ChemicalBook >> CAS DataBase List >>Benzamide, 2-[[2-[[4-(aminosulfonyl)phenyl]amino]-5-bromo-4-pyrimidinyl]amino]-6-fluoro-

Benzamide, 2-[[2-[[4-(aminosulfonyl)phenyl]amino]-5-bromo-4-pyrimidinyl]amino]-6-fluoro-

Benzamide, 2-[[2-[[4-(aminosulfonyl)phenyl]amino]-5-bromo-4-pyrimidinyl]amino]-6-fluoro- structure

CAS No.: 2488761-18-6

Chemical Name:: Benzamide, 2-[[2-[[4-(aminosulfonyl)phenyl]amino]-5-bromo-4-pyrimidinyl]amino]-6-fluoro-

Synonyms: TMX-3013;Benzamide, 2-[[2-[[4-(aminosulfonyl)phenyl]amino]-5-bromo-4-pyrimidinyl]amino]-6-fluoro-

CBNumber:: CB312923202

Molecular Formula:: C17H14BrFN6O3S

Molecular Weight:: 481.3

MDL Number:

MOL File:: 2488761-18-6.mol

Last updated:2025-04-18 09:52:03

Request For Quotation

Benzamide, 2-[[2-[[4-(aminosulfonyl)phenyl]amino]-5-bromo-4-pyrimidinyl]amino]-6-fluoro- Properties

Boiling point	679.4±65.0 °C(Predicted)
Density	1.743±0.06 g/cm3(Predicted)
pka	9.75±0.12(Predicted)

Benzamide, 2-[[2-[[4-(aminosulfonyl)phenyl]amino]-5-bromo-4-pyrimidinyl]amino]-6-fluoro- price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0566639	TMX-3013 98.02%	2488761-18-6	5mg	$227	2026-06-04	Buy
ChemScene	CS-0566639	TMX-3013 98.02%	2488761-18-6	10mg	$347	2026-06-04	Buy
ChemScene	CS-0566639	TMX-3013 98.02%	2488761-18-6	25mg	$558	2026-06-04	Buy
ChemScene	CS-0566639	TMX-3013 98.02%	2488761-18-6	50mg	$834	2026-06-04	Buy

Product number	Packaging	Price	Buy
CS-0566639	5mg	$227	Buy
CS-0566639	10mg	$347	Buy
CS-0566639	25mg	$558	Buy
CS-0566639	50mg	$834	Buy

Benzamide, 2-[[2-[[4-(aminosulfonyl)phenyl]amino]-5-bromo-4-pyrimidinyl]amino]-6-fluoro- Chemical Properties, Uses, Production

Uses

TMX-3013 is a CDKs inhibitor capable of inhibiting the activity of CDK1, CDK2, CDK4, CDK5, and CDK6, with IC50 values of 0.9 nM, <0.5 nM, 24.5 nM, 0.5 nM, and 15.6 nM, respectively. TMX-3013 can be utilized for synthesizing PROTACs that feature a polyethylene glycol (PEG) linker arm and Thalidomide (HY-14658) as the CRBN-recruiting arm[1].

IC 50

CDK1: 0.9 nM (IC₅₀); CDK2: <0.5 nM (IC₅₀); CDK4: 24.5 nM (IC₅₀); CDK5: 0.5 nM (IC₅₀); CDK6: 15.6 nM (IC₅₀)

References

[1] Teng M, et al. Development of CDK2 and CDK5 dual degrader TMX‐2172[J]. Angewandte Chemie, 2020, 132(33): 13969-13974. DOI:10.1002/anie.202004087

Benzamide, 2-[[2-[[4-(aminosulfonyl)phenyl]amino]-5-bromo-4-pyrimidinyl]amino]-6-fluoro- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzamide, 2-[[2-[[4-(aminosulfonyl)phenyl]amino]-5-bromo-4-pyrimidinyl]amino]-6-fluoro- Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol	400-821-0310 15002144251	xuexiang.shao@tsbiochem.com	China	29128	58

Supplier	Advantage
TargetMol	58

2488761-18-6 (Benzamide, 2-[[2-[[4-(aminosulfonyl)phenyl]amino]-5-bromo-4-pyrimidinyl]amino]-6-fluoro-) Related Search:

CDK12-CCNK HETERODIMER Protein, HUMAN (SF9) CDK3-CCNE1 HETERODIMER Protein, HUMAN (SF9) THZ1 GSK-3326595 Roscovitine

Anti-Aging Compound Library

1of2

Benzamide, 2-[[2-[[4-(aminosulfonyl)phenyl]amino]-5-bromo-4-pyrimidinyl]amino]-6-fluoro- TMX-3013 2488761-18-6 C17H14BrFN6O3S