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4′′,5′′-dehydroisopsoralidin

CAS No.
65639-51-2
Chemical Name:
4′′,5′′-dehydroisopsoralidin
Synonyms
4′′,5′′-dehydroisopsoralidin;10-Hydroxy-3,3-dimethylbenzofuro[3,2-c]pyrano[3,2-g]chromen-7(3H)-one;3H,7H-Benzofuro[3,2-c]pyrano[3,2-g][1]benzopyran-7-one, 10-hydroxy-3,3-dimethyl- (9CI)
CBNumber:
CB24923668
Molecular Formula:
C20H14O5
Molecular Weight:
334.32
MDL Number:
MOL File:
65639-51-2.mol
Last updated:2025-04-18 09:51:59

4′′,5′′-dehydroisopsoralidin Properties

Boiling point 432.4±45.0 °C(Predicted)
Density 1.401±0.06 g/cm3(Predicted)
pka 8.80±0.40(Predicted)

4′′,5′′-dehydroisopsoralidin Chemical Properties,Uses,Production

Uses

4'',5''-Dehydroisopsoralidin is a β-glucuronidase inhibitor (IC50: 6.3 μM). 4'',5''-Dehydroisopsoralidin has anti-inflammatory and anti-oxidative effects. 4'',5''-Dehydroisopsoralidin can be used in the research of inflammation and cancners[1][2].

References

[1] De-Wu Zhang, et al. Solalyratins A and B, new anti-inflammatory metabolites from Solanum lyratum. J Nat Med. 2012 Apr;66(2):362-6. DOI:10.1007/s11418-011-0581-3
[2] Christian Limper, et al. Compounds isolated from Psoralea corylifolia seeds inhibit protein kinase activity and induce apoptotic cell death in mammalian cells. J Pharm Pharmacol. 2013 Sep;65(9):1393-408. DOI:10.1111/jphp.12107
[3] Tong-Hong Wang, et al. The flavonoid corylin exhibits lifespan extension properties in mouse. Nat Commun. 2022 Mar 9;13(1):1238. DOI:10.1038/s41467-022-28908-2

4′′,5′′-dehydroisopsoralidin Preparation Products And Raw materials

Raw materials

Preparation Products

4′′,5′′-dehydroisopsoralidin Suppliers

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Apeloa Pharmaceutical Co., Ltd.
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Shanghai Hewu Biotechnology Co., LTD 021-57886085 17317861055 shhebio@126.com CHINA 7974 58
4′′,5′′-dehydroisopsoralidin 3H,7H-Benzofuro[3,2-c]pyrano[3,2-g][1]benzopyran-7-one, 10-hydroxy-3,3-dimethyl- (9CI) 10-Hydroxy-3,3-dimethylbenzofuro[3,2-c]pyrano[3,2-g]chromen-7(3H)-one 65639-51-2