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4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN&

CAS No.
87184-99-4
Chemical Name:
4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN&
Synonyms
DKSI083;DKFELEX0278;TBDMS-Bu-OH;4-tert-Butyldimethylsilyloxybutanol;4-(t-BUTYLDIMETHYLSILOXY)BUTAN-1-OL;4-(tert-butyldimethylsiloxy)-1-butanol;4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN&;4-[t-Butyl(Dimethyl)Silyl] Oxybutan-1-Ol;4-tert-ButyldiMethylsiloxy-1-butanol, 97%;1-tert-ButyldiMethylsilyl-4-hydroxybutane
CBNumber:
CB2500089
Molecular Formula:
C10H24O2Si
Molecular Weight:
204.38
MDL Number:
MFCD04974070
MOL File:
87184-99-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-05 19:35:02
Product description Number Pack Size Price
4-(tert-Butyldimethylsilyl)oxy-1-butanol 97% 568589 5g $50.3
4-(Dimethyl-tert-Butylsilyloxy)butan-1-ol TRC-D468260-1G 1g $167
4-(Dimethyl-tert-Butylsilyloxy)butan-1-ol TRC-D468260-10G 10g $1312
4-(tert-Butyldimethylsilyl)oxy-1-butanol ≥98%(GC) 31352 5G $41.76
4-(tert-Butyldimethylsilyl)oxy-1-butanol ≥98%(GC) 31352 25G $161.14
More product size

4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& Properties

Boiling point 63-66 °C/0.3 mmHg (lit.)
Density 0.888 g/mL at 25 °C (lit.)
refractive index n20/D 1.4390(lit.)
Flash point 222 °C
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility soluble in Dichloromethane, Ethyl Acetate, Methanol
form Oil
pka 15.07±0.10(Predicted)
Specific Gravity 0.888
color Colourless
Water Solubility Slightly Soluble in water.(2.0 g/L) (25°C). Soluble in Dichloromethane, Ethyl Acetate, Methanol
Hydrolytic Sensitivity 7: reacts slowly with moisture/water
InChI InChI=1S/C10H24O2Si/c1-10(2,3)13(4,5)12-9-7-6-8-11/h11H,6-9H2,1-5H3
InChIKey IJEMXJANZPVITP-UHFFFAOYSA-N
SMILES C(O)CCCO[Si](C(C)(C)C)(C)C
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
PPE Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
WGK Germany  3
Storage Class 10 - Combustible liquids
NFPA 704
1
0 0

4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 568589 4-(tert-Butyldimethylsilyl)oxy-1-butanol 97% 87184-99-4 5g $50.3 2022-05-15 Buy
TRC TRC-D468260-1G 4-(Dimethyl-tert-Butylsilyloxy)butan-1-ol 87184-99-4 1g $167 2026-06-03 Buy
TRC TRC-D468260-10G 4-(Dimethyl-tert-Butylsilyloxy)butan-1-ol 87184-99-4 10g $1312 2026-06-03 Buy
Chem-Impex 31352 4-(tert-Butyldimethylsilyl)oxy-1-butanol ≥98%(GC) 87184-99-4 5G $41.76 2026-05-19 Buy
Chem-Impex 31352 4-(tert-Butyldimethylsilyl)oxy-1-butanol ≥98%(GC) 87184-99-4 25G $161.14 2026-05-19 Buy
Product number Packaging Price Buy
568589 5g $50.3 Buy
TRC-D468260-1G 1g $167 Buy
TRC-D468260-10G 10g $1312 Buy
31352 5G $41.76 Buy
31352 25G $161.14 Buy

4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& Chemical Properties,Uses,Production

Chemical Properties

Colourless Oil

Uses

4-(Dimethyl-tert-Butylsilyloxy)butan-1-ol (cas# 87184-99-4) is a compound useful in organic synthesis.

Synthesis

1,4-Butanediol

110-63-4

tert-Butyldimethylsilyl chloride

18162-48-6

4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN&

87184-99-4

To a stirred solution of 1,4-butanediol (3 mL, 33.3 mmol) in anhydrous dichloromethane (30 mL) was added imidazole (2.73 g, 66.6 mmol) at 0 °C and the mixture was stirred for 30 min. Subsequently, tert-butyldimethylchlorosilane (TBSCl, 5 g, 33.3 mmol) dissolved in dichloromethane (20 mL) was added and the mixture was stirred at room temperature for 1 hour (the progress of the reaction was monitored by TLC). Upon completion of the reaction, the reaction mixture was quenched with saturated sodium bicarbonate solution. Next, it was washed with ammonium chloride solution and extracted with dichloromethane (2 x 30 mL). The organic extracts were combined, washed with brine, dried over anhydrous sodium sulfate, and concentrated under vacuum. Finally, the residue was purified by column chromatography (silica gel, ethyl acetate-hexane, 2:8) to afford 4-((tert-butyldimethylsilyl)oxy)butan-1-ol (TBS ether) as a colorless slurry; yield: 6.4 g (95%).

References

[1] Journal of Organic Chemistry, 2005, vol. 70, # 16, p. 6321 - 6329
[2] Organic and Biomolecular Chemistry, 2016, vol. 14, # 40, p. 9554 - 9559
[3] European Journal of Organic Chemistry, 2017, vol. 2017, # 23, p. 3362 - 3372
[4] Tetrahedron, 2003, vol. 59, # 6, p. 833 - 839
[5] Journal of Organic Chemistry, 2004, vol. 69, # 19, p. 6419 - 6426

4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& Preparation Products And Raw materials

Global( 118)Suppliers
Supplier Tel Email Country ProdList Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
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Junwee Chemical co., Ltd.
+86-571-85808636 +86-13958122542 sales@junweechem.com China 823 58

View Lastest Price from 4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& pictures 2026-08-05 4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN&
87184-99-4
1KG 98% 1000kgs Shaanxi Dideu New Materials Co. Ltd
4-tert-Butyldimethylsiloxy-1-butanol pictures 2026-07-02 4-tert-Butyldimethylsiloxy-1-butanol
87184-99-4
$1.10-9.90 100kg 99%min 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& pictures 2019-09-02 4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN&
87184-99-4
$1.00 1KG ≥98% 200KG Career Henan Chemical Co

4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& Spectrum

4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& 4-(tert-Butyldimethylsilyl)oxy-1-butanol 97% 4-[Tert-Butyl(Dimethyl)Silyl]Oxybutan-1-Ol 1-tert-ButyldiMethylsilyl-4-hydroxybutane 4-[[(1,1-DiMethylethyl)diMethylsilyl]oxy]-1-butanol 4-tert-ButyldiMethylsiloxy-1-butanol, 97% 4-tert-Butyldimethylsilyloxybutanol 4-(tert-Butyldimethylsiloxy)butanol300374-99-6 4-[t-Butyl(Dimethyl)Silyl] Oxybutan-1-Ol 4-(t-BUTYLDIMETHYLSILOXY)BUTAN-1-OL 1-Butanol, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]- 4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& DKFELEX0278 DKSI083 4-(tert-Butyldimethylsilyl)oxy-1-butanol TBDMS-Bu-OH 4-(tert-butyldimethylsiloxy)-1-butanol 87184-99-4 CH33CSiCH32OCH24OH Aliphatics Alcohols C9 to C30 Oxygen Compounds