1-Benzyl-2,5-dihydro-1H-pyrrole
- CAS No.
- 6913-92-4
- Chemical Name:
- 1-Benzyl-2,5-dihydro-1H-pyrrole
- Synonyms
- BPL;-3-pyrroL;N-Bn pyrrolin;N-BENZYLPYRROLINE;N-BENZYL-3-PYRROLINE;1-BENZYL-3-PYRROLINE;1-Benzyl-3-pyrrolidon;1-Benzyl-3-pyrroline 97%;1-Benzyl-3-pyrroline, 98+%;1-Benzyl-2,5-dihydropyrrole
- CBNumber:
- CB2778039
- Molecular Formula:
- C11H13N
- Molecular Weight:
- 159.23
- MDL Number:
- MFCD00012324
- MOL File:
- 6913-92-4.mol
- MSDS File:
- SDS
| Boiling point | 60 °C1 mm Hg(lit.) |
|---|---|
| Density | 0.837 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 198 °F |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| pka | 8.95±0.50(Predicted) |
| form | Liquid |
| color | Colorless to pale yellow |
| Sensitive | Air Sensitive |
| BRN | 111101 |
| InChIKey | LRFHKHHUKGZIGE-UHFFFAOYSA-N |
| CAS DataBase Reference | 6913-92-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314-H227-H318 | |||||||||
| Precautionary statements | P210e-P260h-P303+P361+P353-P405-P501a-P280-P305+P351+P338-P310 | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34 | |||||||||
| Safety Statements | 26-27-36/37/39-45-20 | |||||||||
| RIDADR | UN 3267 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29339900 | |||||||||
| Limited Quantities | 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
1-Benzyl-2,5-dihydro-1H-pyrrole price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B130493 | 1-Benzyl-3-pyrroline | 6913-92-4 | 100mg | $60 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB138888 | 1-Benzyl-3-pyrroline | 6913-92-4 | 1g | $70 | 2021-12-16 | Buy |
| Matrix Scientific | 113693 | 1-Benzyl-3-pyrroline 97% | 6913-92-4 | 1g | $79 | 2021-12-16 | Buy |
| Apolloscientific | OR480683 | 1-Benzyl-2,5-dihydropyrrole 96% | 6913-92-4 | 5g | $147 | 2021-12-16 | Buy |
| SynQuest Laboratories | 3H32-1-8R | 1-Benzyl-2,5-dihydropyrrole 96% | 6913-92-4 | 5G | $162 | 2021-12-16 | Buy |
1-Benzyl-2,5-dihydro-1H-pyrrole Chemical Properties,Uses,Production
Uses
1-Benzyl-3-pyrroline was used in synthesis of (S)-1-benzyl-3-hydroxypyrrolidine.
Synthesis
1476-11-5
100-46-9
6913-92-4
The general procedure for the synthesis of N-benzyl-3-pyrroline from cis-1,4-dichloro-2-butene and benzylamine was as follows: the synthesis was carried out according to the literature method with the following modifications: a) cis-1,4-dichloro-2-butene (0.76 g, 5.77 mmol) was dissolved in anhydrous dichloromethane (4 ml) at 5 °C; b) benzylamine was slowly added dropwise to the above solution ( 3.75 g, 34.66 mmol) to the above solution. The reaction mixture was stirred at 5°C for 10 min and then moved to room temperature and continued stirring for 24 hrs. After completion of the reaction, the resulting white solid was collected by filtration and washed with dichloromethane. The filtrate was cooled to 0°C, 37% hydrochloric acid (0.6 ml) was added, and the white solid was collected by filtration again and washed with dichloromethane. The filtrate was concentrated to give an orange oil, which was purified by fast chromatography (silica gel as stationary phase, hexane: ethyl acetate = 1:1 as eluent) to finally obtain N-benzyl-3-pyrroline (0.76 g, 82% yield) as a yellow oil. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3) and 13C NMR (75 MHz, CDCl3): 1H NMR δ 7.38-7.21 (m, 5H), 5.78 (s, 2H), 3.80 (s, 3H), 3.81 (s, 2H), 3.48 (s, 4H); 13C NMR δ 139.67, 128.69, 128.34, 127.78, 126.96, 60.40, 59.70.
References
[1] Patent: EP1849770, 2007, A1. Location in patent: Page/Page column 14
[2] Patent: EP1849781, 2007, A1. Location in patent: Page/Page column 88
[3] Patent: EP1849772, 2007, A1. Location in patent: Page/Page column 18
[4] Synthetic Communications, 1983, vol. 13, # 13, p. 1117 - 1124
[5] Synlett, 2002, # 1, p. 167 - 169
1-Benzyl-2,5-dihydro-1H-pyrrole Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29734 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Zjartschem | +86-571 87238903 | jocelynpan@zjarts.com | CHINA | 988 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29852 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14360 | 58 |
View Lastest Price from 1-Benzyl-2,5-dihydro-1H-pyrrole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-04-04 | 1-Benzyl-2,5-dihydro-1H-pyrrole
6913-92-4
|
US $0.00-0.00 / KG | 1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd.
|
|
 |
2019-07-06 | 1-Benzyl-2,5-dihydro-1H-pyrrole
6913-92-4
|
US $2.00 / KG | 1KG | 99% | customise | Career Henan Chemical Co |
-
- 1-Benzyl-2,5-dihydro-1H-pyrrole
6913-92-4
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 1-Benzyl-2,5-dihydro-1H-pyrrole
6913-92-4
- US $2.00 / KG
- 99%
- Career Henan Chemical Co
