ChemicalBook >> CAS DataBase List >>4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-[4-[2,6-difluoro-4-(2-methoxyethoxy)phenyl]-1-piperazinyl]-1,5-dihydro-1-methyl-

4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-[4-[2,6-difluoro-4-(2-methoxyethoxy)phenyl]-1-piperazinyl]-1,5-dihydro-1-methyl-

4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-[4-[2,6-difluoro-4-(2-methoxyethoxy)phenyl]-1-piperazinyl]-1,5-dihydro-1-methyl- structure

CAS No.: 1507370-78-6

Chemical Name:: 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-[4-[2,6-difluoro-4-(2-methoxyethoxy)phenyl]-1-piperazinyl]-1,5-dihydro-1-methyl-

Synonyms: G-631;4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-[4-[2,6-difluoro-4-(2-methoxyethoxy)phenyl]-1-piperazinyl]-1,5-dihydro-1-methyl-

CBNumber:: CB29784150

Molecular Formula:: C19H22F2N6O3

Molecular Weight:: 420.41

MDL Number:

MOL File:: 1507370-78-6.mol

MSDS File:: SDS

Last updated:2025-04-18 09:51:57

Request For Quotation

4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-[4-[2,6-difluoro-4-(2-methoxyethoxy)phenyl]-1-piperazinyl]-1,5-dihydro-1-methyl- Properties

Boiling point	580.1±60.0 °C(Predicted)
Density	1.47±0.1 g/cm3(Predicted)
pka	5.19±0.40(Predicted)

4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-[4-[2,6-difluoro-4-(2-methoxyethoxy)phenyl]-1-piperazinyl]-1,5-dihydro-1-methyl- price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-1184553	G-631 99.88%	1507370-78-6	5mg	$444	2026-06-04	Buy
ChemScene	CS-1184553	G-631 99.88%	1507370-78-6	10mg	$711	2026-06-04	Buy
ChemScene	CS-1184553	G-631 99.88%	1507370-78-6	25mg	$1421	2026-06-04	Buy
ChemScene	CS-1184553	G-631 99.88%	1507370-78-6	50mg	$2275	2026-06-04	Buy
ChemScene	CS-1184553	G-631 99.88%	1507370-78-6	100mg	$3412	2026-06-04	Buy

Product number	Packaging	Price	Buy
CS-1184553	5mg	$444	Buy
CS-1184553	10mg	$711	Buy
CS-1184553	25mg	$1421	Buy
CS-1184553	50mg	$2275	Buy
CS-1184553	100mg	$3412	Buy

4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-[4-[2,6-difluoro-4-(2-methoxyethoxy)phenyl]-1-piperazinyl]-1,5-dihydro-1-methyl- Chemical Properties, Uses, Production

Description

G-631 is a tankyrase inhibitior and a potential anticancer agent.

Uses

G-631 is a selective inhibitor for tankyrase. G-631 inhibits tankyrase auto-PARsylation (poly ADP ribosylation) with an IC50 of 7 nM, and inhibits Wnt signaling pathway. G-631 exhibits good pharmacokinetic characteristics in mice[1].

References

[1] Zhong Y, et al., Tankyrase Inhibition Causes Reversible Intestinal Toxicity in Mice with a Therapeutic Index < 1. Toxicol Pathol. 2016 Feb;44(2):267-78. DOI:10.1177/0192623315621192

4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-[4-[2,6-difluoro-4-(2-methoxyethoxy)phenyl]-1-piperazinyl]-1,5-dihydro-1-methyl- Preparation Products And Raw materials

Raw materials

Preparation Products

4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-[4-[2,6-difluoro-4-(2-methoxyethoxy)phenyl]-1-piperazinyl]-1,5-dihydro-1-methyl- Suppliers

Global Suppliers ( 3)

Supplier	Tel	Email	Country	ProdList	Advantage
Guangzhou Younan Technology Co., Ltd	020-82000279 18988941452	YN_research@163.com	China	2984	58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	025-025-66113011 15955137747	cb5@aikonchem.com	China	10354	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
Guangzhou Younan Technology Co., Ltd	58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	58
TargetMol Chemicals Inc.	58

1507370-78-6 (4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-[4-[2,6-difluoro-4-(2-methoxyethoxy)phenyl]-1-piperazinyl]-1,5-dihydro-1-methyl-) Related Search:

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4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-[4-[2,6-difluoro-4-(2-methoxyethoxy)phenyl]-1-piperazinyl]-1,5-dihydro-1-methyl- G-631 1507370-78-6