HU-580
- CAS No.
- 55658-71-4
- Chemical Name:
- HU-580
- Synonyms
- Cannabidiolic Acid methyl ester;HU-580;Cannabidiolinsaeure-methylester;Methyl 2,4-dihydroxy-3-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-6-pentylbenzoate;2,4-dihydroxy-3-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-6-pentyl-benzoic acid, methyl ester;Benzoic acid, 2,4-dihydroxy-3-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-6-pentyl-, methyl ester
- CBNumber:
- CB25822692
- Molecular Formula:
- C23H32O4
- Molecular Weight:
- 372.5
- MDL Number:
- MOL File:
- 55658-71-4.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| NFPA 704 |
|
HU-580 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28347 | Cannabidiolic Acid methyl ester ≥98% | 55658-71-4 | 1mg | $129 | 2026-04-30 | Buy |
| Cayman Chemical | 28347 | Cannabidiolic Acid methyl ester ≥98% | 55658-71-4 | 5mg | $510 | 2026-04-30 | Buy |
| Biosynth | FCA65871 | Methyl 2,4-dihydroxy-3-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-6-pentylbenzoate | 55658-71-4 | 5mg | $800.45 | 2026-06-04 | Buy |
| Biosynth | FCA65871 | Methyl 2,4-dihydroxy-3-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-6-pentylbenzoate | 55658-71-4 | 10mg | $1280.8 | 2026-06-04 | Buy |
| Biosynth | FCA65871 | Methyl 2,4-dihydroxy-3-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-6-pentylbenzoate | 55658-71-4 | 25mg | $2088.25 | 2026-06-04 | Buy |
HU-580 Chemical Properties, Uses, Production
Uses
Cannabidiolic acid methyl ester (HU-580) is an orally active cannabidiolic acid analogue. Cannabidiolic acid methyl ester can enhance the activation of 5-HT1A receptor and increase the expression of c-Fos and NeuN in specific hypothalamic nuclei of rats. Cannabidiolic acid methyl ester has anti-nausea, anti-anxiety and anti-injury effects[1][2][3].
IC 50
5-HT1A Receptor
References
[1] Pertwee RG, et al. Cannabidiolic acid methyl ester, a stable synthetic analogue of cannabidiolic acid, can produce 5-HT1A receptor-mediated suppression of nausea and anxiety in rats. Br J Pharmacol. 2018 Jan;175(1):100-112. DOI:10.1111/bph.14073
[2] Zhu YF, et al. An evaluation of the anti-hyperalgesic effects of cannabidiolic acid-methyl ester in a preclinical model of peripheral neuropathic pain. Br J Pharmacol. 2020 Jun;177(12):2712-2725. DOI:10.1111/bph.14997
[3] Murillo-Rodríguez E, et al.Assessing the treatment of cannabidiolic acid methyl ester: a stable synthetic analogue of cannabidiolic acid on c-Fos and NeuN expression in the hypothalamus of rats. J Cannabis Res. 2021 Jul 12;3(1):31. DOI:10.1186/s42238-021-00081-1
HU-580 Preparation Products And Raw materials
Raw materials
Preparation Products
HU-580 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Synchem Pharma Co., ltd | 21-619849051-1 18521059765 | synchempharma@aliyun.com | China | 4988 | 55 |
| Jinan Cen Ben Medical Technology Co., Ltd | 14793566 | info@cenpharm.com | China | 785 | 58 |
| TargetMol | 400-821-0310 15002144251 | xuexiang.shao@tsbiochem.com | China | 29128 | 58 |
| Guangzhou CATO Research Chemicals Inc. | +86-020-81960175-617 18520203721 | Intermediate@cato-chem.com | China | 3857 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Synchem Pharma Co., ltd | 55 |
| Jinan Cen Ben Medical Technology Co., Ltd | 58 |
| TargetMol | 58 |
| Guangzhou CATO Research Chemicals Inc. | 58 |
