Wkymvm-NH2 TFA
- CAS No.
- 1435781-74-0
- Chemical Name:
- Wkymvm-NH2 TFA
- Synonyms
- Wkymvm-NH2 TFA
- CBNumber:
- CB29273049
- Molecular Formula:
- C43H62F3N9O9S2
- Molecular Weight:
- 970.14
- MDL Number:
- MFCD19443869
- MOL File:
- 1435781-74-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Wkymvm-NH2 TFA price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0129658 | WKYMVM-NH2 (TFA) 99.67% | 1435781-74-0 | 5mg | $260 | 2026-06-04 | Buy |
| ChemScene | CS-0129658 | WKYMVM-NH2 (TFA) 99.67% | 1435781-74-0 | 10mg | $412 | 2026-06-04 | Buy |
| aablocks | AA029IYW | WKYMVM-NH2 (TFA) >98% | 1435781-74-0 | 5mg | $302 | 2026-06-02 | Buy |
| aablocks | AA029IYW | WKYMVM-NH2 (TFA) >98% | 1435781-74-0 | 10mg | $458 | 2026-06-02 | Buy |
| Arctom | HY-P1121A | WKYMVM-NH2 TFA 99.67% | 1435781-74-0 | 5mg | $228 | 2026-05-26 | Buy |
Wkymvm-NH2 TFA Chemical Properties, Uses, Production
Uses
WKYMVM-NH2 TFA is a potent N-formyl peptide receptor (FPR1) and FPRL1/2 agonist, also activates several leukocyte effector functions such as chemotaxis, mobilization of complement receptor-3, and activation of the NADPH oxidase[1][2][3].
in vivo
WKYMVM-NH2 TFA (8mg/kg; six times; for 5 days) ameliorates DSS-induced ulcerative colitis[3].
WKYMVM-NH2 TFA affects cytokine (IL-17, IFN-γ, IL-6, IL-1β and TNF-α) profiles in the DSS colitis model[3].
| Animal Model: | Six-week-old C57BL/6 mice, DSS model[3] |
| Dosage: | 8mg/kg |
| Administration: | Subcutaneously injected, six subcutaneous administrations at 12-h intervals, for 5 days |
| Result: | Attenuated the DSS-induced increase in the bleeding score and the stool score. |
References
[1] Christophe T, et al. The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates neutrophils through FPRL1/lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2. J Biol Chem. 2001 Jun 15;276(24):21585-93. DOI:10.1074/jbc.M007769200
[2] Christophe T, et al. Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1/LXA4R, is not affected by lipoxin A4. Scand J Immunol. 2002 Nov;56(5):470-6. DOI:10.1046/j.1365-3083.2002.01149.x
[3] Sang Doo Kim, et al. The immune-stimulating peptide WKYMVm has therapeutic effects against ulcerative colitis. Exp Mol Med. 2013 Sep; 45(9): e40. DOI:10.1038/emm.2013.77
Wkymvm-NH2 TFA Preparation Products And Raw materials
Raw materials
Preparation Products
Wkymvm-NH2 TFA Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangzhou Younan Technology Co., Ltd | 020-82000279 18988941452 | YN_research@163.com | China | 2984 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9831 | 58 |
| Supplier | Advantage |
|---|---|
| Guangzhou Younan Technology Co., Ltd | 58 |
| RD International Technology Co., Limited | 58 |
