2 6-DICHLOROPYRIDINE-3-CARBOXALDEHYDE
- CAS No.
- 55304-73-9
- Chemical Name:
- 2 6-DICHLOROPYRIDINE-3-CARBOXALDEHYDE
- Synonyms
- CML-018;2,6-Dichloronicotinaldehyde;2,6-Dichloropyridine-3-ca...;2,6- twochlorine sMokealdehyde;2,6-Dichloropyridine-3-carbaldehyde;2,6-Dichloro-3-pyridinecarbaldehyde;2,6-Dichloropyridin-3-carboxaldehyde;2,6-Dichloro-3-pyridinecarboxaldehyde;3-Pyridinecarboxaldehyde,2,6-dichloro-(;2,6-Dichloro-3-pyridinecarboxaldehyde>
- CBNumber:
- CB2500337
- Molecular Formula:
- C6H3Cl2NO
- Molecular Weight:
- 176
- MDL Number:
- MFCD07369746
- MOL File:
- 55304-73-9.mol
- MSDS File:
- SDS
| Melting point | 74-75 °C (lit.) |
|---|---|
| Boiling point | 95°C/3mmHg(lit.) |
| Density | 1.488±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | powder to crystal |
| pka | -4.52±0.10(Predicted) |
| color | White to Orange to Green |
| InChI | InChI=1S/C6H3Cl2NO/c7-5-2-1-4(3-10)6(8)9-5/h1-3H |
| InChIKey | HWTMRGXKSANEDO-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NC(Cl)=CC=C1C=O |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H317-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P280-P301+P310-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38-43 | |||||||||
| Safety Statements | 26-36/37 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| PackingGroup | Ⅲ | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
2 6-DICHLOROPYRIDINE-3-CARBOXALDEHYDE price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 651958 | 2,6-Dichloropyridine-3-carboxaldehyde 97% | 55304-73-9 | 5g | $596 | 2023-06-20 | Buy |
| Sigma-Aldrich | 651958 | 2,6-Dichloropyridine-3-carboxaldehyde 97% | 55304-73-9 | 1g | $109 | 2022-05-15 | Buy |
| TCI Chemical | D4651 | 2,6-Dichloro-3-pyridinecarboxaldehyde >98.0%(GC) | 55304-73-9 | 1g | $51 | 2025-07-31 | Buy |
| TCI Chemical | D4651 | 2,6-Dichloro-3-pyridinecarboxaldehyde >98.0%(GC) | 55304-73-9 | 5g | $167 | 2025-07-31 | Buy |
| TRC | D476043 | 2,6-dichloropyridine-3-carbaldehyde | 55304-73-9 | 5g | $90 | 2021-12-16 | Buy |
2 6-DICHLOROPYRIDINE-3-CARBOXALDEHYDE Chemical Properties,Uses,Production
Synthesis
55304-90-0
55304-73-9
The general procedure for the synthesis of 2,6-dichloro-3-pyridinecarboxaldehyde from 2,6-dichloro-3-hydroxymethylpyridine was as follows: to a solution of (2,6-dichloropyridin-3-yl)methanol (1.0 g, 5.62 mmol) in dichloromethane (10 ml) was added Dess-Martin reagent (4.8 g, 11.24 mmol) at 26 °C. After addition, the reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the reaction was quenched by addition of 5% Na2S2O3 aqueous solution and stirring was continued for 30 min. The reaction mixture was extracted with dichloromethane (2 x 30 ml). The organic layers were combined and washed sequentially with saturated Na2S2O3 solution (50 ml), brine (30 ml), dried over anhydrous Na2SO4, and concentrated under reduced pressure to afford the crude 2,6-dichloro-3-pyridinecarboxaldehyde (800 mg, 80% yield), which was used directly in the next step of the reaction. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 10.38 (s, 1H), 8.19 (d, J = 8.0Hz, 1H), 7.44 (d, J = 8.0Hz, 1H).
References
[1] Patent: WO2014/100695, 2014, A1. Location in patent: Paragraph 00409
[2] Journal of Organic Chemistry, 1982, vol. 47, # 14, p. 2800 - 2802
[3] Patent: WO2006/44454, 2006, A1. Location in patent: Page/Page column 62
[4] Patent: US3974166, 1976, A
2 6-DICHLOROPYRIDINE-3-CARBOXALDEHYDE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 9029 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29734 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29852 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
View Lastest Price from 2 6-DICHLOROPYRIDINE-3-CARBOXALDEHYDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-08-15 | 2,6-Dichloro-3-formylpyridine
55304-73-9
|
US $1.10-9.90 / kg | 1kg | 99%min | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2021-10-27 | 2 6-DICHLOROPYRIDINE-3-CARBOXALDEHYDE
55304-73-9
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2019-07-06 | 2 6-DICHLOROPYRIDINE-3-CARBOXALDEHYDE
55304-73-9
|
US $1.00 / kg | 1kg | 99% | Customized | Career Henan Chemical Co |
-
- 2,6-Dichloro-3-formylpyridine
55304-73-9
- US $1.10-9.90 / kg
- 99%min
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 2 6-DICHLOROPYRIDINE-3-CARBOXALDEHYDE
55304-73-9
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 2 6-DICHLOROPYRIDINE-3-CARBOXALDEHYDE
55304-73-9
- US $1.00 / kg
- 99%
- Career Henan Chemical Co
55304-73-9(2 6-DICHLOROPYRIDINE-3-CARBOXALDEHYDE)Related Search:
1of4
