Saxagliptin Impurity 31

Saxagliptin Impurity 16 Saxagliptin Impurity 6 3H-Cyclopropa[4,5]pyrrolo[1,2-a]pyrazin-3-one, 6-aMino-1,1a,4,6a,7,7a-hexahydro-4-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-, (1aS,4S,6aR,7aS)- Saxagliptin Impurity 32 1H-Cyclopropa[4,5]pyrrolo[1,2-a]pyrazine-3,6-dione, hexahydro-4-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-, (1aS,4S,6aR,7aS)-

(1R,3R,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide 2,2,2-trifluoroacetate Saxagliptin Impurity 8 (N-Formyl Saxagliptin) Saxagliptin Impurity 3 ((1S, 3R, 5R, 2'R)-Saxagliptin) Saxagliptin Impurity 34 Saxagliptin Impurity 22

(1R,3S,5R)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXAMIDE 2,2,2-TRIFLUOROACETIC ACID (1S,3R,5S)-2-tert-Butyl 3-ethyl 2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate Saxagliptin Impurity 5 (Epoxy saxaglliptin) Saxagliptin Impurity 29 Saxagliptin Impurity 24

Saxagliptin Impurity 4 (Deoxy Saxagliptin) Saxagliptin Impurity 33 Saxagliptin Impurity 25