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Z-Ile-NH2

CAS No.
86161-49-1
Chemical Name:
Z-Ile-NH2
Synonyms
Z-Ile-NH?;Z-Ile-NH2;Z-L-Ile-NH2;Z-ISOLEUCINE-NH2;L-Z-IsoleucinaMide;Cbz-L-Isoleucinamide;Z-L-ISOLEUCINE AMIDE;Z-L-isoleucine amide99%;Z-(2S,3S)-2-amino-3-methylvaleric acid amide;N-ALPHA-CARBOBENZOXY-L-ISOLEUCINE ALPHA-AMIDE
CBNumber:
CB2699604
Molecular Formula:
C14H20N2O3
Molecular Weight:
264.32
MDL Number:
MFCD00238471
MOL File:
Mol file
MSDS File:
SDS
Last updated:2026-09-12 18:51:23

Z-Ile-NH2 Properties

Boiling point 461.5±38.0 °C(Predicted)
Density 1.124±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,2-8°C
pka 11.17±0.46(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338

Z-Ile-NH2 price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 280774 Z-L-isoleucine amide Asreported 86161-49-1 1g $340 2026-06-03 Buy
Usbiological 280774 Z-L-isoleucine amide Asreported 86161-49-1 2g $466 2026-06-03 Buy
Usbiological 280774 Z-L-isoleucine amide Asreported 86161-49-1 5g $712 2026-06-03 Buy
Usbiological 280774 Z-L-isoleucine amide Asreported 86161-49-1 10g $977 2026-06-03 Buy
Usbiological 280774 Z-L-isoleucine amide Asreported 86161-49-1 25g $1356 2026-06-03 Buy
Product number Packaging Price Buy
280774 1g $340 Buy
280774 2g $466 Buy
280774 5g $712 Buy
280774 10g $977 Buy
280774 25g $1356 Buy

Z-Ile-NH2 Chemical Properties, Uses, Production

Synthesis

N-Cbz-L-Isoleucine

3160-59-6

Pivaloyl chloride

3282-30-2

Z-ILE-NH2

86161-49-1

11-1) Preparation of benzyl (2S,3S)-(1-amino-3-methyl-1-oxopentan-2-yl)carbamate 2.63 g (10 mmol) of (2S,3S)-2-(((benzyloxy)carbonyl)amino)-3-methylpentanoic acid was added to a 100 mL solution of dichloromethane pre-cooled to -20°C. 1.40 mL of triethylamine and 1.23 mL of tertiary chloroyl chloride were added sequentially. after 30 min, an ammonia gas bulge was passed into the reaction mixture for 30 min. The resulting precipitate was filtered and the solid was washed with 50 mL of methylene chloride. The combined organic phases were washed sequentially with 2N HCl solution (50 mL x 2) and 50 mL saturated brine. The organic layer was dried with anhydrous MgSO4 and concentrated in vacuum to give 2.49 g (2S,3S)-(1-amino-3-methyl-1-oxopentan-2-yl)carbamic acid benzyl ester (yield: 95%). 1H NMR (CDCl3) δ: 0.9 (m, 6H), 1.2 (m, 1H), 1.5 (m, 1H), 1.8 (m, 1H), 4.0 (m, 1H), 5.1 (s, 2H), 6.5 (d, 1H).

References

[1] Patent: US5587388, 1996, A
[2] Patent: EP601486, 1994, A1

3160-59-6
3282-30-2
86161-49-1
Synthesis of Z-Ile-NH2 from N-Cbz-L-Isoleucine and Pivaloyl chloride

Z-Ile-NH2 Preparation Products And Raw materials

Z-Ile-NH2 Suppliers

Global Suppliers ( 19)
Supplier Tel Email Country ProdList Advantage
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56
Amatek Scientific Co. Ltd. 0512-56316828 400-867-5858;400-867-5858 info@amateksci.com China 28760 58
Nextpeptide Inc +86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19904 58
DONBOO AMINO ACID COMPANY 13063595538 donboo@donboo.com China 9358 58
TCI (Shanghai) Chemical Trading Co., Ltd. 021-61109150 sales@tcisct.com China 29717 58
Bide Pharmatech Ltd. 400-6005915 sales@picasso-e.com China 39645 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 17801761073 Gsiyu@solarbio.com China 50748 58
SHAANXI?DIDEU?MEDICHEM CO.LTD 17691182729 17392216275 1073@dideu.com China 9993 58
CarbaMic acid, [(1S,2S)-1-(aMinocarbonyl)-2-Methylbutyl]-, phenylMethyl ester L-Z-IsoleucinaMide Z-(2S,3S)-2-amino-3-methylpentanoic acid amide Z-(2S,3S)-2-amino-3-methylvaleric acid amide Z-L-Ile-NH2 Z-L-isoleucine amide99% N-ALPHA-CARBOBENZOXY-L-ISOLEUCINE ALPHA-AMIDE Z-ISOLEUCINE-NH2 Z-L-ISOLEUCINE AMIDE Cbz-L-Isoleucinamide (2S,3S)-Benzyl (1-amino-3-methyl-1-oxopentan-2-yl)carbamate Z-Ile-NH? Carbamic acid, [(1S,2S)-1-(aminocarbonyl)-2-methylbutyl]-, phenylmethyl ester (9CI) Z-Ile-NH2 86161-49-1