H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH
- CAS No.
- 131580-10-4
- Chemical Name:
- H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH
- Synonyms
- β-Amyloid 1-16;DAEFRHDSGYEVHHQK;BETA-AMYLOID (1-16);Bate-Amyloid (1-16);β-Amyloid (1-16), human;AMyloid b-Protein (1-16);Amyloid β-Protein (1-16);Amyloid ?2-Protein (1-16);AMYLOID BETA-PROTEIN (1-16);Beta-Amyloid (1-16) Peptide
- CBNumber:
- CB3110326
- Molecular Formula:
- C84H119N27O28
- Molecular Weight:
- 1955.01
- MDL Number:
- MFCD00214592
- MOL File:
- 131580-10-4.mol
Density | 1.57±0.1 g/cm3(Predicted) |
---|---|
storage temp. | -15°C |
solubility | Soluble in DMSO |
form | Solid |
color | White to off-white |
Water Solubility | Soluble in water or aqueous buffer |
Sequence | H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-OH |
H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH price More Price(17)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Usbiological | A2275-58B | β-Amyloid [1-16] | 131580-10-4 | 1mg | $531 | 2021-12-16 | Buy |
Biosynth Carbosynth | FA108823 | Amyloid beta-Protein (1-16) trifluoroacetate salt | 131580-10-4 | 10mg | $636 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | PEP0000658 | BETA-AMYLOID (1-16) 95.00% | 131580-10-4 | 1MG | $636.7 | 2021-12-16 | Buy |
Biorbyt Ltd | orb364307 | Beta-Amyloid (1-16) > 95% | 131580-10-4 | 5mg | $736.1 | 2021-12-16 | Buy |
Biorbyt Ltd | orb364308 | Beta-Amyloid (1-16) > 95% | 131580-10-4 | 5mg | $788.8 | 2021-12-16 | Buy |
H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH Chemical Properties,Uses,Production
Uses
Aβ(s) peptides, their peptide fragments and mutated fragments are used to study a wide range of metabolic and regulatory functions including activation of kinases, regulation of cholesterol transport, function as a transcription factor, and regulators of inflammation. Aβ(s) peptides and their peptide fragments are also used to study oxidative stress, metal binding and mechanisms of protein cross-linking in the context of diseases such as Alzheimer?s disease and neurodegeneration.
in vivo
β-amyloid (1-16) fragment is considered as valid models to examine the contribution of the key histidine residues (His , His in mouse and His , His , His in human fragments) to the Ab–Cu2+ interaction. Oxidation targets for β-Amyloid (1-16) are the histidine residues coordinated to the metal ions. Copper is bound to Aβ in senile plaque of Alzheimer’s disease with β-Amyloid (1-16) taking part in the coordination of the Cu2+ ions. Cu2+ and Zn2+ are linked with the neurotoxicity of -Amyloid and free radical damage[1]. β-amyloid (1-16) is the minimal amino acidic sequence display a Cu coordination mode which involves three Histidines (His6, His13 and His14). β-amyloid (1-16) is supposed to be involved in metal binding[2]. Human β-amyloid interacts with zinc ions through its metal-binding domain 1-16. The C-tails of the two polypeptide chains of the rat Aβ(1-16) dimer are oriented in opposite directions to each other, which hinders the assembly of rat Aβ dimers into oligomeric aggregates. Thus, the differences in the structure of zinc-binding sites of human and rat β-Amyloid (1-16), their ability to form regular cross-monomer bonds, and the orientation of their hydrophobic C-tails could be responsible for the resistance of rats to Alzheimer's disease[3].
H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH Preparation Products And Raw materials
Raw materials
Preparation Products
H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 10997 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10406 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
Cellmano Biotech Limited | 0551-65326643 18156095617 | info@cellmano.com | China | 995 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 20601 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
Hangzhou Go Top Peptide Biotech | 0571-88211921 | sales1@gotopbio.com | CHINA | 2609 | 58 |
Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39031 | 58 |
View Lastest Price from H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2025-06-03 | Bate-Amyloid (1-16)
131580-10-4
|
US $0.10-0.30 / kg | 1kg | >98% | 20 tons | Zibo Hangyu Biotechnology Development Co., Ltd | |
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2025-06-03 | [Gln11] -Bate- Amyloid (1 - 16)
131580-10-4
|
US $0.10-0.30 / kg | 1kg | >95% | 20 tons | Zibo Hangyu Biotechnology Development Co., Ltd |
-
- Bate-Amyloid (1-16)
131580-10-4
- US $0.10-0.30 / kg
- >98%
- Zibo Hangyu Biotechnology Development Co., Ltd
-
- [Gln11] -Bate- Amyloid (1 - 16)
131580-10-4
- US $0.10-0.30 / kg
- >95%
- Zibo Hangyu Biotechnology Development Co., Ltd
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