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ChemicalBook >> CAS DataBase List >>Cyclopropanecarboxamide, 1-(2-fluorophenyl)-N-[1-(2-fluoro-4-pyridinyl)-1H-pyrazol-3-yl]-

Cyclopropanecarboxamide, 1-(2-fluorophenyl)-N-[1-(2-fluoro-4-pyridinyl)-1H-pyrazol-3-yl]-

Cyclopropanecarboxamide, 1-(2-fluorophenyl)-N-[1-(2-fluoro-4-pyridinyl)-1H-pyrazol-3-yl]- Structure
Cyclopropanecarboxamide, 1-(2-fluorophenyl)-N-[1-(2-fluoro-4-pyridinyl)-1H-pyrazol-3-yl]- structure
CAS No.
2227482-41-7
Chemical Name:
Cyclopropanecarboxamide, 1-(2-fluorophenyl)-N-[1-(2-fluoro-4-pyridinyl)-1H-pyrazol-3-yl]-
Synonyms
ELOVL1-27;ELOVL1-IN-1;ELOVL1-IN-27;ELOVL1-IN-1, 10 mM in DMSO;1-(2-Fluorophenyl)-N-(1-(2-fluoropyridin-4-YL)-1H-pyrazol-3-YL)cyclopropane-1-carboxamide;Cyclopropanecarboxamide, 1-(2-fluorophenyl)-N-[1-(2-fluoro-4-pyridinyl)-1H-pyrazol-3-yl]-;chain,inhibit,adrenoleukodystrophy,Inhibitor,ELOVL1IN1,ALD,fatty,ELOVL-1-IN-1,acid,ELOVL1 IN 1,long
CBNumber:
CB310022981
Molecular Formula:
C18H14F2N4O
Molecular Weight:
340.33
MDL Number:
MOL File:
2227482-41-7.mol
MSDS File:
SDS
Last updated:2026-08-30 11:39:11
Request For Quotation

Cyclopropanecarboxamide, 1-(2-fluorophenyl)-N-[1-(2-fluoro-4-pyridinyl)-1H-pyrazol-3-yl]- Properties

Boiling point 584.1±50.0 °C(Predicted)
Density 1.40±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: insol; DMSO: 2 mg/ml; Ethanol: insol; PBS (pH 7.2): insol
form A crystalline solid
pka 12.79±0.20(Predicted)
color White to off-white

Cyclopropanecarboxamide, 1-(2-fluorophenyl)-N-[1-(2-fluoro-4-pyridinyl)-1H-pyrazol-3-yl]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 35323 ELOVL1-27 ≥98% 2227482-41-7 1mg $109 2026-04-30 Buy
Cayman Chemical 35323 ELOVL1-27 ≥98% 2227482-41-7 5mg $355 2026-04-30 Buy
Cayman Chemical 35323 ELOVL1-27 ≥98% 2227482-41-7 10mg $545 2026-04-30 Buy
Cayman Chemical 35323 ELOVL1-27 ≥98% 2227482-41-7 25mg $953 2026-04-30 Buy
ChemScene CS-0356501 ELOVL1-IN-1 98.02% 2227482-41-7 5mg $385 2026-06-04 Buy
Product number Packaging Price Buy
35323 1mg $109 Buy
35323 5mg $355 Buy
35323 10mg $545 Buy
35323 25mg $953 Buy
CS-0356501 5mg $385 Buy

Cyclopropanecarboxamide, 1-(2-fluorophenyl)-N-[1-(2-fluoro-4-pyridinyl)-1H-pyrazol-3-yl]- Chemical Properties, Uses, Production

Uses

ELOVL1-IN-1 is an ELOVL1 inhibitor extracted from patent WO2018107056A1, compound 87. ELOVL1-IN-1 can reduce very long chain fatty acid levels. ELOVL1-IN-1 can be used for the research of adrenoleukodystrophy (ALD)[1].

