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ChemicalBook >> CAS DataBase List >>Butanoic acid, 4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester

Butanoic acid, 4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester

Butanoic acid, 4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester Structure
Butanoic acid, 4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester structure
CAS No.
663598-89-8
Chemical Name:
Butanoic acid, 4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester
Synonyms
NO2-SPDB-sulfo;Butanoic acid, 4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester;1-((4-((5-nitropyridin-2-yl)disulfaneyl)butanoyl)oxy)-2,5-dioxopyrrolidine-3-sulfonic acid
CBNumber:
CB28202369
Molecular Formula:
C13H13N3O9S3
Molecular Weight:
451.45
MDL Number:
MFCD20227752
MOL File:
663598-89-8.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:56
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Butanoic acid, 4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester Properties

Density 1.76±0.1 g/cm3(Predicted)
pka -0.04±0.20(Predicted)

Butanoic acid, 4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA01FWJF 1-(4-((5-nitropyridin-2-yl)disulfanyl)butanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid >96% 663598-89-8 25mg $911 2026-05-30 Buy
aablocks AA01FWJF 1-(4-((5-nitropyridin-2-yl)disulfanyl)butanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid >96% 663598-89-8 100mg $2468 2026-05-30 Buy
aablocks AA01FWJF 1-(4-((5-nitropyridin-2-yl)disulfanyl)butanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid >96% 663598-89-8 250mg $4551 2026-05-30 Buy
aablocks AA01FWJF 1-(4-((5-nitropyridin-2-yl)disulfanyl)butanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid >96% 663598-89-8 500mg $6803 2026-05-30 Buy
Product number Packaging Price Buy
AA01FWJF 25mg $911 Buy
AA01FWJF 100mg $2468 Buy
AA01FWJF 250mg $4551 Buy
AA01FWJF 500mg $6803 Buy

Butanoic acid, 4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester Chemical Properties, Uses, Production

Uses

NO2-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC 50

Disulfide Cleavable Linker; Cleavable Linker

References

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268

Butanoic acid, 4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

Butanoic acid, 4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester Suppliers

Global Suppliers ( 6)
Supplier Tel Email Country ProdList Advantage
Affinity（Wuhan）Ltd. 15841022315 sales@affinitytech.cn China 2982 58
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 ET-market@chemextension.com China 38923 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 17634413542 1959525201@qq.com China 9011 58
Affinity Linkers Ltd. 15841022315 15841022315 sales@affinitytech.cn China 7039 58
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 sales@molcore.com China 49709 58
Supplier Advantage
Affinity（Wuhan）Ltd. 58
Jilin Chinese Academy of Sciences-yanshen Technology 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 58
Affinity Linkers Ltd. 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58

663598-89-8 (Butanoic acid, 4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester) Related Search:

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Butanoic acid, 4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester NO2-SPDB-sulfo 1-((4-((5-nitropyridin-2-yl)disulfaneyl)butanoyl)oxy)-2,5-dioxopyrrolidine-3-sulfonic acid 663598-89-8 C13H13N3O9S3