4-(4-(tert-butoxycarbonyl)piperazin-1-yl)benzo[b]thiophene-2-carboxylic acid

CAS No.
1677681-02-5
Chemical Name:
4-(4-(tert-butoxycarbonyl)piperazin-1-yl)benzo[b]thiophene-2-carboxylic acid
Synonyms
Raloxifene Impurity 11;4-(4-(tert-butoxycarbonyl)piperazin-1-yl)benzo[b]thiophene-2-carboxylic acid;1-Piperazinecarboxylic acid, 4-(2-carboxybenzo[b]thien-4-yl)-, 1-(1,1-dimethylethyl) ester
CBNumber:
CB24775003
Molecular Formula:
C18H22N2O4S
Molecular Weight:
362.44
MDL Number:
MFCD29058610
MOL File:
1677681-02-5.mol
Last updated:2026-05-28 00:45:01

4-(4-(tert-butoxycarbonyl)piperazin-1-yl)benzo[b]thiophene-2-carboxylic acid Properties

Boiling point 554.7±50.0 °C(Predicted)
Density 1.312±0.06 g/cm3(Predicted)
pka 3.94±0.30(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335-H302
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501

4-(4-(tert-butoxycarbonyl)piperazin-1-yl)benzo[b]thiophene-2-carboxylic acid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 429022 4-(4-Boc-piperazin-1-yl)benzo[b]thein-2-carboxylate 1677681-02-5 100mg $468 2026-06-03 Buy
Usbiological 429022 4-(4-Boc-piperazin-1-yl)benzo[b]thein-2-carboxylate 1677681-02-5 250mg $927 2026-06-03 Buy
Biosynth CSC68102 4-(4-(tert-Butoxycarbonyl)piperazin-1-yl)benzo[b]thiophene-2-carboxylic acid 1677681-02-5 100mg $326 2026-06-04 Buy
Biosynth CSC68102 4-(4-(tert-Butoxycarbonyl)piperazin-1-yl)benzo[b]thiophene-2-carboxylic acid 1677681-02-5 1g $1038.4 2026-06-04 Buy
aablocks AA01DT9H 4-(4-(tert-Butoxycarbonyl)piperazin-1-yl)benzo[b]thiophene-2-carboxylic acid 95.00% 1677681-02-5 50mg $135 2026-05-29 Buy
Product number Packaging Price Buy
429022 100mg $468 Buy
429022 250mg $927 Buy
CSC68102 100mg $326 Buy
CSC68102 1g $1038.4 Buy
AA01DT9H 50mg $135 Buy

4-(4-(tert-butoxycarbonyl)piperazin-1-yl)benzo[b]thiophene-2-carboxylic acid Chemical Properties, Uses, Production

Uses

4-(4-Boc-piperazin-1-yl)benzo[b]thein-2-carboxylate is an intermediate in the synthesis of Brexpiprazole (B677385).

4-(4-(tert-butoxycarbonyl)piperazin-1-yl)benzo[b]thiophene-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

4-(4-(tert-butoxycarbonyl)piperazin-1-yl)benzo[b]thiophene-2-carboxylic acid Suppliers

Global Suppliers ( 9)
Supplier Tel Email Country ProdList Advantage
Aikon International Limited 025-58851090 13913916777 sales01@aikonchem.com China 15947 58
Jinan blalong chemical co. LTD 2710913286@qq.com 1513643261@qq.com China 14227 58
Cato Research Chemicals Inc. +86-020-81960175-877 4000-868-328;4000-868-328 tianwen.zhan@cato-chem.com United States 10384 58
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829 sales@mitachieve.com China 8857 58
Energy Chemical 400-0056266 marketing1@energy-chemical.com China 44927 58
Suzhou Hosyn Pharm Ltd. 17621975170; 17621975170 sales@hosynpharm.com China 1735 58
Changzhou Xianglong Pharmaceutical Technology Co., Ltd., 18915873328 18915873328 sales@xianglongpharm.com China 11049 58
4-(4-(tert-butoxycarbonyl)piperazin-1-yl)benzo[b]thiophene-2-carboxylic acid Raloxifene Impurity 11 1-Piperazinecarboxylic acid, 4-(2-carboxybenzo[b]thien-4-yl)-, 1-(1,1-dimethylethyl) ester 1677681-02-5