTBCasstabilizer	288554	500g	$2053
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Quinine hydrochloride Properties

Melting point	158-160 C
Density	1.1206 (rough estimate)
refractive index	1.5400 (estimate)
FEMA	2976 \| QUININE HYDROCHLORIDE
FLAVIS Number	14.011 \| Quinine hydrochloride
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	DMSO (Slightly), Ethanol (1g/1ml), glycerol(1g/7ml), chloroform(1g/1ml)
form	Solid
color	White
Water Solubility	549.7mg/L(25 ºC)
InChIKey	LBSFSRMTJJPTCW-QJLYHTAINA-N
SMILES	C12C=C(C=CC=1N=CC=C2[C@@H](O)[C@]1([H])C[C@]2([H])CCN1C[C@@H]2C=C)OC.Cl \|&1:10,12,15,21,r\|
LogP	3.496 (est)
Substances Added to Food (formerly EAFUS)	QUININE HYDROCHLORIDE
FDA UNII	7CS0WNO31M
EPA Substance Registry System	Cinchonan-9-ol, 6'-methoxy-, hydrochloride (1:1), (8.alpha.,9R)- (130-89-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H319
Precautionary statements	P305+P351+P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-24/25
RIDADR	1544
TSCA	TSCA listed
HazardClass	6.1(b)
PackingGroup	III
HS Code	29392000
Toxicity	cat,LDLo,intravenous,80mg/kg (80mg/kg),Journal of Pharmacology and Experimental Therapeutics. Vol. 30, Pg. 327, 1927.

Quinine hydrochloride price More Price(37)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	288554	Quinine Hydrochloride ≥99%withTBCasstabilizer	130-89-2	10g	$319	2026-06-03	Buy
Usbiological	288554	Quinine Hydrochloride ≥99%withTBCasstabilizer	130-89-2	25g	$638	2026-06-03	Buy
Usbiological	288554	Quinine Hydrochloride ≥99%withTBCasstabilizer	130-89-2	50g	$1027	2026-06-03	Buy
Usbiological	288554	Quinine Hydrochloride ≥99%withTBCasstabilizer	130-89-2	100g	$1380	2026-06-03	Buy
Usbiological	288554	Quinine Hydrochloride ≥99%withTBCasstabilizer	130-89-2	500g	$2053	2026-06-03	Buy

Product number	Packaging	Price	Buy
288554	10g	$319	Buy
288554	25g	$638	Buy
288554	50g	$1027	Buy
288554	100g	$1380	Buy
288554	500g	$2053	Buy

Quinine hydrochloride Chemical Properties,Uses,Production

Detection

Several techniques have been employed to detect quinine hydrochloride (QH), including high-performance liquid chromatography, gas chromatography capillary electrophoresis chemiluminescence, and mass spec trometry. However, these methods are often costly, time-consuming, and involve toxic reagents. Leoriza et al. studied the quinine hydrochloride detection using boron-doped diamond electrodes. The research found that the BDD electrodes demonstrated good selectivity in tonic water with sharp oxidation potentials for QH, confirming their stability for QH detection[1].

Chemical Properties

Quinine hydrochloride is a white, silky, glittering needles; odourless, effloresces when exposed to warm air. Soluble in water, very soluble in ethanol, freely soluble in chloroform, insoluble in ether. Its solutions are neutral or alkaline to litmus. It is an alkaloid derived from the bark of the cinchona tree. Quinine Hydrochloride is used as ingredient of beverages and injection medication.

Uses

Quinine Hydrochloride is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.

Definition

Quinine Hydrochloride is the hydrochloride of a natural substance, quinine, obtained from the bark of various species of Cinchona including Cinchona succirubra, Pavon. (red cinchona); Cinchona officinalis, Linn; Cinchona calizaya, Wenddell; Cinchona ledgeriana, Moens. It is a nature-derived bitter flavoring agent for tonic water, among other beverages.

Biological Activity

Quinine hydrochloride is a displays antimalarial and muscle relaxant properties. Stereoisomer of quinidine; closely related to chloroquine.

Side effects

Quinine hydrochloride (QH), a natural alkaloid found in the bark of the cinchona tree, is commonly used to impart a bitter taste to tonic water, significantly contributing to its flavour profile. Despite its widespread use, QH can be toxic at higher concentrations of 10 μg/mL It can lead to side effects such as headaches, increased body temperature, insomnia, gastrointestinal issues, cinchonism, and, in se vere cases, cardiac arrhythmias[1].

Safety Profile

Poison by ingestion, subcutaneous, intravenous, intramuscular, and intraperitoneal routes. Human systemic effects by intravenous route: convulsions or effect on seizure threshold, muscle contraction or spasticity, and nausea or vomiting. Mutation data reported. Used as a local anesthetic. When heated to decomposition it emits very toxic fumes of NO, and HCI. See also QUININE.

