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3-Bromo-L-phenylalanine

3-Bromo-L-phenylalanine Structure
3-Bromo-L-phenylalanine structure
CAS No.
82311-69-1
Chemical Name:
3-Bromo-L-phenylalanine
Synonyms
L-3-Br-phe;L-3-BR-PHE-OH;3-Br-L-Phe-OH;L-Phe(3-Br)-OH;RRSYY(Avadomide)-5;(L)-Bromophenyl alanine;m-Bromo-L-phenylalanine;3-Bromo-L-phenylalanine;L-Phenylalanine, 3-bromo-;3-Bromo-L-phenylalanine,95%
CBNumber:
CB2948139
Molecular Formula:
C9H10BrNO2
Molecular Weight:
244.09
MDL Number:
MFCD06659110
MOL File:
82311-69-1.mol
MSDS File:
SDS
Last updated:2025-08-08 17:45:00
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3-Bromo-L-phenylalanine Properties

Boiling point 368.4±32.0 °C(Predicted)
Density 1.588±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 2.16±0.10(Predicted)
form solid
color White to off white
optical activity Consistent with structure
Water Solubility Slightly soluble in water.

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
HS Code  2922498590
NFPA 704
1
0 0

3-Bromo-L-phenylalanine price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 265342 3-Bromo- L-phenylalanine 82311-69-1 1g $379 2021-12-16 Buy
TRC B789320 3-Bromo-L-phenylalanine 82311-69-1 250mg $40 2021-12-16 Buy
TRC B789320 3-Bromo-L-phenylalanine 82311-69-1 1g $65 2021-12-16 Buy
Activate Scientific AS39494 (S)-2-Amino-3-(3-bromophenyl)propanoic acid 98% ee 82311-69-1 5G $67 2021-12-16 Buy
ChemScene CS-W008183 3-Bromo-L-phenylalanine 99.80% 82311-69-1 10g $70 2021-12-16 Buy
Product number Packaging Price Buy
265342 1g $379 Buy
B789320 250mg $40 Buy
B789320 1g $65 Buy
AS39494 5G $67 Buy
CS-W008183 10g $70 Buy

3-Bromo-L-phenylalanine Chemical Properties,Uses,Production

Uses

3-Bromo-L-phenylalanine is used in preparation of lifitegrast intermediate.

Chemical Properties

White to off-white powder

Uses

It is applied in the facile removal of leader peptides from lanthipeptides by incorporation of a hydroxy acid.

Uses

3-Bromo-L-phenylalanine is used in preparation of lifitegrast intermediate.

Synthesis

(S)-N-Boc-3-Bromophenylalanine

82278-73-7

3-Bromo-L-phenylalanine

82311-69-1

The general procedure for the synthesis of (S)-2-amino-3-(3-bromophenyl)propionic acid from (S)-3-(3-bromophenyl)-2-((tert-butoxycarbonyl)amino)propionic acid was as follows: (S)-3-(3-bromophenyl)-2-((tert-butoxycarbonyl)amino)propionic acid (5.0 g, 14.5 mmol) was suspended in a 1,4-dioxane solution of 4 M hydrochloric acid (75 mL ) and the reaction was stirred at room temperature for 16 hours. Upon completion of the reaction, the white precipitate was collected by filtration and washed with ether (Et2O) to afford (S)-2-amino-3-(3-bromophenyl)propionic acid (3.2 g, 89% yield) as a white solid, and the product did not require further purification. The nuclear magnetic resonance hydrogen spectrum (1H NMR, CDCl3) data of the product were as follows: δ 8.32 (2H, s), 7.50-7.48 (2H, m), 7.34-7.29 (2H, m), 4.22 (1H, t, J=6.2 Hz), 3.13-3.11 (2H, m).

