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Ergoline-8-carboxamide, N-[3-[di(methyl-d3)amino]propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-, (8β)-

Ergoline-8-carboxamide, N-[3-[di(methyl-d3)amino]propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-, (8β)- structure

CAS No.: 2738376-76-4

Chemical Name:: Ergoline-8-carboxamide, N-[3-[di(methyl-d3)amino]propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-, (8β)-

Synonyms: Ergoline-8-carboxamide, N-[3-[di(methyl-d3)amino]propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-, (8β)-

CBNumber:: CB313237230

Molecular Formula:: C26H31D6N5O2

Molecular Weight:: 457.64

MDL Number:

MOL File:: 2738376-76-4.mol

MSDS File:: SDS

Last updated:2025-08-21 14:05:29

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Ergoline-8-carboxamide, N-[3-[di(methyl-d3)amino]propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-, (8β)- Properties

Density	1.157±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
solubility	Acetonitrile: Soluble DMSO: Soluble

Ergoline-8-carboxamide, N-[3-[di(methyl-d3)amino]propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-, (8β)- price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	31690	Cabergoline-d6 ≥99%deuteratedforms(d₁-d₆)	2738376-76-4	100μg	$189	2026-04-30	Buy
Cayman Chemical	31690	Cabergoline-d6 ≥99%deuteratedforms(d₁-d₆)	2738376-76-4	250μg	$442	2026-04-30	Buy
Cayman Chemical	31690	Cabergoline-d6 ≥99%deuteratedforms(d₁-d₆)	2738376-76-4	500μg	$836	2026-04-30	Buy
Cayman Chemical	31690	Cabergoline-d6 ≥99%deuteratedforms(d₁-d₆)	2738376-76-4	1mg	$1579	2026-04-30	Buy
ChemScene	CS-0377139	Cabergoline-d6	2738376-76-4	1mg	$2681	2026-06-04	Buy

Product number	Packaging	Price	Buy
31690	100μg	$189	Buy
31690	250μg	$442	Buy
31690	500μg	$836	Buy
31690	1mg	$1579	Buy
CS-0377139	1mg	$2681	Buy

Ergoline-8-carboxamide, N-[3-[di(methyl-d3)amino]propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-, (8β)- Chemical Properties, Uses, Production

Uses

Cabergoline-d6 is deuterium labeled Cabergoline. Cabergoline is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).

IC 50

D₃ Receptor; D₂ Receptor

References

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Odaka H, et al. Cabergoline, dopamine D2 receptor agonist, prevents neuronal cell death under oxidative stress via reducing excitotoxicity. PLoS One. 2014 Jun 10;9(6):e99271. DOI:10.1371/journal.pone.0099271
[3] Jefferson F, et al. A dopamine receptor d2-type agonist attenuates the ability of stress to alter sleep in mice. Endocrinology. 2014 Nov;155(11):4411-21. DOI:10.1210/en.2014-1134
[4] M MIYAGI. Dopamine receptor affinities in vitro and stereotypic activities in vivo of cabergoline in rats.[J]. Biological & pharmaceutical bulletin, 1996, 19 9: 1210-1213. DOI: 10.1248/bpb.19.1210
[5] K EGUCHI. Effect of cabergoline, a dopamine agonist, on estrogen-induced rat pituitary tumors: in vitro culture studies.[J]. Endocrine journal, 1995, 42 3: 413-420. DOI: 10.1507/endocrj.42.413
[6] SHAO JIAN LIN. Suppression of mTOR pathway and induction of autophagy-dependent cell death by cabergoline.[J]. Oncotarget, 2015, 6 36: 39329-39341. DOI: 10.18632/oncotarget.5744
[7] R. GRONDIN . Cabergoline, a long-acting dopamine D2-like receptor agonist, produces a sustained antiparkinsonian effect with transient dyskinesias in parkinsonian drug-naive primates[J]. Brain Research, 1996, 735 2: Pages 298-306. DOI: 10.1016/0006-8993(96)00597-5

Ergoline-8-carboxamide, N-[3-[di(methyl-d3)amino]propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-, (8β)- Preparation Products And Raw materials

Raw materials

Preparation Products

Ergoline-8-carboxamide, N-[3-[di(methyl-d3)amino]propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-, (8β)- Suppliers

Global Suppliers ( 4)

Supplier	Tel	Email	Country	ProdList	Advantage
Daicel Chiral Technologies (China)CO.,LTD	021-50460086-9 15921403865	han_yajun@dctc.daicel.com	China	7917	65
CHINA ISOTOPE CO., LIMITED	02151600108 13062666369	info@isotopechem.com	China	4721	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11963	58

Supplier	Advantage
Daicel Chiral Technologies (China)CO.,LTD	65
CHINA ISOTOPE CO., LIMITED	58
Shanghai Yifei Biotechnology Co. , Ltd.	58

2738376-76-4 (Ergoline-8-carboxamide, N-[3-[di(methyl-d3)amino]propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-, (8β)-) Related Search:

Coenzyme Q10-d6 Glycochenodeoxycholic acid-d4 Nilotinib-d6 PGPC-d6 Spermidine-d6

Ergoline-8-carboxamide, N-[3-[di(methyl-d3)amino]propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-, (8β)- 2738376-76-4