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Afamelanotide acetate

Afamelanotide acetate Structure
Afamelanotide acetate structure
CAS No.
1566590-77-9
Chemical Name:
Afamelanotide acetate
Synonyms
Afamelanotide acetate;Afamelanotide acetate, 10 mM in DMSO;(Nle4,D-Phe7)-α-MSHAfaMelanotide, NDP-MSH, Melanotan 1, CUV1647
CBNumber:
CB28054870
Molecular Formula:
C80H115N21O21
Molecular Weight:
1706.93
MDL Number:
MOL File:
1566590-77-9.mol
Last updated:2025-05-13 16:19:24
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Afamelanotide acetate Properties

FDA UNII 1XCC161YKC

Afamelanotide acetate Chemical Properties,Uses,Production

Uses

Afamelanotide promotes skin pigmentation and provides protection from the sun. In dermatology, afamelanotide appears to be effective in treating polymorphic light eruption, solar urticaria, erythropoietic protoporphyria (EPP), Heili-Heili disease, vitiligo, and acne vulgaris. Afamelanotide may also be used non-medically to achieve quick and easy skin tanning[2].

General Description

Afamelanotide, a synthetic α-melanocyte stimulating hormone analog and first-in-class melanocortin-1 receptor agonist, has been approved in the EU for the prevention of phototoxicity in adults with erythropoietic protoporphyria (EPP)[1].

Side effects

Common adverse reactions to afamelanotide include headache and implant site reactions. Other adverse reactions include the development and aggravation of melanocytic nevi, degeneration of melanocytic nevi into melanoma, dark spots, systemic toxicity, rhabdomyolysis, posterior reversible encephalopathy syndrome, acromegaly, and oral soft tissue pigmentation. In addition, dentists should be alert to oral soft tissue pigmentation caused by afamelanotide[2].

IC 50

MC1R

References

[1] ESTHER S. KIM; Karly P G J. Afamelanotide: A Review in Erythropoietic Protoporphyria[J]. American Journal of Clinical Dermatology, 2016, 17 2: 179-185. DOI:10.1007/s40257-016-0184-6.
[2] C DE BAAT. [Medicaments and oral healthcare. Hyperpigmentation of oral soft tissues due to afamelanotide].[J]. Nederlands tijdschrift voor tandheelkunde, 2020, 127 4: 237-243. DOI:10.5177/ntvt.2020.04.19115.

Afamelanotide acetate Preparation Products And Raw materials

Raw materials

Preparation Products

Afamelanotide acetate Suppliers

Global( 23)Suppliers
Supplier Tel Email Country ProdList Advantage
Nantong Guangyuan Chemicl Co,Ltd 		+undefined17712220823 admin@guyunchem.com China 615 58
Hebei Kangcang new material Technology Co., LTD 		+8615713292910 Nancy@kangcang.com.cn China 341 58
Strong peptide cross-border e-commerce Co. LTD 		+undefined13930052870 qt01@qiangtaipharm.com China 84 58
American HealthyMorph LLC 		+8613363867578 nancyyuan133@163.com China 169 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32268 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38663 58
Jinan Million Pharmaceutical Co., Ltd 		0531-68659554 +8613031714605 info@millionpharm.com China 291 58
Cellmano Biotech Limited 0551-65326643 18156095617 info@cellmano.com China 1011 55
Shanghai Luofa Biochemical Technology Co., Ltd. 021-51111890 15317326293 sales@molnova.com China 4195 58
Supplier Advantage
Nantong Guangyuan Chemicl Co,Ltd 		58
Hebei Kangcang new material Technology Co., LTD 		58
Strong peptide cross-border e-commerce Co. LTD 		58
American HealthyMorph LLC 		58
TargetMol Chemicals Inc. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
TargetMol Chemicals Inc. 		58
Jinan Million Pharmaceutical Co., Ltd 		58
Cellmano Biotech Limited 55
Shanghai Luofa Biochemical Technology Co., Ltd. 58

View Lastest Price from Afamelanotide acetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Afamelanotide acetate pictures 2025-05-13 Afamelanotide acetate
1566590-77-9
 US $67.00-242.00 / mg 98% 10g TargetMol Chemicals Inc.
afamelanotide pictures 2025-04-29 afamelanotide
1566590-77-9
 US $40.00-35.00 / box 1box 99.9+ 2000box Strong peptide cross-border e-commerce Co. LTD
afamelanotide pictures 2025-04-29 afamelanotide
1566590-77-9
 US $40.00-35.00 / box 1box 99.9+ 2000box Strong peptide cross-border e-commerce Co. LTD
  • afamelanotide pictures
  • afamelanotide
    1566590-77-9
  • US $40.00-35.00 / box
  • 99.9+
  • Strong peptide cross-border e-commerce Co. LTD
  • afamelanotide pictures
  • afamelanotide
    1566590-77-9
  • US $40.00-35.00 / box
  • 99.9+
  • Strong peptide cross-border e-commerce Co. LTD

1566590-77-9(Afamelanotide acetate)Related Search:

H-MET-GLU-VAL-GLY-TRP-TYR-ARG-PRO-PRO-PHE-SER-ARG-VAL-VAL-HIS-LEU-TYR-ARG-ASN-GLY-LYS-OH XENOPSIN-RELATED PEPTIDE 1 ANGIOTENSINOGEN (1-14) (RAT) (TRP6)-LHRH GALANIN (2-29) (RAT)
(Nle4,D-Phe7)-α-MSHAfaMelanotide, NDP-MSH, Melanotan 1, CUV1647 Afamelanotide acetate Afamelanotide acetate, 10 mM in DMSO 1566590-77-9