References

[1] Patent: WO2008/47109, 2008, A1. Location in patent: Page/Page column 42
[2] Patent: WO2006/114606, 2006, A1. Location in patent: Page/Page column 61

3-Bromo-L-phenylalanine Preparation Products And Raw materials

Raw materials

(S)-N-Boc-3-Bromophenylalanine Hydrochloric acid 1,4-Dioxane

Preparation Products

L-Phenylalanine, N-[(5,7-dichloro-1,2,3,4-tetrahydro-6-isoquinolinyl)carbonyl]-3-(methylsulfonyl)-, phenylmethyl ester, hydrochloride (1:1) benzyl (S)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoate FMOC-L-4,4'-BIPHENYLALANINE (S)-N-Boc-3-Bromophenylalanine

3-Bromo-L-phenylalanine Suppliers

Global( 176)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+8613336195806 sales@capot.com China 29733 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21622 55
GenicBio Limited 		+86-21-37621270 service@genicbio.com CHINA 991 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29855 58
Zhejiang ZETian Fine Chemicals Co. LTD 		+8618957127338 stella@zetchem.com China 2136 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8497 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Chengdu Pukang Biotechnology Co., Ltd 		028-82550498 export@pu-kang.com CHINA 210 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
GenicBio Limited 		58
career henan chemical co 		58
Zhejiang ZETian Fine Chemicals Co. LTD 		58
Jinan Carbotang Biotech Co.,Ltd. 		58
Accela ChemBio Inc. 		58
Chengdu Pukang Biotechnology Co., Ltd 		58
Hubei xin bonus chemical co. LTD 		58
BOC Sciences 		58

View Lastest Price from 3-Bromo-L-phenylalanine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Bromo-L-phenylalanine pictures 2025-08-16 3-Bromo-L-phenylalanine
82311-69-1
 0.99 RongNa Biotechnology Co.,Ltd
3-Bromo-L-phenylalanine pictures 2025-04-04 3-Bromo-L-phenylalanine
82311-69-1
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
3-Bromo-L-phenylalanine pictures 2019-07-06 3-Bromo-L-phenylalanine
82311-69-1
 US $100.00 / KG 1KG 99% Customized Career Henan Chemical Co

3-Bromo-L-phenylalanine Spectrum

3-Bromo-L-phenylalanine(82311-69-1)1HNMR

82311-69-1(3-Bromo-L-phenylalanine)Related Search:

(2S)-2-amino-3-(3-carbamoylphenyl)propanoic acid L-3-Chlorophenylalanine FMOC-D-4-THIAZOLYLALANINE L-3-Cyanophenylalanine L-3-AMINOMETHYLPHE
4-Bromo-D-phenylalanine, N-BOC protected,N-alpha-t-Butyloxycarbonyl-4-bromo-D-phenylalanine,BOC-4-BROMO-D-PHENYLALANINE,BOC-P-BROMO-D-PHENYLALANINE FMOC-3-BROMO-L-PHENYLALANINE BOC-3-BROMO-L-PHENYLALANINE 2-BROMO-L-PHENYLALANINE BOC-(R)-4-BROMO-BETA-PHENYLALANINE
FMOC-(S)-4-BROMO-BETA-PHENYLALANINE BOC-(S)-4-BROMO-BETA-PHENYLALANINE FMOC-2-BROMO-L-PHENYLALANINE,N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-2-BROMO-L-PHENYLALANINE 3-BROMO-DL-PHENYLALANINE 4-BROMO-D-PHENYLALANINE
BOC-2-BROMO-L-PHENYLALANINE BOC-2-BROMO-D-PHENYLALANINE 4-BROMO-DL-PHENYLALANINE,4-Bromo-DL-phenylalanine, 98+%

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3-Bromo-L-phenylalanine (S)-2-Amino-3-(3'-Bromophenyl)Propanoic Acid (L)-Bromophenyl alanine 3-Br-L-Phe-OH (S)-2-((3-bromophenyl)amino)propanoic acid L-Phe(3-Br)-OH m-Bromo-L-phenylalanine L-3-BR-PHE-OH L-3-Br-phe L-Phenylalanine, 3-bromo- 3-Bromo-L-phenylalanine,95% 3-Bromo-L-phenylalanine USP/EP/BP RRSYY(Avadomide)-5 82311-69-1 Amino Acid Derivatives Amino Acids