Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2-Chloro-4-nitropyridine

2-Chloro-4-nitropyridine

2-Chloro-4-nitropyridine Structure
2-Chloro-4-nitropyridine structure
CAS No.
23056-36-2
Chemical Name:
2-Chloro-4-nitropyridine
Synonyms
2-Chl;AURORA 23245;AKOS BBS-00001358;2-Chloro-4-nitropyri;OTAVA-BB BB7017520053;2-chloro-4-nitropyrine;2-Choro-4-nitropyridine;2-CHLORO-4-NITROPYRIDINE;4-Nitro-2-chloropyridine;oro-4-nitropyridine, 98%
CBNumber:
CB2737111
Molecular Formula:
C5H3ClN2O2
Molecular Weight:
158.54
MDL Number:
MFCD00661454
MOL File:
23056-36-2.mol
Last updated:2025-07-24 18:13:49
Product description Number Pack Size Price
2-Chloro-4-nitropyridine 97% 557390 5g $56.7
2-Chloro-4-nitropyridine 97% 557390 1g $25
2-Chloro-4-nitropyridine >98.0%(GC) C2283 1g $37
2-Chloro-4-nitropyridine >98.0%(GC) C2283 5g $101
2-Chloro-4-nitropyridine >98.0%(GC) C2283 25g $343
More product size
Request For Quotation

2-Chloro-4-nitropyridine Properties

Melting point 52-56 °C (lit.)
Boiling point 258.4±20.0 °C(Predicted)
Density 1.489±0.06 g/cm3(Predicted)
Flash point 223 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka -1.93±0.10(Predicted)
form crystalline powder
color Yellow
BRN 120418
InChI InChI=1S/C5H3ClN2O2/c6-5-3-4(8(9)10)1-2-7-5/h1-3H
InChIKey LIEPVGBDUYKPLC-UHFFFAOYSA-N
SMILES C1(Cl)=NC=CC([N+]([O-])=O)=C1
CAS DataBase Reference 23056-36-2(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-36/37/38
Safety Statements  26-36
WGK Germany  3
HazardClass  IRRITANT
PackingGroup  III
HS Code  29333990
NFPA 704
1
2 0

2-Chloro-4-nitropyridine price More Price(51)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 557390 2-Chloro-4-nitropyridine 97% 23056-36-2 5g $56.7 2025-07-31 Buy
Sigma-Aldrich 557390 2-Chloro-4-nitropyridine 97% 23056-36-2 1g $25 2023-06-20 Buy
TCI Chemical C2283 2-Chloro-4-nitropyridine >98.0%(GC) 23056-36-2 1g $37 2025-07-31 Buy
TCI Chemical C2283 2-Chloro-4-nitropyridine >98.0%(GC) 23056-36-2 5g $101 2025-07-31 Buy
TCI Chemical C2283 2-Chloro-4-nitropyridine >98.0%(GC) 23056-36-2 25g $343 2025-07-31 Buy
Product number Packaging Price Buy
557390 5g $56.7 Buy
557390 1g $25 Buy
C2283 1g $37 Buy
C2283 5g $101 Buy
C2283 25g $343 Buy

2-Chloro-4-nitropyridine Chemical Properties,Uses,Production

Chemical Properties

Light yellow powder

Uses

2-Chloro-4-nitropyridine is used in the preparation of (thio)barbituric acid derivatives in the treatment of obesity related non-alcoholic fatty liver disease. As well it is used in the production of selective and potent MET Kinase inhibitors.

Uses

2-Chloro-4-nitropyridine may be used to synthesize 2-chloro-4-ethoxypyridine and 4-thiophenoxypyridines.

Synthesis

2-Chloro-4-nitropyridine 1-oxide

14432-16-7

2-Chloro-4-nitropyridine

23056-36-2

The general procedure for the synthesis of 2-chloro-4-nitropyridine-N-oxide from 2-chloro-4-nitropyridine-N-oxide is as follows: referring to the method of Example 17, phosphorus trichloride (4.2 mL, 48.7 mmol) was slowly added to a solution of anhydrous chloroform (25 mL) of 2-chloro-4-nitropyridine-N-oxide (1.70 g, 9.74 mmol) at room temperature. Subsequently, the reaction mixture was heated to reflux and maintained at this temperature for the reaction overnight. Upon completion of the reaction, the mixture was cooled to room temperature. The reaction solution was carefully poured into ice water and the pH was adjusted to 7-8 with alkali and subsequently washed with saturated sodium bicarbonate solution. The aqueous phase was extracted twice with chloroform, all organic phases were combined, washed sequentially with water and brine, dried over anhydrous sodium sulfate, filtered and the organic phase was concentrated. Finally, the product was dried under high vacuum to give 2-chloro-4-nitropyridine (1.2 g, 78% yield) as a solid.

