Lithium tert-butoxide
- CAS No.
- 1907-33-1
- Chemical Name:
- Lithium tert-butoxide
- Synonyms
- LITHIUM T-BUTOXIDE;lithium 2-methylpropan-2-olate;LTB;LITHIUM TERT-BUTYLATE;Lithium tertiary butoxide;ithium tert-butoxide;Lithium 2-methyl-2-propanolate;TNFC;TNFSF3;400173-25G
- CBNumber:
- CB2663618
- Molecular Formula:
- C4H9LiO
- Molecular Weight:
- 80.05
- MDL Number:
- MFCD00050479
- MOL File:
- 1907-33-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | °C |
|---|---|
| Boiling point | 68-70 °C |
| Density | 0.89 g/mL at 20 °C |
| Flash point | −2 °F |
| storage temp. | 2-8°C |
| solubility | Soluble in toluene, hexane, tetrahydrofuran and methyl tert-butyl ether. |
| form | liquid |
| color | brown |
| Specific Gravity | 0.89 |
| Water Solubility | vigorous reaction |
| Sensitive | Moisture Sensitive |
| Hydrolytic Sensitivity | 7: reacts slowly with moisture/water |
| BRN | 3620018 |
| InChI | 1S/C4H9O.Li/c1-4(2,3)5;/h1-3H3;/q-1;+1 |
| InChIKey | LZWQNOHZMQIFBX-UHFFFAOYSA-N |
| SMILES | [Li+].CC(C)(C)[O-] |
| CAS DataBase Reference | 1907-33-1(CAS DataBase Reference) |
| EPA Substance Registry System | Lithium tert-butoxide (1907-33-1) |
| UNSPSC Code | 12352300 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H312-H412 | |||||||||
| Precautionary statements | P273-P280-P302+P352+P312-P362+P364-P501 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | F,C,N,T | |||||||||
| Risk Statements | 11-19-34-37-35-14-67-65-62-51/53-48/20-40-52/53-36/37/38-25 | |||||||||
| Safety Statements | 26-36/37/39-45-61-62-6A-43E-16-7/8-43-33 | |||||||||
| RIDADR | UN 3206 4.2/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UB8520000 | |||||||||
| F | 3-10 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 4.2 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29051990 | |||||||||
| Storage Class | 4.2 - Pyrophoric and self-heating hazardous materials | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Self-heat. 1 Skin Corr. 1B |
|||||||||
| REACH Registrations | Active | |||||||||
| Limited Quantities | 1.0 L (0.3 gallon) (liquid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
Lithium tert-butoxide price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 398195 | Lithium tert-butoxide solution 1.0 M in THF | 1907-33-1 | 50ml | $66.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | 398195 | Lithium tert-butoxide solution 1.0 M in THF | 1907-33-1 | 250ml | $227 | 2026-04-30 | Buy |
| Sigma-Aldrich | E8656 | Heat-Labile Enterotoxin, B subunit (LTB) from E. coli recombinant, expressed in Pichia pastoris, >90% (SDS-PAGE), lyophilized powder | 500 μg | $358.15 | 2025-07-31 | Buy | |
| Sigma-Aldrich | E8656 | Heat-Labile Enterotoxin, B subunit (LTB) from E. coli recombinant, expressed in Pichia pastoris, >90% (SDS-PAGE), lyophilized powder | 1907-33-1 | 500μg | $349 | 2024-03-01 | Buy |
| TCI Chemical | L0253 | Lithium tert-Butoxide (ca. 10% in Tetrahydrofuran, ca. 1mol/L) | 1907-33-1 | 100mL | $105 | 2026-04-30 | Buy |
Lithium tert-butoxide Chemical Properties, Uses, Production
Chemical Properties
Lithium tert-Butoxide [1907-33-1], LiOC (CH3)3, Mr 80.06, r 0.89 g/cm3, mp 283 ℃ is a colorless compound with good solubility in many organic solvents (e.g. 16 % in hexane). It is commercially available as min. 98 % powder and as a 20 % solution in THF. In organic synthesis it serves as a strong base. As one of the few volatile lithium compounds, it sublimes without decomposition at 110 ℃ in vacuum, and is therefore a suitable raw material for lithium doping in CVD processes.
