MFF antibody

CAS No.
Chemical Name:
MFF antibody
Synonyms
MFF antibody
CBNumber:
CB25654091
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file

MFF antibody price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biorbyt Ltd orb254069 MFF Antibody 100μl $360 2026-05-06 Buy
Biorbyt Ltd orb101576 MFF antibody Affinity purified by Protein A 100μg $421.6 2021-12-16 Buy
Biorbyt Ltd orb101576 MFF antibody Affinity purified by Protein A 200μg $673.2 2021-12-16 Buy
Product number Packaging Price Buy
orb254069 100μl $360 Buy
orb101576 100μg $421.6 Buy
orb101576 200μg $673.2 Buy

MFF antibody Chemical Properties,Uses,Production

Source

Rabbit

Reactivity

Human;Mouse

Background

Mitochondrial fission factor is a tail-anchored protein that resides within the outer mitochondrial membrane and is part of the mitochondrial fission complex. MFF participates in mitochondrial fission by serving as one of multiple receptors for the GTPase dynamin-related protein 1. Research studies have also shown that MFF is a peroxisomal membrane protein and participates in peroxisome fission by serving as a receptor for another GTPase, dynamin-like protein 1.Research studies have demonstrated that the ability of MFF to drive acute mitochondrial fission in response to mitochondrial stress is controlled by AMPK-dependent phosphorylation. AMPK directly phosphorylates MFF at two sites to allow for enhanced recruitment of Drp1 to the mitochondra. Multiple isoforms of MFF are expressed as a result of alternative splicing. One of the major phosphoacceptor sites of MFF lies within an AMPK phsophorylation motif that spans the boundary of differentially spliced exons of MFF isoforms, suggesting that MFF splice isoforms are phosphorylated by AMPK to varying degrees.

References

[1] Liu, R. and Chan, D.C. (2015) Mol Biol Cell 26, 4466-77.
[2] Shen, Q. et al. (2014) Mol Biol Cell 25, 145-59.
[3] Losón, O.C. et al. (2013) Mol Biol Cell 24, 659-67.
[4] Otera, H. et al. (2010) J Cell Biol 191, 1141-58.
[5] Itoyama, A. et al. (2013) Biol Open 2, 998-1006.
[6] Gandre-Babbe, S. and van der Bliek, A.M. (2008) Mol Biol Cell 19, 2402-12.
[7] Toyama, E.Q. et al. (2016) Science 351, 275-81.
[8] Ducommun, S. et al. (2015) Cell Signal 27, 978-88.

MFF antibody Preparation Products And Raw materials

Raw materials

Preparation Products

MFF antibody Suppliers

Global( 51)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Ipodix Biotechnology Co.,Ltd. 18007124176 19384116026 2706668885@qq.com China 4987 58
Hubei Serenity BioSolutions Co., Ltd. 027-19371278702 18008634902 19384116026@163.com China 3008 58
MFF antibody