Cyclopropylboronic acid
- CAS No.
- 411235-57-9
- Chemical Name:
- Cyclopropylboronic acid
- Synonyms
- Cyclopropylboronic;Cyclopropaneboronic acid;AKOS BRN-0457;Boronocyclopropane;Cyclopropylboronica;CYCLOROPYLBORONIC ACID;CYCLOPROPYLBORONIC ACID;B-Cyclopropylboronic Acid;Boronic acid, cyclopropyl-;Cyclopropylboronic acid 95%
- CBNumber:
- CB3133570
- Molecular Formula:
- C3H7BO2
- Molecular Weight:
- 85.9
- MDL Number:
- MFCD04038750
- MOL File:
- 411235-57-9.mol
- MSDS File:
- SDS
| Melting point | 90-95 °C (lit.) |
|---|---|
| Boiling point | 205.1±23.0 °C(Predicted) |
| Density | 1.11±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO |
| pka | 10.49±0.20(Predicted) |
| form | Powder |
| color | white |
| Sensitive | moisture sensitive |
| InChI | InChI=1S/C3H7BO2/c5-4(6)3-1-2-3/h3,5-6H,1-2H2 |
| InChIKey | WLVKDFJTYKELLQ-UHFFFAOYSA-N |
| SMILES | C1CC1B(O)O |
| CAS DataBase Reference | 411235-57-9(CAS DataBase Reference) |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H319-H335-H302-H318-H360FD | |||||||||
| Precautionary statements | P201-P280-P305+P351+P338-P308+P313-P261-P280a-P304+P340-P405-P501a | |||||||||
| Hazard Codes | Xn,T | |||||||||
| Risk Statements | 22-36-61-60-36/37/38 | |||||||||
| Safety Statements | 26-36-45-53-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | No | |||||||||
| HazardClass | IRRITANT, IRRITANT-HARMFUL | |||||||||
| HS Code | 29319090 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Repr. 1B | |||||||||
| NFPA 704 |
|
Cyclopropylboronic acid price More Price(88)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 597988 | Cyclopropylboronic acid | 411235-57-9 | 1g | $110 | 2026-04-30 | Buy |
| Sigma-Aldrich | 597988 | Cyclopropylboronic acid | 411235-57-9 | 5g | $227 | 2026-04-30 | Buy |
| Strem Chemicals | 05-0440 | Cyclopropylboronic acid, min. 97% min.97% | 411235-57-9 | 1g | $79 | 2026-04-30 | Buy |
| Strem Chemicals | 05-0440 | Cyclopropylboronic acid, min. 97% min.97% | 411235-57-9 | 5g | $314 | 2026-04-30 | Buy |
| Biosynth | FC63289 | Cyclopropylboronic acid | 411235-57-9 | 0.1kg | $618.75 | 2026-06-04 | Buy |
Cyclopropylboronic acid Chemical Properties, Uses, Production
Chemical Properties
White to off-white powder
Uses
Cyclopropylboronic Acid is an organoboronic acid commonly used in highly efficient Suzuki coupling reactions.
Uses
Reagent used for• ;Microwave-assisted copper(II)-catalyzed N-cyclopropylation1• ;Nickel- and copper-catalyzed Suzuki-Miyaura coupling reaction of arenes2• ;Palladacycle-catalyzed Suzuki-cross coupling of aryl halides with cyclopropylboronic acid3• ;Palladium(0)-catalyzed cyclopropane C-H bond functionalization4• ;Palladium-catalyzed decarboxylative coupling5• ;Palladium-catalyzed ligand-directed oxidative functionalization of cyclopropanes6• ;Palladium-catalyzed Suzuki coupling reaction7Reagent used in Preparation of• ;Diaryl ketones by arylation
Uses
suzuki reaction
Synthesis
121-43-7
23719-80-4
411235-57-9
Cyclopropylmagnesium bromide (0.5 M in THF, 25 mL, 12.5 mmol) was added dropwise to a stirred solution of trimethylborate (1.69 g, 1.81 mL, 16.25 mmol) in tetrahydrofuran (7 mL) under nitrogen protection at -78°C. A white precipitate was observed during the reaction. A white precipitate was observed to form during the reaction. after 1 h, the reaction system was slowly warmed to room temperature and stirring was continued overnight. Upon completion of the reaction, the reaction was quenched with 2.0 N aqueous hydrochloric acid (20 mL) and the mixture was stirred for 1 hr. Subsequently, the reaction mixture was extracted with dichloromethane (15 mL) and the aqueous phase was back-extracted with deionized water (2 x 15 mL). All aqueous phases were combined and extracted with methyl tert-butyl ether (4 x 40 mL). The organic phases were combined, dried with anhydrous magnesium sulfate and concentrated under reduced pressure to give a white solid product. Two recrystallizations were carried out via a solvent mixture of dichloromethane and hexane, resulting in 252-297 mg of white solid product in 27% yield. The product was characterized by NMR hydrogen spectroscopy (250 MHz, CDCl3): δ 0.56-0.50 (2H, m, CH2), 0.42-0.40 (2H, m, CH2), -0.08 to -0.20 (1H, m, CH).
References
[1] Patent: WO2004/56788, 2004, A1. Location in patent: Page 51
Cyclopropylboronic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| AllyChem Co., Ltd. | 0411-62313318 13889470786 | info@allychem.com | China | 1021 | 65 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| Wuhan EnTai Technology Development Co,.Ltd | 86-27-82330560 | 2536851935@qq.com | China | 346 | 69 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Bridge Organics | +1269-649-4200 | ab@bridgeorganics.com | United States | 160 | 55 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
View Latest Price from Cyclopropylboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-14 | Cyclopropylboronic acid
411235-57-9
|
$19.00-166.00 | 5g | 0.98 | 25kg | Shanghai UCHEM Inc. | |
 |
2026-09-14 | Cyclopropylboronic acid
411235-57-9
|
$23.00 | 1kg | 99% | 20mt | Jinan Finer Chemical Co., Ltd | |
 |
2026-09-02 | Cyclopropylboronic acid
411235-57-9
|
$1.20-34.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd |
-
- Cyclopropylboronic acid
411235-57-9
- $19.00-166.00
- 0.98
- Shanghai UCHEM Inc.
-
- Cyclopropylboronic acid
411235-57-9
- $23.00
- 99%
- Jinan Finer Chemical Co., Ltd
-
- Cyclopropylboronic acid
411235-57-9
- $1.20-34.00
- 99%
- Henan Fengda Chemical Co., Ltd
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