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4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN&

4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& structure

CAS No.: 87184-99-4

Chemical Name:: 4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN&

Synonyms: DKSI083;DKFELEX0278;TBDMS-Bu-OH;4-tert-Butyldimethylsilyloxybutanol;4-(t-BUTYLDIMETHYLSILOXY)BUTAN-1-OL;4-(tert-butyldimethylsiloxy)-1-butanol;4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN&;4-[t-Butyl(Dimethyl)Silyl] Oxybutan-1-Ol;4-tert-ButyldiMethylsiloxy-1-butanol, 97%;1-tert-ButyldiMethylsilyl-4-hydroxybutane

CBNumber:: CB2500089

Molecular Formula:: C10H24O2Si

Molecular Weight:: 204.38

MDL Number:: MFCD04974070

MOL File:: 87184-99-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:48

Product description	Number	Pack Size	Price
4-(tert-Butyldimethylsilyl)oxy-1-butanol 97%	568589	5g	$50.3
4-(Dimethyl-tert-Butylsilyloxy)butan-1-ol	D468260	10g	$970
4-(Dimethyl-tert-butylsilyloxy)butan-1-ol	FD22408	50g	$480
4-(Dimethyl-tert-butylsilyloxy)butan-1-ol	FD22408	10g	$160
4-(Dimethyl-tert-butylsilyloxy)butan-1-ol	FD22408	25g	$300
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4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& Properties

Boiling point	63-66 °C/0.3 mmHg (lit.)
Density	0.888 g/mL at 25 °C (lit.)
refractive index	n20/D 1.4390(lit.)
Flash point	222 °C
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	soluble in Dichloromethane, Ethyl Acetate, Methanol
pka	15.07±0.10(Predicted)
form	Oil
color	Colourless
Specific Gravity	0.888
Water Solubility	Slightly Soluble in water.(2.0 g/L) (25°C). Soluble in Dichloromethane, Ethyl Acetate, Methanol
Hydrolytic Sensitivity	7: reacts slowly with moisture/water
InChI	InChI=1S/C10H24O2Si/c1-10(2,3)13(4,5)12-9-7-6-8-11/h11H,6-9H2,1-5H3
InChIKey	IJEMXJANZPVITP-UHFFFAOYSA-N
SMILES	C(O)CCCO[Si](C(C)(C)C)(C)C
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P305+P351+P338

PPE

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

WGK Germany

Storage Class

10 - Combustible liquids

NFPA 704

	1
0		0

4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& price More Price(18)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	568589	4-(tert-Butyldimethylsilyl)oxy-1-butanol 97%	87184-99-4	5g	$50.3	2022-05-15	Buy
TRC	D468260	4-(Dimethyl-tert-Butylsilyloxy)butan-1-ol	87184-99-4	10g	$970	2021-12-16	Buy
Biosynth Carbosynth	FD22408	4-(Dimethyl-tert-butylsilyloxy)butan-1-ol	87184-99-4	50g	$480	2021-12-16	Buy
Biosynth Carbosynth	FD22408	4-(Dimethyl-tert-butylsilyloxy)butan-1-ol	87184-99-4	10g	$160	2021-12-16	Buy
Biosynth Carbosynth	FD22408	4-(Dimethyl-tert-butylsilyloxy)butan-1-ol	87184-99-4	25g	$300	2021-12-16	Buy

Product number	Packaging	Price	Buy
568589	5g	$50.3	Buy
D468260	10g	$970	Buy
FD22408	50g	$480	Buy
FD22408	10g	$160	Buy
FD22408	25g	$300	Buy

4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& Chemical Properties,Uses,Production

Chemical Properties

Colourless Oil

Uses

4-(Dimethyl-tert-Butylsilyloxy)butan-1-ol (cas# 87184-99-4) is a compound useful in organic synthesis.

