LMPTP INHIBITOR 1 dihydrochloride
- CAS No.
- 2310135-46-5
- Chemical Name:
- LMPTP INHIBITOR 1 dihydrochloride
- Synonyms
- YUN35454;LMPTP INHIBITOR 1 dihydrochloride;LMW-PTP Inhibitor I (hydrochloride);LMPTP INHIBITOR 1 dihydrochloride, 10 mM in DMSO;N,N-Diethyl-4-(4-((3-(piperidin-1-yl)propyl)amino)quinolin-2-yl)benzamide dihydrochloride;inhibit,LMPTP inhibitor-1,LMPTP inhibitor 1,LMPTP INHIBITOR 1 dihydrochloride,Phosphatase,LMPTP inhibitor1,Inhibitor
- CBNumber:
- CB25419773
- Molecular Formula:
- C28H37ClN4O
- Molecular Weight:
- 481.08
- MDL Number:
- MFCD31807303
- MOL File:
- 2310135-46-5.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| NFPA 704 |
|
LMPTP INHIBITOR 1 dihydrochloride price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 22277 | LMW-PTP Inhibitor I (hydrochloride) ≥98% | 2310135-46-5 | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 22277 | LMW-PTP Inhibitor I (hydrochloride) ≥98% | 2310135-46-5 | 5mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 22277 | LMW-PTP Inhibitor I (hydrochloride) ≥98% | 2310135-46-5 | 10mg | $283 | 2024-03-01 | Buy |
| Cayman Chemical | 22277 | LMW-PTP Inhibitor I (hydrochloride) ≥98% | 2310135-46-5 | 25mg | $618 | 2024-03-01 | Buy |
| ChemScene | CS-0045260 | LMPTPINHIBITOR1dihydrochloride 99.63% | 2310135-46-5 | 5mg | $350 | 2021-12-16 | Buy |
LMPTP INHIBITOR 1 dihydrochloride Chemical Properties,Uses,Production
Uses
LMPTP INHIBITOR 1 (dihydrochloride) is a selective inhibitor of low molecular weight protein tyrosine phosphatase (LMPTP), with an IC50 of 0.8 μM LMPTP-A.
in vivo
LMPTP inhibitor 1 is orally bioavailable, and results in appr 680 nM mean serum concentration after treatment of 0.03% w/w, while treatment with 0.05% w/w results in >3 μM; also reverses diabetes in obese mice. LMPTP inhibitor 1 (0.05% w/w) inhibits LMPTP activity, significantly improves glucose tolerance and decreases fasting insulin levels of diabetic DIO mice, without affecting body weight[1].
References
[1] Stanford SM1, et al. Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase. Nat Chem Biol. 2017 Jun;13(6):624-632. DOI:10.1038/nchembio.2344
LMPTP INHIBITOR 1 dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
LMPTP INHIBITOR 1 dihydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32268 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38663 | 58 | |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
| Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2959 | 58 |
| Shanghai Chaolan Chemical Technology Center | 021-QQ：65489617 15618227136 | Sales@ATKchemical.com | China | 9342 | 58 |
| Wuxi Donghe Pharmaceutical Technology Co., Ltd. | 63313187 15358055255 | 63313187@qq.com | China | 1988 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
View Lastest Price from LMPTP INHIBITOR 1 dihydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-05-01 | LMPTP INHIBITOR 1 dihydrochloride
2310135-46-5
|
US $70.00-278.00 / mg | 99.49% | 10g | TargetMol Chemicals Inc. |
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- LMPTP INHIBITOR 1 dihydrochloride
2310135-46-5
- US $70.00-278.00 / mg
- 99.49%
- TargetMol Chemicals Inc.