AOH1996
- CAS No.
- 2089314-64-5
- Chemical Name:
- AOH1996
- Synonyms
- AOH1196;N-[2-[[2-(3-methoxyphenoxy)phenyl]amino]-2-oxoethyl]-;N-(2-((2-(3-methoxyphenoxy)phenyl)amino)-2-oxoethyl)-1-naphthamide;N-[2-[2-(3-methoxyphenoxy)anilino]-2-oxoethyl]naphthalene-1-carboxamide;N-(2-((2-(3-Methoxyphenoxy)phenyl)amino)-2-oxoethyl)-1-naphthamide , AOH1996;AOH1996/N-[2-[2-(3-methoxyphenoxy)anilino]-2-oxoethyl]naphthalene-1-carboxamide;1-Naphthalenecarboxamide, N-[2-[[2-(3-methoxyphenoxy)phenyl]amino]-2-oxoethyl]-
- CBNumber:
- CB313247879
- Molecular Formula:
- C26H22N2O4
- Molecular Weight:
- 426.46
- MDL Number:
- MOL File:
- 2089314-64-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| AOH1996 ≥98% | 39526 | 1mg | $28 |
| AOH1996 ≥98% | 39526 | 5mg | $83 |
| AOH1996 ≥98% | 39526 | 25mg | $152 |
| N-(2-((2-(3-Methoxyphenoxy)phenyl)amino)-2-oxoethyl)-1-naphthamide | 305720 | 250.00mg | $150 |
| N-(2-((2-(3-Methoxyphenoxy)phenyl)amino)-2-oxoethyl)-1-naphthamide | 305720 | 1.00g | $391 |
| Boiling point | 703.9±50.0 °C(Predicted) |
|---|---|
| Density | 1.269±0.06 g/cm3(Predicted) |
| solubility |
Chloroform: Soluble Ethanol: Soluble Methanol: Soluble |
| pka | 12.87±0.70(Predicted) |
| InChI | InChI=1S/C26H22N2O4/c1-31-19-10-7-11-20(16-19)32-24-15-5-4-14-23(24)28-25(29)17-27-26(30)22-13-6-9-18-8-2-3-12-21(18)22/h2-16H,17H2,1H3,(H,27,30)(H,28,29) |
| InChIKey | HDMONPHKMIZXDH-UHFFFAOYSA-N |
| SMILES | C1(C(NCC(NC2=CC=CC=C2OC2=CC=CC(OC)=C2)=O)=O)=C2C(C=CC=C2)=CC=C1 |
AOH1996 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 39526 | AOH1996 ≥98% | 2089314-64-5 | 1mg | $28 | 2026-04-30 | Buy |
| Cayman Chemical | 39526 | AOH1996 ≥98% | 2089314-64-5 | 5mg | $83 | 2026-04-30 | Buy |
| Cayman Chemical | 39526 | AOH1996 ≥98% | 2089314-64-5 | 25mg | $152 | 2026-04-30 | Buy |
| Matrix Scientific | 305720 | N-(2-((2-(3-Methoxyphenoxy)phenyl)amino)-2-oxoethyl)-1-naphthamide | 2089314-64-5 | 250.00mg | $150 | 2026-05-19 | Buy |
| Matrix Scientific | 305720 | N-(2-((2-(3-Methoxyphenoxy)phenyl)amino)-2-oxoethyl)-1-naphthamide | 2089314-64-5 | 1.00g | $391 | 2026-05-19 | Buy |
AOH1996 Chemical Properties,Uses,Production
Description
AOH1996 is an inhibitor of proliferating cell nuclear antigen (PCNA).1 It binds to PCNA in a thermal shift assay. AOH1996 (500 nM) induces apoptosis in SK-N-DZ neuroblastoma cells but not 7SMOO32 normal neural crest stem cells. It induces DNA damage in SK-N-AS neuroblastoma cells expressing wild-type DNA-directed RNA polymerase II subunit RPB1 but not in SK-N-AS cells expressing RPB1Y418A. AOH1996 (40 mg/kg) decreases tumor volume in SK-N-BE(2)-C neuroblastoma, MDA-MB-468 breast cancer, and NCI H82 small cell lung cancer mouse xenograft models.WARNING This product is not for human or veterinary use.
References
[1] LONG GU . Small molecule targeting of transcription-replication conflict for selective chemotherapy[J]. Cell Chemical Biology, 2023, 30 10: Pages 1235-1247.e6. DOI: 10.1016/j.chembiol.2023.07.001
AOH1996 Preparation Products And Raw materials
Raw materials
Preparation Products
AOH1996 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Million Pharmaceutical Co., Ltd | 0531-68659554 +8613031714605 | info@millionpharm.com | China | 185 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32997 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shanghai UCHEM Inc. | +86-18930848214 +86-021-56762820 | sales@myuchem.com | China | 8898 | 58 |
| DEI MEI YI YAO KE JI LLC | +852-52854821 +852-52854821 | cici71684@gmail.com | China | 878 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +86-15965530500 | nickzhang@hangyubiotech.com | China | 9935 | 58 |
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +86-13119157289 | 18791163155@163.com | China | 3390 | 58 |
| Shanghai Guangyang Jiali Biotechnology Co., Ltd | 13407521611 | 46993711@qq.com | China | 176 | 58 |
| Hangzhou Collab Medicine Co.,Ltd. | +86-15936229464 | candice@collab-med.com | China | 999 | 58 |
