Lacnotuzumab
- CAS No.
- 1831128-32-5
- Chemical Name:
- Lacnotuzumab
- Synonyms
- Lacnotuzumab;Lacnotuzumab (anti-M-CSF);Research Grade Lacnotuzumab
- CBNumber:
- CB28081030
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
| form | Liquid |
|---|---|
| color | Colorless to light yellow |
| FDA UNII | 77624NN1TU |
Lacnotuzumab price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0623894 | Lacnotuzumab 99.9% | 1831128-32-5 | 1mg | $433 | 2026-06-04 | Buy |
| ChemScene | CS-0623894 | Lacnotuzumab 99.9% | 1831128-32-5 | 5mg | $1517 | 2026-06-04 | Buy |
| ChemScene | CS-0623894 | Lacnotuzumab 99.9% | 1831128-32-5 | 10mg | $2437 | 2026-06-04 | Buy |
| aablocks | AA02EO82 | Lacnotuzumab ≥95%(SDS-PAGE&SEC-HPLC) | 1831128-32-5 | 1mg | $532 | 2026-06-03 | Buy |
| aablocks | AA02EO82 | Lacnotuzumab ≥95%(SDS-PAGE&SEC-HPLC) | 1831128-32-5 | 5mg | $2000 | 2026-06-03 | Buy |
Lacnotuzumab Chemical Properties,Uses,Production
Uses
Lacnotuzumab (MCS110) is a neutralizing humanized IgG1/κ monoclonal antibody targeting CSF-1 that prevents CSF-1 from activating the CSF-1R. Lacnotuzumab can be used for the research of pigmented villonodular synovitis[1][2].
in vivo
Lacnotuzumab neutralizes recombinant and serum-derived forms of cynomolgus CSF-1, but it does not recognize rodent or rabbit CSF-1[2].
References
[1] Kuemmel S, et, al. A Randomized Phase II Study of Anti-CSF1 Monoclonal Antibody Lacnotuzumab (MCS110) Combined with Gemcitabine and Carboplatin in Advanced Triple-Negative Breast Cancer. Clin Cancer Res. 2022 Jan 1;28(1):106-115. DOI:10.1158/1078-0432.CCR-20-3955
[2] Pognan F, et, al. Colony-Stimulating Factor-1 Antibody Lacnotuzumab in a Phase 1 Healthy Volunteer Study and Mechanistic Investigation of Safety Outcomes. J Pharmacol Exp Ther. 2019 Jun;369(3):428-442. DOI:10.1124/jpet.118.254128
Lacnotuzumab Preparation Products And Raw materials
Raw materials
Preparation Products
Lacnotuzumab Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Guangzhou Hongyuan Chemical Co.,Ltd | 15817493340 | 981810490@qq.com | China | 1577 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Biolab Reagents | 027-65279366 18108604356 | products@biolabreagent.com | China | 9864 | 58 |
| Wuhan Jingkangen Biomedical Technology Co., Ltd | 13720134139 086-15871494362 13720134139 | orders@jknbiochem.com | China | 7283 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Wuhan Acumen Bio-Technology Co.,ltd | 027-027-16602739303 16602739303 | 673003916@qq.com | China | 4593 | 58 |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | 6206333 13167063860 | anhua.mao@aladdin-e.com | China | 43379 | 58 |
