Fluorochloridone | 61213-25-0

Fluorochloridone Properties

Melting point	67.65°C
Boiling point	212.5 °C
Density	1.3924 (estimate)
Flash point	>100 °C
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	-3.59±0.60(Predicted)
color	Pale Brown to Light Brown
Henry's Law Constant	2.6×10² mol/(m³Pa) at 25℃, Duchowicz et al. (2020)
LogP	3.360
CAS DataBase Reference	61213-25-0(CAS DataBase Reference)
FDA UNII	AO023ZB1BP
NIST Chemistry Reference	2-Pyrrolidinone, 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]-(61213-25-0)
EPA Substance Registry System	Flurochloridone (61213-25-0)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08,GHS07,GHS09
Signal word	Danger
Hazard statements	H302-H317-H360FD-H410
Precautionary statements	P264-P270-P301+P312-P330-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P273-P391-P501
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-27-36/37/39
RTECS	UY5746500

Fluorochloridone price More Price(22)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0081481	Flurochloridone ≥96%	61213-25-0	5mg	$32	2026-06-04	Buy
ChemScene	CS-0081481	Flurochloridone ≥96%	61213-25-0	10mg	$49	2026-06-04	Buy
ChemScene	CS-0081481	Flurochloridone ≥96%	61213-25-0	25mg	$87	2026-06-04	Buy
ChemScene	CS-0081481	Flurochloridone ≥96%	61213-25-0	50mg	$135	2026-06-04	Buy
ChemScene	CS-0081481	Flurochloridone ≥96%	61213-25-0	100mg	$211	2026-06-04	Buy

Product number	Packaging	Price	Buy
CS-0081481	5mg	$32	Buy
CS-0081481	10mg	$49	Buy
CS-0081481	25mg	$87	Buy
CS-0081481	50mg	$135	Buy
CS-0081481	100mg	$211	Buy

Fluorochloridone Chemical Properties, Uses, Production

Description

Flurochloridone is a pre-emergence herbicide used to control a range of weeds in umbelliferous crops and other such as cereals and potatoes. It has a moderate aqueous solubility and is not considered volatile. Under certain conditions it can be persistent in soils but tends not to be in water-sediment systems. Data for human health suggests a low mammalian oral toxicity but there may be risks for reproduction/development and fluorochloridone is classified as a skin sensitiser. With the exception of algae where toxicity is high, toxicity is moderate for most species.

Chemical Properties

Brown solid. Easily soluble in acetone, chlorobenzene, ethanol, xylene and other organic solvents, with a solubility of 100-150g/L. Solubility in kerosene <5g/L. The solubility in water is 28mg/L. Partition coefficient (n-octanol/water) 2300 (20°C). The half-life is 7d at 60°C and pH 4, 18d at 60°C and pH 7, and the half-life in soil is 11-100d.

Uses

Flurochloridone (FLC) is a monophenyl pyrrolidinone selective herbicide that can be used in herbicidal composition to control weed in crop fields. It is commonly used to inhibit weeds that occur during the growth of crop plants, such as grains, sunflowers, and potatoes.

Definition

ChEBI: Flurochloridone is a member of pyrrolidines, a member of (trifluoromethyl)benzenes and an organochlorine compound. It has a role as a carotenoid biosynthesis inhibitor, an agrochemical and a herbicide.

Synthesis

The synthesis of Fluorochloridone is as follows:To a 1L three-neck flask, N-allyl-N-dichloroacetyl-m-trifluoromethylaniline (31.1 g, 0.1 mol) and 715 ml of 1,2-dichloroethane were added as a solvent, dissolved under stirring, and then added. Cuprous chloride (2.97g, 0.03mol) and 2,2-bipyridyl (4.68g, 0.03mol) were reacted at 80°C for 3 hours, cooled to room temperature, and the reaction solution was filtered through a short silica gel column to give dichloromethane. Elution and desolvation yielded 31.3 g of pyrotropone, a content of 97%, an anti-contrast ratio of ≥3:1, and a yield of 97.6%.

Metabolic pathway

From hydrolytic and photolytic studies of flurochloridone in buffer solution, no hydrolysis of flurochloridone occurs at pH 5, 7, or 9 at 25°C or at pH 5 at 40°C. Appreciable hydrolysis occurs at 40°C at pH 7 and 9 with half-lives of 190 and 140 days, respectively. Five hydrolytic degradation products and six photolytic degradation products are identified. The major photolytic degradation product which contains 39% of the radioactivity is 4-(chloromethyl)-3-hydroxy-1-[3- (trifluoromethyl)phenyl]-2-pyrrolidinone with a mixture of cis and trans isomers. The formation of this major degradation product suggests that the major photolytic pathway involves homolytic cleavage of the carbon chlorine bond at the 3-position of the pyrrolidinone ring and the free radical intermediate can react with water to give the major product or eliminate the hydrogen radical to form 4- (chloromethyl)-1,5-dihydro-1-[3- (trifluoromethyl)phenyl]pyrrol-2H-one.

Mode of action

Flurochloridone is the active substance of some pre-emergence herbicides. It has an inhibitory effect on the synthesis of carotenoids, which protect chlorophylls against oxidative stress.

Toxicity evaluation

The acute oral LD50 of male rats is 4000 mg/kg, the acute transdermal LD50 of rabbits is >5000 mg/kg, and the acute inhalation of rats is LC50 10.3 mg/L (4h). Slightly irritating to rabbit skin and eyes.

