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3-Amino-2-bromopyridine

CAS No.
39856-58-1
Chemical Name:
3-Amino-2-bromopyridine
Synonyms
TIMTEC-BB SBB005539;3-Amino-2-bromopyrid;2-BROMO-PYRIDINEAMINE;2-bromopyridin-3-amine;2-Bromo-3-pyridinamine;2-BROMO-3-PYRIDINEAMINE;2-BROMOPYRIDINE-3-AMINE;2-BROMO-3-AMINOPYRIDINE;3-AMINO-2-BROMOPYRIDINE;3-Pyridinamine, 2-bromo-
CBNumber:
CB2730581
Molecular Formula:
C5H5BrN2
Molecular Weight:
173.01
MDL Number:
MFCD00234064
MOL File:
39856-58-1.mol
Last updated:2026-01-13 11:17:18
Product description Number Pack Size Price
3-Amino-2-bromopyridine 97% 661228 1g $33.47
3-Amino-2-bromopyridine >98.0%(GC)(T) A1898 1g $33
3-Amino-2-bromopyridine >98.0%(GC)(T) A1898 5g $102
3-Amino-2-bromopyridine A602123 50mg $60
3-Amino-2-bromopyridine A602123 10mg $45
More product size

3-Amino-2-bromopyridine Properties

Melting point 76-80 °C
Boiling point 292.5±20.0 °C(Predicted)
Density 1.710±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka 1.72±0.10(Predicted)
form Crystalline Powder
color Beige to dark brown
Water Solubility Slightly soluble in water.
BRN 109830
InChI 1S/C5H5BrN2/c6-5-4(7)2-1-3-8-5/h1-3H,7H2
InChIKey HKDVVTLISGIPFE-UHFFFAOYSA-N
SMILES Nc1cccnc1Br
CAS DataBase Reference 39856-58-1(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS06
Signal word  Danger
Hazard statements  H301-H315-H318-H335
Precautionary statements  P280-P301+P310+P330-P302+P352-P305+P351+P338+P310
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xn,Xi
Risk Statements  22-37/38-41-36/37/38
Safety Statements  26-36/39-37/39
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
HazardClass  IRRITANT
PackingGroup  III
HS Code  29333990
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3
NFPA 704
1
3 0

3-Amino-2-bromopyridine price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 661228 3-Amino-2-bromopyridine 97% 39856-58-1 1g $33.47 2025-07-31 Buy
TCI Chemical A1898 3-Amino-2-bromopyridine >98.0%(GC)(T) 39856-58-1 1g $33 2025-07-31 Buy
TCI Chemical A1898 3-Amino-2-bromopyridine >98.0%(GC)(T) 39856-58-1 5g $102 2025-07-31 Buy
TRC A602123 3-Amino-2-bromopyridine 39856-58-1 50mg $60 2021-12-16 Buy
TRC A602123 3-Amino-2-bromopyridine 39856-58-1 10mg $45 2021-12-16 Buy
Product number Packaging Price Buy
661228 1g $33.47 Buy
A1898 1g $33 Buy
A1898 5g $102 Buy
A602123 50mg $60 Buy
A602123 10mg $45 Buy

3-Amino-2-bromopyridine Chemical Properties,Uses,Production

Chemical Properties

Light yellow Cryst

Uses

Used in a palladium-catalyzed synthesis of indole systems containing fused medium- and large-ring heterocycles. pyrrole derivatives ahs been prepared using 3-Amino-2-bromopyridine. Used in P-C coupling reaction.

Synthesis

2-Bromo-3-nitropyridine

19755-53-4

3-Amino-2-bromopyridine

39856-58-1

Preparation of Example S-1: 2-Bromo-3-nitropyridine (3 g, 15 mmol) was dissolved in a solvent mixture of tetrahydrofuran (15 mL) and water (5 mL), followed by the addition of iron powder (1 g, 18 mmol) and ammonium chloride (2 g, 37 mmol). The reaction mixture was stirred at 60°C to 70°C for 5 hours. Upon completion of the reaction, the reaction mixture was filtered through a diatomaceous earth pad and the filtrate was washed with brine and extracted with ethyl acetate. The organic layers were combined, dried with anhydrous magnesium sulfate and concentrated under reduced pressure. The resulting crude product was purified by silica gel column chromatography (eluent: ethyl acetate/hexane=1:4) to afford 2-bromo-3-aminopyridine (2.6 g, 15 mmol, quantitative yield).1H-NMR (DMSO-d6) δ (ppm): 5.47 (2H, brs), 7.07-7.09 (2H, m), 7.54 (1H, dd, J=). 2.0,3.6Hz).

References

[1] Patent: EP1782811, 2007, A1. Location in patent: Page/Page column 63
[2] Patent: EP1669348, 2006, A1. Location in patent: Page/Page column 71
[3] Bulletin de la Societe Chimique de France, 1992, # 1, p. 79 - 84
[4] Journal of the Chemical Society, 1952, p. 2042,2044
[5] Tetrahedron, 2002, vol. 58, # 17, p. 3323 - 3328

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View Lastest Price from 3-Amino-2-bromopyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Amino-2-bromopyridine pictures 2025-06-25 3-Amino-2-bromopyridine
39856-58-1
US $21.00 / KG 1KG 99.0% min 100 tons Shaanxi Dideu Medichem Co. Ltd
3-Amino-2-bromopyridine pictures 2025-06-25 3-Amino-2-bromopyridine
39856-58-1
US $1.10 / g 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
3-Amino-2-bromopyridine pictures 2025-04-04 3-Amino-2-bromopyridine
39856-58-1
US $0.00-0.00 / kg 1kg 98% 10Ton Henan Aochuang Chemical Co.,Ltd.
3-Amino-2-bromopyridine 97% 2-BROMO-3-AMINOPYRIDINE 2-BROMOPYRIDINE-3-AMINE 2-BROMO-PYRIDINEAMINE 2-BROMO-PYRIDIN-3-YLAMINE 3-AMINO-2-BROMOPYRIDINE TIMTEC-BB SBB005539 2-BROMO-3-AMINOPYRIDINE,98+% 2-BROMO-3-PYRIDINEAMINE 2-Bromo-3-pyridinamine 2-bromopyridin-3-amine 3-Amino-2-bromopyridine,97% 2-bromo-1H-pyridin-2-amine 3-Amino-2-bromopyrid 3-Amino-2-bromopyridine > 3-Pyridinamine, 2-bromo- 3-Amino-2-bromopyridine ISO 9001:2015 REACH 2-bromo-3-pyridineamine 98% 39856-58-1 C5H5BrN2 Bromopyridines Halopyridines Building Blocks Heterocyclic Building Blocks Halogenated Heterocycles Pyridines C5Heterocyclic Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Amino-pyridine series Pyridine series Amines Pyridines Pyridine Bromopyridines Halopyridines