ChemicalBook >> CAS DataBase List >>CCI 006)
CCI 006)
- CAS No.
- 292053-42-0
- Chemical Name:
- CCI 006)
- Synonyms
- CCI 006);CCI-006 (CCI006;CCI-006, 10 mM in DMSO;Methyl 2-cyano-3-(5-(4-sulfamoylphenyl)furan-2-yl)acrylate;METHYL 3-(5-(4-(AMINOSULFONYL)PHENYL)-2-FURYL)-2-CYANOACRYLATE;CCI-006,Inhibitor,CCI006,inhibit,Mitochondrial Metabolism,CCI 006;2-Propenoic acid, 3-[5-[4-(aminosulfonyl)phenyl]-2-furanyl]-2-cyano-, methyl ester
- CBNumber:
- CB24844622
- Molecular Formula:
- C15H12N2O5S
- Molecular Weight:
- 332.33
- MDL Number:
- MFCD01847328
- MOL File:
- 292053-42-0.mol
Last updated:2025-04-30 13:36:08
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
CCI 006) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0084979 | CCI-006 98.79% | 292053-42-0 | 5mg | $350 | 2021-12-16 | Buy |
| ChemScene | CS-0084979 | CCI-006 98.79% | 292053-42-0 | 10mg | $550 | 2021-12-16 | Buy |
| ChemScene | CS-0084979 | CCI-006 98.79% | 292053-42-0 | 50mg | $1650 | 2021-12-16 | Buy |
| Ambeed | A1234954 | Methyl2-cyano-3-(5-(4-sulfamoylphenyl)furan-2-yl)acrylate 98% | 292053-42-0 | 250mg | $620 | 2021-12-16 | Buy |
| Ambeed | A1234954 | Methyl2-cyano-3-(5-(4-sulfamoylphenyl)furan-2-yl)acrylate 98% | 292053-42-0 | 1g | $1540 | 2021-12-16 | Buy |
CCI 006) Chemical Properties,Uses,Production
Uses
CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells, by inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response (UPR) in a subset of MLL-r leukemia cells[1].
References
[1] Somers K, et al. A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction. Oncogene. 2019 Jan 22. DOI:10.1038/s41388-018-0666-5
CCI 006) Preparation Products And Raw materials
Raw materials
Preparation Products
CCI 006) Suppliers
Global( 20)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32274 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38664 | 58 | |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| MQ (shanghai) Pharmaceuticals Co., Ltd. | 13761635123 | 1014988033@qq.com | China | 4966 | 55 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29771 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 60000 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24872 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9835 | 58 |
View Lastest Price from CCI 006) manufacturers
CCI 006)
CCI-006
(CCI006
2-Propenoic acid, 3-[5-[4-(aminosulfonyl)phenyl]-2-furanyl]-2-cyano-, methyl ester
Methyl 2-cyano-3-(5-(4-sulfamoylphenyl)furan-2-yl)acrylate
CCI-006,Inhibitor,CCI006,inhibit,Mitochondrial Metabolism,CCI 006
CCI-006, 10 mM in DMSO
METHYL 3-(5-(4-(AMINOSULFONYL)PHENYL)-2-FURYL)-2-CYANOACRYLATE
292053-42-0