CCN3 antibody
- CAS No.
- Chemical Name:
- CCN3 antibody
- Synonyms
- CCN3 antibody;Rabbit Polyclonal CCN3 Antibody
- CBNumber:
- CB25612833
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
CCN3 antibody Chemical Properties, Uses, Production
Source
Rabbit
Reactivity
Human;Mouse;Rat;Monkey
Background
CCN3, also named NOV, belongs to the CCN family of proteins. It is a cystine-rich secretory protein that associates with components of the extracellular matrix. Like other CCN family members, CCN3 is capable of mediating diverse biological functions through its four distinct domains, which enable binding to numerous protein partners.CCN3 modulates bone turnover through various mechanisms and is implicated in the progression of primary bone cancers such as osteosarcoma and chondrosarcoma. Research has shown that CCN3 is also involved in the bone metastasis of melanoma, breast cancer, and prostate cancers. Recently, CCN3 was reported to play an important role in stem cell renewal. CCN3 is normally expressed in both embryonic and adult tissues. The activity of CCN3 is influenced by post translational modifications and proteolytic cleavage.
References
[1] Perbal, B. (2001) Mol Pathol 54, 57-79.
[2] Brigstock, D.R. et al. (2003) Mol Pathol 56, 127-8.
[3] Leask, A. and Abraham, D.J. (2006) J Cell Sci 119, 4803-10.
[4] Yeger, H. and Perbal, B. (2007) J Cell Commun Signal 1, 159-64.
[5] McCallum, L. and Irvine, A.E. (2009) Blood Rev 23, 79-85.
[6] Perbal, B. et al. (2008) Clin Cancer Res 14, 701-9.
[7] Tzeng, H.E. et al. (2011) J Cell Physiol 226, 3181-9.
[8] Yang, W. et al. (2011) Hum Reprod 26, 2850-60.
[9] Vallacchi, V. et al. (2008) Cancer Res 68, 715-23.
[10] Ouellet, V. et al. (2011) Am J Pathol 178, 2377-88.
CCN3 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
CCN3 antibody Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Ipodix Biotechnology Co.,Ltd. | 18007124176 19384116026 | 2706668885@qq.com | China | 4987 | 58 |
| Supplier | Advantage |
|---|---|
| Hubei Ipodix Biotechnology Co.,Ltd. | 58 |