References

[1] Journal of Organic Chemistry, 2009, vol. 74, # 19, p. 7441 - 7448
[2] Patent: WO2008/62182, 2008, A1. Location in patent: Page/Page column 114
[3] Journal of the American Chemical Society, 1959, vol. 81, p. 2674

2-Chloro-4-nitropyridine synthesis

14432-16-7
23056-36-2
Synthesis of 2-Chloro-4-nitropyridine from 2-Chloro-4-nitropyridine 1-oxide

2-Chloro-4-nitropyridine Preparation Products And Raw materials

Raw materials

Hydrogen peroxide Phosphorus oxitrichloride Nitric acid Acetic acid Sulfuric acid
2-Chloropyridine 4-Nitropyridine N-oxide Phosphorus trichloride 2-Chloro-4-nitropyridine 1-oxide 2-Chloropyridine-N-oxide

1of2

Preparation Products

2-Chloro-4-hydroxypyridine 4-Bromo-2-methylpyridine 4-Nitro-2-phenylpyridine

2-Chloro-4-nitropyridine Suppliers

Global( 438)Suppliers
Supplier Tel Email Country ProdList Advantage
Anhui Ruihan Technology Co., Ltd 		+8617756083858 daisy@anhuiruihan.com China 973 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29735 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29843 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10405 58
HaBo Hong Kong Co., Limited. 		+86-25-18512596065 info@habotech.com CHINA 933 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
BTC Nantong Pharmaceuticals Technology Co.,Ltd 		+8618068193575 sales4@btcpharm.com China 251 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10821 58
Supplier Advantage
Anhui Ruihan Technology Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
HaBo Hong Kong Co., Limited. 		58
Hubei Jusheng Technology Co.,Ltd. 		58
BTC Nantong Pharmaceuticals Technology Co.,Ltd 		58
Alchem Pharmtech,Inc. 		58
Wuhan Chemwish Technology Co., Ltd 		58

View Lastest Price from 2-Chloro-4-nitropyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloro-4-nitropyridine pictures 2025-11-18 2-Chloro-4-nitropyridine
23056-36-2
 US $1.10 / g 1g 99.00% 100 Tons min Dideu Industries Group Limited
2-Chloro-4-nitropyridine pictures 2025-04-04 2-Chloro-4-nitropyridine
23056-36-2
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
2-Chloro-4-nitropyridine pictures 2024-02-26 2-Chloro-4-nitropyridine
23056-36-2
 US $0.00-0.00 / kg 1kg 98% Kgs BTC Nantong Pharmaceuticals Technology Co.,Ltd

2-Chloro-4-nitropyridine Spectrum

2-Chloro-4-nitropyridine(23056-36-2)1HNMR2-Chloro-4-nitropyridine(23056-36-2)IR

23056-36-2(2-Chloro-4-nitropyridine)Related Search:

2-Bromo-5-nitropyridine 4-Nitropyridine Pentachloropyridine 1-Chloro-3-nitrobenzene 2-Chloro-5-chloromethylpyridine
2-Chloro-3-hydroxypyridine Clopidol 2-Chloro-4-picoline 4-Chloronitrobenzene Difluorochloromethane
2-CHLORO-3-FLUORO-4-NITROPYRIDINE N-OXIDE 2,6-Dichloro-3-nitropyridine 2,6-DICHLORO-4-NITROPYRIDINE-N-OXIDE 2-CHLORO-4-NITROPYRIDINE-N-OXIDE,2-CHLORO-4-NITROPYRIDINE 1-OXIDE,2-Chloro-4-nitropyridine-N-oxide ,97% 4-Nitrobenzyl chloride
2,4-Dichloro-3-nitropyridine 4-Chloro-3-nitropyridine hydrochloride, 97+%,4-Chloro-3-nitropyridine hydrochloride, 98+%,4-CHLORO-3-NITROPYRIDINE HYDROCHLORIDE, 90+% 2-Nitrochlorobenzene

1of4

OTAVA-BB BB7017520053 2-CHLORO-4-NITROPYRIDINE (2-CHLOROPYRIDIN-4-YL)(HYDROXY)OXOAMMONIUM AURORA 23245 AKOS BBS-00001358 2-chloro-4-nitropyrine 2-Chloro-4-nitropyridine ,98% 2-Chloro-4-nitropyri JRH-09201, 2-Chloro-4-nitropyridine, 97% 2-Choro-4-nitropyridine 2-Chl 4-Nitro-2-chloropyridine 2-Chloro-4-nitropyridine > oro-4-nitropyridine, 98% Pyridine, 2-chloro-4-nitro- 2,5-Difluoro-6-iodopyridine 2-Chloro-4-nitropyridine ISO 9001：2015 REACH 23056-36-2 Building Blocks Pyridines Heterocyclic Building Blocks Halogenated Heterocycles pyridine series C5Heterocyclic Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Pyridines Pyridine Derivertives Pyridine