3-Pyridinecarbonitrile,6-formyl-(9CI)
- CAS No.
- 206201-64-1
- Chemical Name:
- 3-Pyridinecarbonitrile,6-formyl-(9CI)
- Synonyms
- 6-Formylcyanopyridine;5-Cyano-pyridin-2-carbaldehyde;6-formylpyridine-3-carbonitrile;6-Formyl-3-pyridinecarbonitrile;3-Pyridinecarbonitrile, 6-formyl-;3-Pyridinecarbonitrile,6-formyl-(9CI)
- CBNumber:
- CB31291765
- Molecular Formula:
- C7H4N2O
- Molecular Weight:
- 132.12
- MDL Number:
- MFCD13189079
- MOL File:
- 206201-64-1.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H312-H332-H335-H315-H319 |
| Precautionary statements | P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P280-P302+P352-P312-P322-P363-P501-P264-P280-P302+P352-P321-P332+P313-P362 |
| HS Code | 2933399990 |
3-Pyridinecarbonitrile,6-formyl-(9CI) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 276823 | 6-Formylnicotinonitrile Asreported | 206201-64-1 | 250mg | $814 | 2026-06-03 | Buy |
| Usbiological | 276823 | 6-Formylnicotinonitrile Asreported | 206201-64-1 | 500mg | $1168 | 2026-06-03 | Buy |
| Usbiological | 276823 | 6-Formylnicotinonitrile Asreported | 206201-64-1 | 1g | $1685 | 2026-06-03 | Buy |
| Usbiological | 276823 | 6-Formylnicotinonitrile Asreported | 206201-64-1 | 2g | $2555 | 2026-06-03 | Buy |
| Usbiological | 276823 | 6-Formylnicotinonitrile Asreported | 206201-64-1 | 5g | $3616 | 2026-06-03 | Buy |
3-Pyridinecarbonitrile,6-formyl-(9CI) Chemical Properties, Uses, Production
Synthesis
3222-48-8
206201-64-1
The general procedure for the synthesis of 6-formylnicotinonitrile from 5-cyano-2-methylpyridine is as follows: a mixed solution of 6-methylnicotinonitrile (10.0 g, 84.6 mmol) and iodine (20.0 g, 78.8 mmol) in dimethylsulfoxide (150 mL) was heated and reacted for 20 min at 150 °C under nitrogen protection (the off-gas generated during the reaction was required to be passed through a bleach washing to remove the dimethyl sulfide). After completion of the reaction, the reaction mixture was cooled to room temperature and slowly neutralized by adding saturated aqueous sodium bicarbonate solution (200 mL). Subsequently, the mixture was extracted with toluene (3 x 100 mL). The organic phases were combined, washed with saturated brine, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure to remove the solvent, yielding the orange oily target product 6-formylnicotinonitrile (5.65 g, 50% yield), which could be used in subsequent reactions without further purification. The structure of the product was confirmed by 1H NMR (CDCl3, 400 MHz): δ 8.06 (1H, d), 8.17 (1H, dd), 9.05 (1H, d), 10.12 (1H, s).
References
[1] Chemical Science, 2015, vol. 7, # 1, p. 346 - 357
[2] Patent: WO2007/96763, 2007, A2. Location in patent: Page/Page column 60
[3] Patent: US2002/19527, 2002, A1
[4] Patent: WO2013/6408, 2013, A1. Location in patent: Page/Page column 43
[5] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 1, p. 559 - 576
3-Pyridinecarbonitrile,6-formyl-(9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
3-Pyridinecarbonitrile,6-formyl-(9CI) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Synthfine Chemical Co.,Ltd | 15921303235 | sales@synthfine.com | China | 996 | 58 |
| Hebei Summedchem Co.,Ltd | 0319-5801333-8008 15630992918 | sales@summedchem.com | China | 1000 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Changsha Luxing Bio-Chem Technology Co., Ltd. | 0731-88827538 15574813303 | luxingbc@126.com | China | 1975 | 65 |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 8455 | 58 |
| NovoChemy Ltd. | 86-(0)21-31261262 373522135 | sales@novochemy.com | China | 6491 | 58 |
| Shanghai Chenzhu Pharmaceutical Co., Ltd. | 13162380607 | 1696175688@qq.com | China | 834 | 55 |
| Zhengzhou Alfachem Co., Ltd. | 0371-53765687 18937137882 | 3969243885@qq.com | China | 7734 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Changzhou Hopschain Chemical Co.,Ltd. | 85528066 13775048983 | sales@hopschem.com | China | 31548 | 55 |
View Latest Price from 3-Pyridinecarbonitrile,6-formyl-(9CI) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-11-20 | 3-Pyridinecarbonitrile,6-formyl-(9CI)
206201-64-1
|
1g | 95%min | 20kg/month | Nanjing jinheyou Trading Co., Ltd. |
-
- 3-Pyridinecarbonitrile,6-formyl-(9CI)
206201-64-1
- $0.00
- 95%min
- Nanjing jinheyou Trading Co., Ltd.