Synthesis

Manufacture of quinine by extraction from Cinchona bark and subsequent purification and synthesis to quinine hydrochloride.

target

Adrenergic Receptor

storage

Store at -20°C

References

[1] Meutya Dwi Leoriza . “Study of quinine hydrochloride detection using boron-doped diamond electrodes.” International Journal of Electrochemical Science 19 10 (2024): Article 100778.
[2] Endriz, John D. “Spectrophotometric Determination of Heroin Hydrochloride, Methapyrilene Hydrochloride, and Quinine Hydrochloride.” Journal of AOAC International 46 1 (1963): 637–641.

Quinine hydrochloride Preparation Products And Raw materials

Raw materials

Cinchona ledgeriana bark Quinine

Preparation Products

Quinine hydrochloride Suppliers

Global( 183)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+86-15350571055	Sibel@chuanghaibio.com	China	8737	58
Hebei Yanxi Chemical Co., Ltd.	+86-17531190177	faithe@yan-xi.com	China	5838	58
Nanjing Deda New Material Technology Co., Ltd	+8613223293093	bella@njdeda.com	China	79	58
Anhui Ruihan Technology Co., Ltd	+undefined17756083858	daisy@anhuiruihan.com	China	954	58
Wuhan Ruichi Technology Co., Ltd	+undefined13545065237	admin@whrchem.com	China	150	58
Chongqing Soarwin Technology Co., Ltd	+86-15790943001	crystal@sorawin.cn	China	419	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21531	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32997	60
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3618	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29766	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Nanjing Deda New Material Technology Co., Ltd	58
Anhui Ruihan Technology Co., Ltd	58
Wuhan Ruichi Technology Co., Ltd	58
Chongqing Soarwin Technology Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58

View Lastest Price from Quinine hydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-15	Quinine HCl 130-89-2	$80.00			10g	TargetMol Chemicals Inc.
2026-06-30	Quinine hydrochloride 130-89-2		1kg	99%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2026-03-20	QUININE HCL 130-89-2	$8.00-10.00	100KG	99%	100 mt	Hebei Chuanghai Biotechnology Co., Ltd

Quinine HCl
130-89-2
$80.00
TargetMol Chemicals Inc.

Quinine hydrochloride
130-89-2
$0.00
99%
Shaanxi Dideu New Materials Co. Ltd

QUININE HCL
130-89-2
$8.00-10.00
99%
Hebei Chuanghai Biotechnology Co., Ltd

Quinine hydrochloride Spectrum

QUININE HCL(130-89-2)¹HNMR QUININE HCL(130-89-2)¹³CNMR QUININE HCL(130-89-2)IR1 QUININE HCL(130-89-2)Raman

130-89-2(Quinine hydrochloride)Related Search:

Quinidine Cinchonidine Quinine sulfate dihydrate Quinine Quinine dihydrochloride

Quinine hydrochloride (8α,9R)-6'-Methoxycinchonan-9-ol/hydrochloric acid,(1:x) N-BENZYLQUININIUM CHLORIDE Quinine QUININE HCL / DIHCL / SULFATE

Quinine HCl medical grade QUININE HCL USP(CRM STANDARD) QUININE HCL NON-KOSHER 6-METHOXYCINCHONINE UREA HYDROCHLORIDE togal

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QUININE HYDROCHLORIDE QUININE MONOHYDROCHLORIDE 6’-methoxy-,monohydrochloride,(8.alpha.,9R)-Cinchonan-9-ol 6’-methoxy-,monohydrochloride,(8-alpha,9r)-cinchonan-9-o 6’-methoxy-,monohydrochloride,(8alpha,9theta)-cinchonan-9-o chinimetten quininechloride quininemuriate Hydrochloric acid quinine Quinine·hydrochloric acid Quinine HCL & Sulfate Cinchonan-9-ol,6'-Methoxy-, hydrochloride (1:1), (8alpha,9R)- (8alpha,9R)-6'-methoxycinchonan-9-ol monohydrochloride QUININE HYDROCHLORIDE 2 H2O Cinchonan-9-ol, 6-methoxy-, monohydrochloride, (8.alpha.,9R)- Cinchonan-9-ol, 6'-methoxy-, monohydrochloride, (8a,9R)- (9CI) Quinine, monohydrochloride (8CI) (R)-[(4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol:hydrochloride Cinchonan-9-ol, 6'-methoxy-, hydrochloride (1:1), (8α,9R)- Quinine Hydrochloride HCL QUININE HCL USP/EP/BP (R)-(6-Methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol hydrochloride Quinine hydrochlorid (R)-[(2S，4S，5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol hydrochloride QUININE HC Quinine Impurity 11 Cyproconazole Impurity 3 QUININE HCL QUININE HCL 130-89-2 C10H24N2O22H2O C20H24N2O2HCl C20H25N2O2Cl