13,14-dihydro-15-keto Prostaglandin D2-d9
- CAS No.
- 2738376-77-5
- Chemical Name:
- 13,14-dihydro-15-keto Prostaglandin D2-d9
- Synonyms
- 13,14-dihydro-15-keto Prostaglandin D2-d9
- CBNumber:
- CB26197281
- Molecular Formula:
- C20H23D9O5
- Molecular Weight:
- 361.52
- MDL Number:
- MOL File:
- 2738376-77-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS02 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| NFPA 704 |
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13,14-dihydro-15-keto Prostaglandin D2-d9 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 19334 | 13,14-dihydro-15-keto Prostaglandin D2-d9 ≥99%deuteratedforms(d1-d9) | 2738376-77-5 | 50μg | $193 | 2026-04-30 | Buy |
| Cayman Chemical | 19334 | 13,14-dihydro-15-keto Prostaglandin D2-d9 ≥99%deuteratedforms(d1-d9) | 2738376-77-5 | 100μg | $362 | 2026-04-30 | Buy |
13,14-dihydro-15-keto Prostaglandin D2-d9 Chemical Properties, Uses, Production
Uses
13,14-Dihydro-15-keto prostaglandin D2-d9 (DK-PGD2-d9) is deuterium labeled 13,14-Dihydro-15-keto prostaglandin D2. 13, 14-Dihydro-15-keto prostaglandin D2 (DK-PGD2) is a PGD2 metabolite formed by the 15-hydroxyl PGDH pathway. 13, 14-Dihydro-15-keto prostaglandin D2 is a selective agonist for the DP2 receptor. 13, 14-Dihydro-15-keto prostaglandin D2 can inhibit ion flux in canine colonic mucosa preparation[1][2].
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Larsen P, et al. Calcium-stimulated short-circuit currents in the canine proximal colonic epithelium: effects of DK-PGD2, a metabolite of prostaglandin D2. Can J Physiol Pharmacol. 2002 Nov;80(11):1085-94. DOI:10.1139/y02-139
[3] P K RANGACHARI P A B. Biological activity of metabolites of PGD2 on canine proximal colon.[J]. American Journal of Physiology, 1993, 264 5 Pt 1: G886-94. DOI: 10.1152/ajpgi.1993.264.5.g886
[4] H. HIRAI. Prostaglandin D2 Selectively Induces Chemotaxis in T Helper Type 2 Cells, Eosinophils, and Basophils via Seven-Transmembrane Receptor Crth2[J]. The Tokushima journal of experimental medicine, 2001, 1 1: 255-262. DOI: 10.1084/jem.193.2.255
[5] T E LISTON L J R. Metabolic fate of radiolabeled prostaglandin D2 in a normal human male volunteer.[J]. The Journal of Biological Chemistry, 1985, 260 24: 13172-13180.
[6] JASON D. MORROW. Quantification of the major urinary metabolite of prostaglandin D2 by a stable isotope dilution mass spectrometric assay[J]. Analytical biochemistry, 1991, 193 1: Pages 142-148. DOI: 10.1016/0003-2697(91)90054-w
13,14-dihydro-15-keto Prostaglandin D2-d9 Preparation Products And Raw materials
Raw materials
Preparation Products
13,14-dihydro-15-keto Prostaglandin D2-d9 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| CHINA ISOTOPE CO., LIMITED | 02151600108 13062666369 | info@isotopechem.com | China | 4721 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Supplier | Advantage |
|---|---|
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 58 |
| CHINA ISOTOPE CO., LIMITED | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
