Norgestrel
- CAS No.
- 6533-00-2
- Chemical Name:
- Norgestrel
- Synonyms
- Levonorgestrel-D6;D-NORGESTREL;sh850;wy3707;sh70850;monovar;Neogest;Ovrette;fh122-a;NORPLANT
- CBNumber:
- CB2752440
- Molecular Formula:
- C21H28O2
- Molecular Weight:
- 312.45
- MDL Number:
- MFCD01546387
- MOL File:
- 6533-00-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Norgestrel Pharmaceutical Secondary Standard; Certified Reference Material | PHR2487 | 200MG | $295 |
| Norgestrel European Pharmacopoeia (EP) Reference Standard | N1250000 | 30 mg | $241 |
| Norgestrel British Pharmacopoeia (BP) Reference Standard | BP714 | 100 mg | $339 |
| Norgestrel | 1472000 | 125mg | $360 |
| Norgestrel European Pharmacopoeia (EP) Reference Standard | N1250000 | n1250000 | $220 |
| More product size | |||
| Melting point | 239-241 °C(lit.) |
|---|---|
| Boiling point | 392.36°C (rough estimate) |
| Density | 1.0697 (rough estimate) |
| refractive index | 1.4900 (estimate) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly, Sonicated), Dichloromethane (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 13.09±0.40(Predicted) |
| color | Crystals from diethyl ether-hexane |
| Henry's Law Constant | 1.3×104 mol/(m3Pa) at 25℃, HSDB (2015) |
| Exposure limits | PC-TWA: 0.5 mg/m3; PC-STEL: 2 mg/m3 |
| InChI | InChI=1/C21H28O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,13,16-19,23H,3,5-12H2,1H3/t16-,17+,18+,19-,20-,21-/s3 |
| InChIKey | WWYNJERNGUHSAO-XUDSTZEESA-N |
| SMILES | [C@]12(CC)CC[C@]3([H])[C@@]4([H])CCC(=O)C=C4CC[C@@]3([H])[C@]1([H])CC[C@@]2(O)C#C |&1:0,5,7,17,19,23,r| |
| CAS DataBase Reference | 6533-00-2(CAS DataBase Reference) |
| FDA UNII | 3J8Q1747Z2 |
| Proposition 65 List | Norgestrel |
| NCI Drug Dictionary | Norplant |
| EPA Substance Registry System | Norgestrel (6533-00-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H319-H360FD | |||||||||
| Precautionary statements | P202-P264-P280-P302+P352-P305+P351+P338-P308+P313 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-40 | |||||||||
| Safety Statements | 22-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | JF8259000 | |||||||||
| HS Code | 2937230000 | |||||||||
| Hazardous Substances Data | 6533-00-2(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 oral in rat: 5010mg/kg | |||||||||
| NFPA 704 |
|
Norgestrel price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR2487 | Norgestrel Pharmaceutical Secondary Standard; Certified Reference Material | 6533-00-2 | 200MG | $295 | 2026-04-30 | Buy |
| Sigma-Aldrich | N1250000 | Norgestrel European Pharmacopoeia (EP) Reference Standard | 6533-00-2 | 30 mg | $241 | 2026-04-30 | Buy |
| Sigma-Aldrich | BP714 | Norgestrel British Pharmacopoeia (BP) Reference Standard | 6533-00-2 | 100 mg | $339 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1472000 | Norgestrel | 6533-00-2 | 125mg | $360 | 2026-04-30 | Buy |
| Sigma-Aldrich | N1250000 | Norgestrel European Pharmacopoeia (EP) Reference Standard | 6533-00-2 | n1250000 | $220 | 2024-03-01 | Buy |
Norgestrel Chemical Properties,Uses,Production
Description
Norgestrel is a synthetic progestin and a racemic mixture of dextronorgestrel and levonorgestrel , of which levonorgestrel is the biologically active component. In vivo, norgestrel administered via intrauterine device (IUD) prevents pregnancy in rats. Formulations containing nogestrel have been used as contraceptives.
Chemical Properties
White Solid
Uses
Progestogen; oral contraceptive. The bioactive enantiomer is levorotatory
Uses
A metabolite of Norgestrel.
Uses
Protected D-(-)-Norgestrel
Uses
A glucuronide metabolite of Levonorgestrel.
Uses
An intermediate to the glucuronide metabolite of Levonorgestrel.
Uses
It is an excellent progestational and ovulation inhibiting steroid. The bioactive enantiomer is levorotatory. Progestogen; oral contraceptive.
Uses
analgesic, antipyretic
Definition
ChEBI: Levonorgestrel is a 17beta-hydroxy steroid, a 3-oxo-Delta(4) steroid and a terminal acetylenic compound. It has a role as a contraceptive drug, a progestin, a synthetic oral contraceptive and a female contraceptive drug. It is functionally related to a norgestrel. It is an enantiomer of a dexonorgestrel.
brand name
Ovrette (Wyeth).
General Description
Norgestrel, (17α)-(±)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one, and levonorgestrel, (17α)-(-)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one,have a C13 ethyl group instead of the C13 methyl but haveprogestational properties similar to those of norethindrone,with decreased androgenic effects. The ethyl group apparentlyprovides unfavorable steric interactions with the ARthat reduce the affinity compared with that with the PRs.Norgestrel is a racemic mixture, while levonorgestrel is thesingle active levorotatory enantiomer. Norgestrel is usedonly in oral contraceptives. Levonorgestrel is used in bothoral combination birth control products and polymeric implantsthat provide contraception for up to 5 years.
Safety Profile
Human reproductive effects byingestion and implant: menstrual cycle changes ordisorders and female fertility index changes. Anexperimental teratogen. Experimental reproductiveeffects. Questionable carcinogen with experimentalneoplastigenic data. An o
References
[1] R C JONES R A E A C Singer. The biological activities of norgestrel and its enantiomers.[J]. International Journal of Fertility, 1979, 24 1: 39-43.
[2] M.S. R C J. The Effects of an Intrauterine Device Containing Norgestrel in the Rat[J]. Fertility and sterility, 1974, 25 9: Pages 767-771. DOI: 10.1016/s0015-0282(16)40631-x
Norgestrel Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 | sales@ichemie.com | China | 1006 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 615 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21586 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 | ada@ipurechemical.com | CHINA | 3461 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9996 | 58 |
View Lastest Price from Norgestrel manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-17 | Norgestrel
6533-00-2
|
50g | 98%-102%;USP | 10KG | WUHAN FORTUNA CHEMICAL CO., LTD | ||
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2026-06-16 | Norgestrel
6533-00-2
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
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2026-05-11 | Norgestrel
6533-00-2
|
$31.00-70.00 | 99.71% | 10g | TargetMol Chemicals Inc. |
-

- Norgestrel
6533-00-2
- 98%-102%;USP
- WUHAN FORTUNA CHEMICAL CO., LTD
-

- Norgestrel
6533-00-2
- 0.99
- RongNa Biotechnology Co.,Ltd
-

- Norgestrel
6533-00-2
- $31.00-70.00
- 99.71%
- TargetMol Chemicals Inc.