Uses
Lithium tert-butoxide is a mild base used in organic synthesis. It is involved in the alfa-alkylation reaction of ketones with primary alcohols. It is utilized as a catalyst in the reduction of ketones to the corresponding secondary alcohols. It acts as lithium source utilized in the preparation of LixTiyOz thin films. Further, it is used in conjunction with organometallic reagents/catalysts to modify their reactivity and selectivity.
reaction suitability
core: lithium
Biochem/physiol Actions
Enterotoxigenic Escherichia coli causes diarrhea through its heat-labile enterotoxin (LT). The LT is a periplasmic protein composed of one A subunit (LTA, 27 kDa) and five non-covalently associated B subunits (LTB, 11.6 kDa each) forming a ring-like pentamer. LTB has high affinity towards the toxin receptor ganglioside GM1, a glycosphingolipid found ubiquitously on the surface of mammalian cells. Ganglioside GM1 facilitates the delivery of the A subunit to the cytosol of the target cell resulting in persistent synthesis of cAMP and subsequently diarrhea. This characteristic makes LTB a good label for microglial cells (due to the enrichment of ganglioside GM1 on their cell surface). In addition, studies made mostly with animal models demonstrated that recombinant LTB could stimulate strong serum and mucosal immune responses against LT. Other studies have indicated that LTB could be used as a potent mucosal adjuvant.
Safety
Lithium tert-butoxide is dangerous because it catches fire immediately in contact with air. A few precautions will reduce the risk: Use protection when handling hazardous chemicals, always wear lab coats and safety glasses; Because tert-butyl lithium will automatically react with atmospheric moisture, so avoid its exposure to the atmosphere; Don't work alone and remember how to handle an emergency.
Lithium tert-butoxide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| zibofeifanhuagong | 0533-18678146875 18678146875 | ziwenrong@163.com | China | 9 | 58 |
| SHANGHAI BANGCHENG CHEMICAL Co.,Ltd. | 021-69106960 13701823997 | 13701823733@163.com | China | 4634 | 60 |
| Shanghai Yihua Science and technology Co.,Ltd | 18017215653 | 1602230568@qq.com | China | 26 | 58 |
| Shanghai Rongli New Material Technology Co., Ltd. | 18019754112 | 477349526@qq.com | China | 20 | 58 |
| HuBei ShengWei New Material Co., Ltd. | 15207119892 15207119892 | 1558829227@qq.com | China | 158 | 58 |
| Lanzhou Hongsheng Fine Chemical Co., Ltd. | 15693160370; 15693160393 | lzhschemical@163.com | China | 58 | 58 |
| Shandong YingLang Chemical Co.,Ltd | 18266343295 | chen@chemwww.com | China | 4832 | 58 |
| Shanghai Huayu Industrial Co., Ltd. | 021-57468119 18917588395 | 3346096010@qq.com | China | 39 | 58 |
| Shandong Chenyi Environmental Protection Technology Co., Ltd | 1856-0179988 13355310698 | thezzc@outlook.com | China | 260 | 58 |
| Shanghai Haomuren New Materials Co., Ltd. | 15317828837 | 3759584103@qq.com | China | 43 | 58 |
Related articles
- Properties, Synthesis and Applications of Lithium tert-butoxide
- Lithium tert-butoxide is a widely used organometallic compound belonging to the class of alkali metal alkoxides.
- Jun 29,2026
View Latest Price from Lithium tert-butoxide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-28 | Lithium tert-butoxide
1907-33-1
|
$60.00 | 1KG | 99.9% | 100000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2025-06-27 | Lithium tert-butoxide
1907-33-1
|
1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2025-06-20 | Lithium tert-butoxide
1907-33-1
|
$1.00-10.00 | 1kg | 0.99 | 5 tons | Hebei Yanxi Chemical Co., Ltd. |
-
- Lithium tert-butoxide
1907-33-1
- $60.00
- 99.9%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- Lithium tert-butoxide
1907-33-1
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Lithium tert-butoxide
1907-33-1
- $1.00-10.00
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
