5-Nitrofurfural
- CAS No.
- 698-63-5
- Chemical Name:
- 5-Nitrofurfural
- Synonyms
- 5-NITRO-2-FURALDEHYDE;AKOS B004244;Nitrofurfural;5-Nitrofurural;5-nitro-furfura;5-NITROFURFURAL;Furfural, 5-nitro-;5-NITROFURALDEHYDE;Niftyer Impurity 7;Nitrofuraldehyde,97%
- CBNumber:
- CB2711562
- Molecular Formula:
- C5H3NO4
- Molecular Weight:
- 141.08
- MDL Number:
- MFCD00003230
- MOL File:
- 698-63-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 5-Nitro-2-furaldehyde 99% | 170968 | 5g | $93.3 |
| 5-Nitro-2-furaldehyde 99% | 170968 | 25g | $179 |
| 5-Nitro-2-furaldehyde >98.0%(GC) | N0387 | 5g | $37 |
| 5-Nitro-2-furaldehyde >98.0%(GC) | N0387 | 25g | $105 |
| 5-Nitro-2-furaldehyde | 436973 | 1g | $326 |
| More product size | |||
| Melting point | 37-39 °C(lit.) |
|---|---|
| Boiling point | 121 °C10 mm Hg(lit.) |
| Density | 1.349 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 92 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly) |
| form | Crystalline Low Melting Solid |
| color | Yellow to brown |
| Water Solubility | sparingly soluble |
| Sensitive | Air & Light Sensitive |
| BRN | 120539 |
| InChI | 1S/C5H3NO4/c7-3-4-1-2-5(10-4)6(8)9/h1-3H |
| InChIKey | SXINBFXPADXIEY-UHFFFAOYSA-N |
| SMILES | [H]C(=O)c1ccc(o1)[N+]([O-])=O |
| CAS DataBase Reference | 698-63-5(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | XXX18AU0Z3 |
| NIST Chemistry Reference | 2-Furancarboxaldehyde, 5-nitro-(698-63-5) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H228 | |||||||||
| Precautionary statements | P210 | |||||||||
| PPE | Eyeshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | F,Xi,Xn | |||||||||
| Risk Statements | 11-68-10 | |||||||||
| Safety Statements | 16-36/37 | |||||||||
| RIDADR | UN 1325 4.1/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LT7200000 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 3.2 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29321900 | |||||||||
| Storage Class | 4.1B - Flammable solid hazardous materials | |||||||||
| Hazard Classifications | Flam. Sol. 1 | |||||||||
| Hazardous Substances Data | 698-63-5(Hazardous Substances Data) | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
5-Nitrofurfural price More Price(68)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 170968 | 5-Nitro-2-furaldehyde 99% | 698-63-5 | 5g | $93.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | 170968 | 5-Nitro-2-furaldehyde 99% | 698-63-5 | 25g | $179 | 2026-04-30 | Buy |
| TCI Chemical | N0387 | 5-Nitro-2-furaldehyde >98.0%(GC) | 698-63-5 | 5g | $37 | 2026-04-30 | Buy |
| TCI Chemical | N0387 | 5-Nitro-2-furaldehyde >98.0%(GC) | 698-63-5 | 25g | $105 | 2026-04-30 | Buy |
| Usbiological | 436973 | 5-Nitro-2-furaldehyde | 698-63-5 | 1g | $326 | 2026-06-03 | Buy |
5-Nitrofurfural Chemical Properties,Uses,Production
Description
Nitrofuran carboxaldehyde (NFC) is used to synthesize many drugs and chemicals such as nifuraldezone, puraguanidine, nifuratrone, furmethoxadone, etc. Furfural the main structure of NFC was determined many years ago to be a byproduct of formic acid synthesis. Furfural is produced from agricultural byproducts such as sugarcane bagasse and corncobs.
Chemical Properties
Yellow to brown crystalline low melting solid
Uses
NFC and its derivatives have antibacterial and antifungal activities. They destroy both gram-positive and gram-negative organisms such as Staphylococcus aureus, Salmonella schotmuelleri, Pseudomonas aeruginosa, Proteus vulgaris, Escherichia coli, and Streptococcus pyogenes. They may be used as antibacterial agents in a prophylactic manner, for example, in cleaning and disinfecting products. This compound also has antitrichomonal and antifungal activities.
Uses
5-Nitro-2-furaldehyde was used in the synthesis of a series of 4-(5-nitrofuran-2-yl)prop-2-en-1-one derivatives. . It was also used in the synthesis of modified mesoporous silica (MCM-41). 5-Nitrofurfural can be commonly used as pharmaceutical intermediates.
Definition
ChEBI: 5-Nitrofurfural is a C-nitro compound and a member of furans.
Production Methods
Furfural is nitrated in acetic anhydride solution at 25 – 40 ℃ to give the diacetate [92-55-7], which is purified by recrystallization from isopropanol and then used directly for the production of derived drugs.
Toxicity evaluation
NFC inhibits the uptake of oxygen and disrupts cellular respiration within mitochondria. NFC and other nitrofurans are relatively potent inhibitors of monoamine oxidase enzyme in mammalian and avian species.
References
[1] Chemistry - A European Journal, 2010, vol. 16, # 42, p. 12718 - 12726
[2] Patent: CN108101874, 2018, A. Location in patent: Paragraph 0006; 0017; 0020; 0023; 0026; 0028; 0031
[3] RSC Advances, 2014, vol. 4, # 25, p. 12834 - 12839
[4] Journal of the American Chemical Society, 1931, vol. 53, p. 1923
[5] Green Chemistry, 2017, vol. 19, # 5, p. 1315 - 1326
5-Nitrofurfural Preparation Products And Raw materials
Raw materials
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Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2165 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 9542 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
View Lastest Price from 5-Nitrofurfural manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-09-02 | 5-Nitrofurfural
698-63-5
|
$7.00 | 1KG | 99% | Career Henan Chemical Co | ||
 |
2019-09-02 | 5-Nitrofurfural
698-63-5
|
$7.00 | 1KG | 99% | Career Henan Chemical Co |
-
- 5-Nitrofurfural
698-63-5
- $7.00
- 99%
- Career Henan Chemical Co
-
- 5-Nitrofurfural
698-63-5
- $7.00
- 99%
- Career Henan Chemical Co
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