ChemicalBook >> CAS DataBase List >>Sennoside B
Sennoside B
- CAS No.
- 128-57-4
- Chemical Name:
- Sennoside B
- Synonyms
- Tisasen B;PURSENNIDE;GLYSENNIDE;SENNOSIDE B;SENNOSIDE B(P);Sennoside B RS;SENNIDINE B(RG);SENNOSIDE B(SH);Sennoside B(AS);SENNOSIDE B hplc
- CBNumber:
- CB2728337
- Molecular Formula:
- C42H38O20
- Molecular Weight:
- 862.74
- MDL Number:
- MFCD00151528
- MOL File:
- 128-57-4.mol
Last updated:2025-09-30 18:11:34
| Melting point | 209～212℃ |
|---|---|
| alpha | D20 -100° (c = 0.2 in 70% acetone); D20 -67° (c = 0.4 in 70% dioxane) |
| Boiling point | 698.48°C (rough estimate) |
| Density | 1.3066 (rough estimate) |
| refractive index | 1.7630 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO (Very Slightly, Heated), Methanol (Slightly, Heated) |
| pka | 3.31±0.40(Predicted) |
| form | Solid |
| color | Light Yellow to Dark Yellow |
| BRN | 5723747 |
| Stability | Hygroscopic |
| InChIKey | IPQVTOJGNYVQEO-IDJKMNDUNA-N |
| LogP | 1.880 (est) |
| CAS DataBase Reference | 128-57-4(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | F887D1637W |
| UNSPSC Code | 85151701 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 22-45-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29329990 | |||||||||
| NFPA 704 |
|
Sennoside B price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 1612029 | Sennoside B United States Pharmacopeia (USP) Reference Standard | 128-57-4 | 20mg | $576 | 2025-07-31 | Buy |
| Sigma-Aldrich | 00530580 | Sennoside B primary reference standard | 128-57-4 | 25 mg | $650 | 2025-07-31 | Buy |
| Sigma-Aldrich | 75412 | Sennoside B analytical standard | 128-57-4 | 25mg | $241 | 2022-05-15 | Buy |
| TCI Chemical | E1546 | Sennoside B | 128-57-4 | 100MG | $240 | 2025-07-31 | Buy |
| Cayman Chemical | 28410 | Sennoside B | 128-57-4 | 10mg | $63 | 2024-03-01 | Buy |
Sennoside B Chemical Properties,Uses,Production
Chemical Properties
White to brown powder
Uses
Sennoside B is used in the inhibition of platelet driven growth factor (PDGF) used and may inhibit proliferative disease which depend upon the PDGF pathway. Laxative.
Definition
ChEBI: A member of the class of sennosides that is (9R,9'S)-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid which is substituted by hydroxy groups at positions 4 and 4', by beta-D glucopyranosyloxy groups at positions 5 and 5', and by oxo groups at positions 10 and 10'.
in vivo
Sennoside B (100 mg/kg; p.o.) shows gastroprotective activities by reducing lesion indices in HCl?EtOH and Indomethacin (HY-14397) induces gastritis in rats[1].
| Animal Model: | 170-200g, Male Sprague-Dawley rats (HCl?EtOH-induced gastritis)[1] |
| Dosage: | 100 mg/kg |
| Administration: | P.o. |
| Result: | Reduced lesion indices to 60.8 ± 18.4 mm, by inhibition rate of 39.9%. |
Purification Methods
Sennoside B forms yellow crystals from aqueous acetone or large volumes of H2O. [Stoll et al. Helv Chim Acta 32 1896 1900, Beilstein 17 III/IV 3402.]
Sennoside B Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 336)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 | info@binbobiological.com | China | 453 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29852 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2930 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3751 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
View Lastest Price from Sennoside B manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-30 | Sennoside B
128-57-4
|
US $0.00 / removed | 97.35% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-09-29 | Sennoside B; Senna leaf extract
128-57-4
|
US $0.00 / MG | 20MG | 95%-99% HPLC | 1000KG | Changsha Staherb Natural Ingredients Co., Ltd. | |
 |
2025-06-13 | Sennoside B
128-57-4
|
US $0.00 / kg | 1kg | 99.8% | 1000 kg | BINBO BIOLOGICAL CO.,LTD |
-
- Sennoside B
128-57-4
- US $0.00 / removed
- 97.35%
- TargetMol Chemicals Inc.
-
- Sennoside B; Senna leaf extract
128-57-4
- US $0.00 / MG
- 95%-99% HPLC
- Changsha Staherb Natural Ingredients Co., Ltd.
-
- Sennoside B
128-57-4
- US $0.00 / kg
- 99.8%
- BINBO BIOLOGICAL CO.,LTD
128-57-4(Sennoside B)Related Search:
CHLOROPHOSPHONAZO III
Sennoside D
SENNOSIDE A(SH),SENNOSIDE A(P),SENNOSIDE,CALCIUM SENNOSIDE 5%, 10%, 20%, 60%,Sennoside A std.,SENNOSIDE A hplc,SENNOSIDE A WITH HPLC,Sennoside A1,SENNOSIDE A
Sennoside C
SENNIDINE A
1of4
PURSENNIDE
SENNOSIDE B 96.5+%
Sennoside B std.
9,9-Bianthracene-2,2-dicarboxylic acid, 5,5-bis(.beta.-D-glucopyranosyloxy)-9,9,10,10-tetrahydro-4,4-dihydroxy-10,10-dioxo-, (9R,9S)-
(9S)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid
SENNIDINE B(RG)
SENNOSIDE B(P)
SENNOSIDE B(SH)
SENNOSIDE B hplc
SENNOSIDE B WITH HPLC
Sennoside B, 98%, from Folium sennae
[9,9'-Bianthracene]-2,2'-dicarboxylicacid,5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-,(9R,9'S)-
N,N-dimethyl-4-[(E,3Z)-3-(2-nitro-9-fluorenylidene)prop-1-enyl]aniline
(9R,9'S)-5,5'-Bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-9,9'-bianthracene-2,2'-dicarboxylic acid
(9S,9'R)-5,5'-Bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-9,9'-bianthracene-2,2'-dicarboxylic acid
(9S)-9-[(9R)-2-carboxy-4-hydroxy-10-keto-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-keto-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-9H-anthracene-2-carboxylic acid
Sennoside B ,98%
Tisasen B
(9R,9'S)-4,4'-dihydroxy-10,10'-dioxo-5,5'-bis(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyMethyl)tetrahydro-2H-pyran-2-yl)oxy)-9,9',10,10'-tetrahydro-[9,9'-bianthracene]-2,2'-dicarboxylic acid
Sennoside B, froM FoliuM sennae
Sennoside B (20 mg)
GLYSENNIDE
(9S)-9-[(9R)-2-Carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid
SENNOSIDE B
Sennoside B Standard
Sennoside B RS
Sennoside B(AS)
Sennoside B, 10 mM in DMSO
128-57-4
C42H38O20
SA - SM
Alphabetic
Analytical Standards
Analytical Chromatography Product Catalog
The group of Sennosides
Anthraquinones, Hydroquinones and Quinones
chemical reagent
pharmaceutical intermediate
phytochemical
reference standards from Chinese medicinal herbs (TCM).
standardized herbal extract
Inhibitors
