PRDX6 antibody

CAS No.
Chemical Name:
PRDX6 antibody
Synonyms
PRDX6 antibody;Rabbit Polyclonal PRDX6 Antibody
CBNumber:
CB25675913
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Product description Number Pack Size Price
PRDX6 Antibody orb622229 50μl $400
PRDX6 Antibody orb622229 100μl $540
PRDX6 Antibody orb192474 50μl $350
PRDX6 Antibody orb192474 100μl $480
PRDX6 antibody Antigen affinity chromatography orb178388 100μg $499.8

PRDX6 antibody price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biorbyt Ltd orb622229 PRDX6 Antibody 50μl $400 2026-05-06 Buy
Biorbyt Ltd orb622229 PRDX6 Antibody 100μl $540 2026-05-06 Buy
Biorbyt Ltd orb192474 PRDX6 Antibody 50μl $350 2026-05-06 Buy
Biorbyt Ltd orb192474 PRDX6 Antibody 100μl $480 2026-05-06 Buy
Biorbyt Ltd orb178388 PRDX6 antibody Antigen affinity chromatography 100μg $499.8 2021-12-16 Buy
Product number Packaging Price Buy
orb622229 50μl $400 Buy
orb622229 100μl $540 Buy
orb192474 50μl $350 Buy
orb192474 100μl $480 Buy
orb178388 100μg $499.8 Buy

PRDX6 antibody Chemical Properties,Uses,Production

Source

Rabbit

Applications

PRDX6 antibody has been tested by ELISA, Western blot analysis, ICC/IF and Flow cytometry to assure specificity and reactivity.

Reactivity

Human;Mouse;Rat

Immunogen

Anti-human PRDX6 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PRDX6 amino acids 1-224 purified from E. coli.

Background

Peroxiredoxin 6 (PRDX6) belongs to the thiol-specific antioxidant protein family. PRDX6 is a bifunctional enzyme with 2 distinct active sites. PRDX6 is involved in redox regulation of the cell and can reduce Hydrogen peroxide and short chain organic, fatty acid, and phospholipid hydroperoxides. PRDX6 may have a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. Furthermore, PRDX6 eases the oxidative stress and TGF-beta-induced abnormalities of human trabecular meshwork cells. In addition, PRDX6 is necessary for blood vessel integrity in injured skin.
At acidic pH, PRDX6 binds to reduced phospholipids, however at cytosolic pH PRDX6 binds only to phospholipids that are oxidized which is compatible with the role for PRDX6 in the repair of peroxidized cell membranes. Hydrogen peroxide-mediated hyperoxidation of PRDX6 induces cell cycle arrest at the G2/M transition via up-regulation of iPLA2 activity. Overexpression of PRDX6 is linked to oligodendroglioma.

References

[1] Kang, S.W. et al. (1998) J Biol Chem 273, 6303-11.
[2] Chen, J.W. et al. (2000) J Biol Chem 275, 28421-7.
[3] Manevich, Y. and Fisher, A.B. (2005) Free Radic Biol Med 38, 1422-32.
[4] Schremmer, B. et al. (2007) Subcell Biochem 44, 317-44.
[5] Lee, S.B. et al. (2009) Mol Cells 28, 583-8.
[6] Ho, J.N. et al. (2010) Mol Cancer Ther 9, 825-32.
[7] Yun, H.M. et al. (2014) Free Radic Biol Med 69, 367-76.
[8] Pak, J.H. et al. (2011) Cancer Invest 29, 21-8.
[9] Kalinina, E.V. et al. (2012) Bull Exp Biol Med 153, 878-81.
[10] Chatterjee, S. et al. (2011) J Biol Chem 286, 11696-706.

PRDX6 antibody Preparation Products And Raw materials

Raw materials

Preparation Products

PRDX6 antibody Suppliers

Global( 52)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Ipodix Biotechnology Co.,Ltd. 18007124176 19384116026 2706668885@qq.com China 4987 58
CUSABIO TECHNOLOGY LLC 027-87196173 cusabio@163.com China 6066 58
Hubei Serenity BioSolutions Co., Ltd. 027-19371278702 18008634902 19384116026@163.com China 3008 58
Enzo Biochem Inc Enzo Biochem Inc. 13797054060 Enzoname@qq.com China 6174 58
Biosynth Ltd 18886812933 sales@biosynth.com China 6218 58
Cell Signaling Technology Inc 21-80243558 86218024 info@cellsignal.cn China 6725 58
Abmart Inc 4006-123-828 13162017139 market@ab-mart.com China 6917 58
Signalway Antibody LLC 025-58868422 info@sabbiotech.com China 6243 58
Wuhan Fine Biotech Co Ltd 13047170542 marketing@fn-test.com China 6600 58
Biosynth Biological Technology (Suzhou) Co Ltd 51288865780 sales@biosynth.com China 6051 58
PRDX6 antibody Rabbit Polyclonal PRDX6 Antibody