References

[1] Patent: CN107868029, 2018, A. Location in patent: Paragraph 0012-0018

Pesticide Type

Herbicide

Fluorochloridone Preparation Products And Raw materials

Raw materials

Dichloroacetyl chloride Dichloroacetamide Allyl bromide 3-Aminobenzotrifluoride Allyl chloride

N-Allyl-2,2-dichloro-N-[3-(trifluoromethyl)phenyl]acetamide 2,2'-Bipyridine Copper(I) chloride 1,2-Dichloroethane

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Preparation Products

Fluorochloridone Suppliers

Global Suppliers ( 194)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Beijing Ouhe Technology Co., Ltd	13552068683 13522913783	2355560935@qq.com	China	11777	60
Sichuan Kulinan Technology Co., Ltd	400-1166-196 18981987031	cdhxsj@163.com	China	11674	57
The future of Shanghai Industrial Co., Ltd.	021-61552785	sales@shshiji.com	China	9531	55
Shanghai Raise Chemical Technology Co.,Ltd	+86-021-50935922		China	7854	55
Guangzhou Isun Pharmaceutical Co., Ltd	020-39119399 18927568969	isunpharm@qq.com	China	4773	55
Nanjing Sunlida Biological Technology Co., Ltd.	025-57798810 18652991625	sales@sunlidabio.com	China	3223	55
TargetMol Chemicals Inc.	021-021-33632979 15002134094	marketing@targetmol.com	China	7993	58
Shanghai JONLN Reagent Co., Ltd.	400-0066400 13621662912	422131432@qq.com	China	9970	55
TianJin Alta Scientific Co., Ltd.	022-65378550-8551	contact@altascientific.com	China	2772	58

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Beijing Ouhe Technology Co., Ltd	60
Sichuan Kulinan Technology Co., Ltd	57
The future of Shanghai Industrial Co., Ltd.	55
Shanghai Raise Chemical Technology Co.,Ltd	55
Guangzhou Isun Pharmaceutical Co., Ltd	55
Nanjing Sunlida Biological Technology Co., Ltd.	55
TargetMol Chemicals Inc.	58
Shanghai JONLN Reagent Co., Ltd.	55
TianJin Alta Scientific Co., Ltd.	58

View Latest Price from Fluorochloridone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-02	Fluorochloridone 61213-25-0	$1.10-35.00	1kg	99%		Henan Fengda Chemical Co., Ltd
2026-07-17	Flurochloridone 61213-25-0	$35.00-98.00		99.86%	10g	TargetMol Chemicals Inc.
2026-03-20	Fluorochloridone 61213-25-0	$10.00	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd

Fluorochloridone
61213-25-0
$1.10-35.00
99%
Henan Fengda Chemical Co., Ltd

Flurochloridone
61213-25-0
$35.00-98.00
99.86%
TargetMol Chemicals Inc.

Fluorochloridone
61213-25-0
$10.00
99%
Hebei Chuanghai Biotechnology Co., Ltd

Fluorochloridone Spectrum

Fluorochloridone(61213-25-0)¹HNMR

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N-(Chloroacetyl)-3-(trifluoromethyl)aniline Methyl-2-pyrrolidone 1-Phenyl-2-pyrrolidinone

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r40244 (3RS,4RS,3RS,4RS)-3-chloro-4-chloromethyl-1-α,α,α-trifluoro-m-tolyl-2-pyrrolidone(3:1) 3-chloro-4-(chloromethyl)-1-(3-(trifluoromethyl)phenyl)-2-pyrrolidione FLUROCHLORIDON (MIXTURE OF ISOMERS),PEST （3RS， 4RS （3RS，4RS 3RS，4RS）-3-chloro-4-chloromethyl-1-(α,α,α-trifluoro-m-tolyl)-2-pyrrolidone(3:1) 1-[3-(Trifluoromethyl)phenyl]-3-chloro-4-(chloromethyl)pyrrolidin-2-one 3-Chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]-2-pyrrolizinone Racer 25 flurochloridone (bsi,draft e-iso,draft f-iso) raiser 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one FLUORCHLORIDONE FLUOROCHLORIDON FLUOROCHLORIDONE FLUROCHLORIDON RACER 1-(m-trifluoromethylphenyl)-3-chloro-4-chloromethyl-2-pyrrolidone 3-chloro-4-(chloromethyl)-1-(3-(trifluoromethyl)phenyl)-2-pyrrolidinon 3-chloro-4-(chloromethyl)-1-(3-(trifluoromethyl)phenyl)-2-pyrrolidinone 4-chloro-5-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]-2-pyrrolidinone Fluorine luo grass Flurochloridon@1000 μg/mL in Methanol Flurochloridon @100 μg/mL in Methanol Flurochloridone Solution luorochloridone Fluorochloridone 61213-25-0 4-CLTA Alfa-Trofodermin Clostene Flurochloridone 100 μg/ml Acetonitrile L13847500CY FlurochloridonE10μg/mLin Cyclohe XA13847500ALFlurochloridonE100μg/mLin Aceton Flurochloridone in Acetonitrile Flurochloridone 100 μg/mL in Acetonitrile FLUROCHLORIDONE 61213-25-0 C12H10Cl2F3NO Alpha sort E-GAlphabetic F FA - FLPesticides&Metabolites Herbicides Others Pesticides&Metabolites HERBICIDE