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ChemicalBook >> CAS DataBase List >>3-[1-Methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylphenol

3-[1-Methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylphenol

3-[1-Methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylphenol Structure
3-[1-Methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylphenol structure
CAS No.
1198357-79-7
Chemical Name:
3-[1-Methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylphenol
Synonyms
ETP 45658;ETP-45658, 10 mM in DMSO;3-(1-Methyl-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenol;3-[1-Methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylphenol;Phenol, 3-[1-methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]-;Inhibitor,PI3K,breast,DNA-PK,Mammalian target of Rapamycin,DNA-dependent protein kinase,mTOR,inhibit,Phosphoinositide 3-kinase,ETP-45658,cancer
CBNumber:
CB24902630
Molecular Formula:
C16H17N5O2
Molecular Weight:
311.34
MDL Number:
MFCD29081201
MOL File:
1198357-79-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-22 18:57:36
Product description Number Pack Size Price
ETP45658 ≥98%(HPLC) 4702 10 $205
ETP45658 ≥98%(HPLC) 4702 50 $865
ETP45658 E936915 5mg $115
ETP45658 E936915 10mg $185
Request For Quotation

3-[1-Methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylphenol Properties

Density 1.44±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form Solid
pka 9.18±0.10(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

3-[1-Methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylphenol price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 4702 ETP45658 ≥98%(HPLC) 1198357-79-7 10 $205 2021-12-16 Buy
Tocris 4702 ETP45658 ≥98%(HPLC) 1198357-79-7 50 $865 2021-12-16 Buy
TRC E936915 ETP45658 1198357-79-7 5mg $115 2021-12-16 Buy
TRC E936915 ETP45658 1198357-79-7 10mg $185 2021-12-16 Buy
Product number Packaging Price Buy
4702 10 $205 Buy
4702 50 $865 Buy
E936915 5mg $115 Buy
E936915 10mg $185 Buy

3-[1-Methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylphenol Chemical Properties,Uses,Production

Uses

ETP 45658 is a potent and selective inhibitor of phosphoinositol 3-kinase and demonstrates mechanism of action in tumor cells, inhibitors of mTOR kinase as antiviral agents.

in vivo

ETP-45658 (22.7 mg/kg) decreases the level of phosphorylated Akt on serine 473 in the mammary ducts of transgenic mice[1].

IC 50

PI3Kα: 22.0 nM (IC50); PI3Kδ: 39.8 nM (IC50); PI3Kβ: 129.0 nM (IC50); PI3Kγ: 717.3 nM (IC50); DNA-PK: 70.6 nM (IC50); mTOR: 152.0 nM (IC50)

storage

Store at +4°C

3-[1-Methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylphenol Preparation Products And Raw materials

Raw materials

Preparation Products

3-[1-Methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylphenol Suppliers

Global( 29)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32467 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 89689 60
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9697 55
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
BOC Sciences -- info@bocsci.com USA 0 65
Hefei Mokai Pharmaceutical Technology Co., Ltd 18130062233 690231469@qq.com China 8100 58
Hubei Kele Fine Chemical Co., Ltd 027-59101668 19945030958 2223443625@qq.com China 7991 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59936 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24960 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Shanghai YuanYe Biotechnology Co., Ltd. 60
Tianjin Kailiqi Biotechnology Co., Ltd. 55
Shanghai Hongye Biotechnology Co. Ltd 58
BOC Sciences 65
Hefei Mokai Pharmaceutical Technology Co., Ltd 58
Hubei Kele Fine Chemical Co., Ltd 58
Bide Pharmatech Ltd. 58
TargetMol Chemicals Inc. 58

View Lastest Price from 3-[1-Methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylphenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ETP-45658 pictures 2026-04-22 ETP-45658
1198357-79-7
 US $48.00-185.00 / mg 99.14% 10g TargetMol Chemicals Inc.
  • ETP-45658 pictures
  • ETP-45658
    1198357-79-7
  • US $48.00-185.00 / mg
  • 99.14%
  • TargetMol Chemicals Inc.

3-[1-Methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylphenol Spectrum

3-[1-Methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylphenol(1198357-79-7)1HNMR
3-[1-Methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylphenol ETP 45658 3-(1-Methyl-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenol Inhibitor,PI3K,breast,DNA-PK,Mammalian target of Rapamycin,DNA-dependent protein kinase,mTOR,inhibit,Phosphoinositide 3-kinase,ETP-45658,cancer Phenol, 3-[1-methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]- ETP-45658, 10 mM in DMSO 1198357-79-7