Biological Activity

ELOVL1-IN-1 is an ELOVL1 inhibitor extracted from patent WO2018107056A1, compound 87. ELOVL1-IN-1 can reduce very long chain fatty acid levels. ELOVL1-IN-1 can be used for the research of adrenoleukodystrophy (ALD)[1]. ELOVL1-IN-1 (compound 87) (1 nM-10 μM; 48 h) reduces the the level of VLCFA, lysophosphatidylcholine (LPC) in adrenoleukodystrophy (ALD) patient fibroblasts and healthy human fibroblasts, ALD patient B‐lymphocytes, and human microglia[1]. ELOVL1-IN-1 (compound 87) reduces of a VLCFA level, specifically C26:0 LPC level in blood of ABCD1 knockout (KO) mice (0.5-64 mg/kg; p.o. once daily for 28 days), wild‐type (WT) rats (30-300 mg/kg; p.o. once daily for 7 days), and cynomolgous monkeys (30 mg/kg; p.o. once daily for 7 days)[1].

in vivo

ELOVL1-IN-1 (compound 87) reduces of a VLCFA level, specifically C26:0 LPC level in blood of ABCD1 knockout (KO) mice (0.5-64 mg/kg; p.o. once daily for 28 days), wild‐type (WT) rats (30-300 mg/kg; p.o. once daily for 7 days), and cynomolgous monkeys (30 mg/kg; p.o. once daily for 7 days)[1].

References

[1]. Charifson PS, et, al. 1,3-substitued pyrazole compounds useful for reduction of very long chain fatty acic levels. WO2018107056A1.

Cyclopropanecarboxamide, 1-(2-fluorophenyl)-N-[1-(2-fluoro-4-pyridinyl)-1H-pyrazol-3-yl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Cyclopropanecarboxamide, 1-(2-fluorophenyl)-N-[1-(2-fluoro-4-pyridinyl)-1H-pyrazol-3-yl]- Suppliers

Global Suppliers ( 17)
Supplier Tel Email Country ProdList Advantage
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2994 55
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 15317229551 15151849396@163.com China 975 58
Hangzhou Taorui Biotechnology Co., Ltd QQ1259737804 15268198094 sales@torreybio.com China 4130 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9831 58
Shanghai Amole Biotechnology Co., Ltd. 13370042665 18916960931 2596183085@qq.com China 17234 58
TargetMol Chemicals Inc. +1-781-999-5354; support@targetmol.com United States 38999 58
Supplier Advantage
Shanghai Beckham Medical Technology Co., Ltd 55
TargetMol Chemicals Inc. 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 58
Hangzhou Taorui Biotechnology Co., Ltd 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
RD International Technology Co., Limited 58
Shanghai Amole Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58

View Latest Price from Cyclopropanecarboxamide, 1-(2-fluorophenyl)-N-[1-(2-fluoro-4-pyridinyl)-1H-pyrazol-3-yl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ELOVL1-IN-1 pictures 2026-08-30 ELOVL1-IN-1
2227482-41-7
 $118.00-448.00 98.79% 10g TargetMol Chemicals Inc.
  • ELOVL1-IN-1 pictures
  • ELOVL1-IN-1
    2227482-41-7
  • $118.00-448.00
  • 98.79%
  • TargetMol Chemicals Inc.

2227482-41-7 (Cyclopropanecarboxamide, 1-(2-fluorophenyl)-N-[1-(2-fluoro-4-pyridinyl)-1H-pyrazol-3-yl]-) Related Search:

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Cyclopropanecarboxamide, 1-(2-fluorophenyl)-N-[1-(2-fluoro-4-pyridinyl)-1H-pyrazol-3-yl]- ELOVL1-IN-27 1-(2-Fluorophenyl)-N-(1-(2-fluoropyridin-4-YL)-1H-pyrazol-3-YL)cyclopropane-1-carboxamide ELOVL1-IN-1 chain,inhibit,adrenoleukodystrophy,Inhibitor,ELOVL1IN1,ALD,fatty,ELOVL-1-IN-1,acid,ELOVL1 IN 1,long ELOVL1-27 ELOVL1-IN-1, 10 mM in DMSO 2227482-41-7