Synthesis

110-63-4

18162-48-6

4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN&

87184-99-4

To a stirred solution of 1,4-butanediol (3 mL, 33.3 mmol) in anhydrous dichloromethane (30 mL) was added imidazole (2.73 g, 66.6 mmol) at 0 °C and the mixture was stirred for 30 min. Subsequently, tert-butyldimethylchlorosilane (TBSCl, 5 g, 33.3 mmol) dissolved in dichloromethane (20 mL) was added and the mixture was stirred at room temperature for 1 hour (the progress of the reaction was monitored by TLC). Upon completion of the reaction, the reaction mixture was quenched with saturated sodium bicarbonate solution. Next, it was washed with ammonium chloride solution and extracted with dichloromethane (2 x 30 mL). The organic extracts were combined, washed with brine, dried over anhydrous sodium sulfate, and concentrated under vacuum. Finally, the residue was purified by column chromatography (silica gel, ethyl acetate-hexane, 2:8) to afford 4-((tert-butyldimethylsilyl)oxy)butan-1-ol (TBS ether) as a colorless slurry; yield: 6.4 g (95%).

References

[1] Journal of Organic Chemistry, 2005, vol. 70, # 16, p. 6321 - 6329
[2] Organic and Biomolecular Chemistry, 2016, vol. 14, # 40, p. 9554 - 9559
[3] European Journal of Organic Chemistry, 2017, vol. 2017, # 23, p. 3362 - 3372
[4] Tetrahedron, 2003, vol. 59, # 6, p. 833 - 839
[5] Journal of Organic Chemistry, 2004, vol. 69, # 19, p. 6419 - 6426

4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& Preparation Products And Raw materials

Raw materials

1,4-Butanediol 4,9-Dioxa-3,10-disiladodecane, 2,2,3,3,10,10,11,11-octamethyl- tert-Butyldimethylsilyl chloride Dichloromethane Imidazole

Preparation Products

4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& Suppliers

Global( 115)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	16513	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13843	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29819	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
CD Chemical Group Limited	+8615986615575	info@codchem.com	China	17259	58
Alfa Chemistry	+1-5166625404;	Info@alfa-chemistry.com	United States	20405	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	24597	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58

Supplier	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Shanghai Daken Advanced Materials Co.,Ltd	58
career henan chemical co	58
Accela ChemBio Inc.	58
ANHUI WITOP BIOTECH CO., LTD	58
CD Chemical Group Limited	58
Alfa Chemistry	58
HANGZHOU LEAP CHEM CO., LTD.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Aladdin Scientific	58

View Lastest Price from 4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-04-17	4-tert-Butyldimethylsiloxy-1-butanol 87184-99-4	US $1.10-9.90 / kg	100kg	99%min	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
	2019-09-02	4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& 87184-99-4	US $1.00 / KG	1KG	≥98%	200KG	Career Henan Chemical Co

4-tert-Butyldimethylsiloxy-1-butanol
87184-99-4
US $1.10-9.90 / kg
99%min
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN&
87184-99-4
US $1.00 / KG
≥98%
Career Henan Chemical Co

4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& Spectrum

4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN&(87184-99-4)¹HNMR

4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& 4-(tert-Butyldimethylsilyl)oxy-1-butanol 97% 4-[Tert-Butyl(Dimethyl)Silyl]Oxybutan-1-Ol 1-tert-ButyldiMethylsilyl-4-hydroxybutane 4-[[(1,1-DiMethylethyl)diMethylsilyl]oxy]-1-butanol 4-tert-ButyldiMethylsiloxy-1-butanol, 97% 4-tert-Butyldimethylsilyloxybutanol 4-(tert-Butyldimethylsiloxy)butanol300374-99-6 4-[t-Butyl(Dimethyl)Silyl] Oxybutan-1-Ol 4-(t-BUTYLDIMETHYLSILOXY)BUTAN-1-OL 1-Butanol, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]- 4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& DKFELEX0278 DKSI083 4-(tert-Butyldimethylsilyl)oxy-1-butanol TBDMS-Bu-OH 4-(tert-butyldimethylsiloxy)-1-butanol 87184-99-4 CH33CSiCH32OCH24OH Aliphatics Alcohols C9 to C30 Oxygen Compounds