Ladiratuzumab
- CAS No.
- 1629760-28-6
- Chemical Name:
- Ladiratuzumab
- Synonyms
- hLIV22;Ladiratuzumab;Ladiratuzumab (anti-SLC39A6);Research Grade Ladiratuzumab;Research Grade Ladiratuzumab (DHG52901)
- CBNumber:
- CB28081050
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
| form | Liquid |
|---|---|
| color | Colorless to light yellow |
| FDA UNII | L0BJ40AQ0J |
Ladiratuzumab price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0628928 | Ladiratuzumab 99.76% | 1629760-28-6 | 1mg | $347 | 2026-06-04 | Buy |
| ChemScene | CS-0628928 | Ladiratuzumab 99.76% | 1629760-28-6 | 5mg | $704 | 2026-06-04 | Buy |
| ChemScene | CS-0628928 | Ladiratuzumab 99.76% | 1629760-28-6 | 10mg | $1137 | 2026-06-04 | Buy |
| ChemScene | CS-0628928 | Ladiratuzumab 99.76% | 1629760-28-6 | 25mg | $2275 | 2026-06-04 | Buy |
| aablocks | AA02A9AW | Ladiratuzumab ≥95%(SDS-PAGE&SEC-HPLC) | 1629760-28-6 | 1mg | $448 | 2026-06-02 | Buy |
Ladiratuzumab Chemical Properties, Uses, Production
Uses
Ladiratuzumab (hLIV22) is a humanized monoclonal antibody against zinc transporter LIV-1/ZIP6. Ladiratuzumab is conjugated to MMAE (HY-15162) via a cleavable dipeptide linker to synthesize an antibody-drug conjugate (ADC) Ladiratuzumab vedotin (HY-P99683). Ladiratuzumab vedotin selectively targets LIV-1 protein overexpressed on the surface of tumor cells, enters cells through antibody-mediated receptor endocytosis, releases MMAE to inhibit microtubule polymerization, and kills adjacent tumor cells with a bystander effect. Ladiratuzumab can be used in the study of solid tumors such as metastatic triple-negative breast cancer (mTNBC)[1][2].
References
[1] Trail PA, et al. Antibody drug conjugates for treatment of breast cancer: Novel targets and diverse approaches in ADC design. Pharmacol Ther. 2018 Jan;181:126-142. DOI:10.1016/j.pharmthera.2017.07.013
[2] Cao, et al. Additional mechanisms of action of ladiratuzumab vedotin contribute to increased immune cell activation within the tumor. Cancer Research 78.13_Supplement (2018): 2742-2742.
Ladiratuzumab Preparation Products And Raw materials
Raw materials
Preparation Products
Ladiratuzumab Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Biolab Reagents | 027-65279366 18108604356 | products@biolabreagent.com | China | 9864 | 58 |
| Wuhan Jingkangen Biomedical Technology Co., Ltd | 13720134139 086-15871494362 13720134139 | orders@jknbiochem.com | China | 7283 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Wuhan Acumen Bio-Technology Co.,ltd | 027-027-16602739303 16602739303 | 673003916@qq.com | China | 4593 | 58 |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | 6206333 13167063860 | anhua.mao@aladdin-e.com | China | 43439 | 58 |
View Latest Price from Ladiratuzumab manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-28 | Ladiratuzumab
1629760-28-6
|
$263.00-872.00 | 95.00% | 10g | TargetMol Chemicals Inc. |
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- Ladiratuzumab
1629760-28-6
- $263.00-872.00
- 95.00%
- TargetMol Chemicals Inc.
