Cyclopropylboronic acid
- CAS No.
- 411235-57-9
- Chemical Name:
- Cyclopropylboronic acid
- Synonyms
- Cyclopropylboronic;Cyclopropaneboronic acid;AKOS BRN-0457;Boronocyclopropane;Cyclopropylboronica;CYCLOROPYLBORONIC ACID;CYCLOPROPYLBORONIC ACID;B-Cyclopropylboronic Acid;Boronic acid, cyclopropyl-;Cyclopropylboronic acid 95%
- CBNumber:
- CB3133570
- Molecular Formula:
- C3H7BO2
- Molecular Weight:
- 85.9
- MDL Number:
- MFCD04038750
- MOL File:
- 411235-57-9.mol
- MSDS File:
- SDS
| Melting point | 90-95 °C (lit.) |
|---|---|
| Boiling point | 205.1±23.0 °C(Predicted) |
| Density | 1.11±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO |
| pka | 10.49±0.20(Predicted) |
| form | Powder |
| color | white |
| Sensitive | moisture sensitive |
| InChI | InChI=1S/C3H7BO2/c5-4(6)3-1-2-3/h3,5-6H,1-2H2 |
| InChIKey | WLVKDFJTYKELLQ-UHFFFAOYSA-N |
| SMILES | C1CC1B(O)O |
| CAS DataBase Reference | 411235-57-9(CAS DataBase Reference) |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H319-H335-H302-H318-H360FD | |||||||||
| Precautionary statements | P201-P280-P305+P351+P338-P308+P313-P261-P280a-P304+P340-P405-P501a | |||||||||
| Hazard Codes | Xn,T | |||||||||
| Risk Statements | 22-36-61-60-36/37/38 | |||||||||
| Safety Statements | 26-36-45-53-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | No | |||||||||
| HazardClass | IRRITANT, IRRITANT-HARMFUL | |||||||||
| HS Code | 29319090 | |||||||||
| NFPA 704 |
|
Cyclopropylboronic acid price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 597988 | Cyclopropylboronic acid | 411235-57-9 | 1g | $74.47 | 2025-07-31 | Buy |
| Sigma-Aldrich | 597988 | Cyclopropylboronic acid | 411235-57-9 | 5g | $169.76 | 2025-07-31 | Buy |
| Strem Chemicals | 05-0440 | Cyclopropylboronic acid, min. 97% | 411235-57-9 | 1g | $73 | 2024-03-01 | Buy |
| Strem Chemicals | 05-0440 | Cyclopropylboronic acid, min. 97% | 411235-57-9 | 5g | $294 | 2024-03-01 | Buy |
| Sigma-Aldrich | 597988 | Cyclopropylboronic acid | 411235-57-9 | 25g | $779 | 2025-07-31 | Buy |
Cyclopropylboronic acid Chemical Properties,Uses,Production
Chemical Properties
White to off-white powder
Uses
Cyclopropylboronic Acid is an organoboronic acid commonly used in highly efficient Suzuki coupling reactions.
Uses
Reagent used for• ;Microwave-assisted copper(II)-catalyzed N-cyclopropylation1• ;Nickel- and copper-catalyzed Suzuki-Miyaura coupling reaction of arenes2• ;Palladacycle-catalyzed Suzuki-cross coupling of aryl halides with cyclopropylboronic acid3• ;Palladium(0)-catalyzed cyclopropane C-H bond functionalization4• ;Palladium-catalyzed decarboxylative coupling5• ;Palladium-catalyzed ligand-directed oxidative functionalization of cyclopropanes6• ;Palladium-catalyzed Suzuki coupling reaction7Reagent used in Preparation of• ;Diaryl ketones by arylation
Uses
suzuki reaction
Synthesis
121-43-7
23719-80-4
411235-57-9
Cyclopropylmagnesium bromide (0.5 M in THF, 25 mL, 12.5 mmol) was added dropwise to a stirred solution of trimethylborate (1.69 g, 1.81 mL, 16.25 mmol) in tetrahydrofuran (7 mL) under nitrogen protection at -78°C. A white precipitate was observed during the reaction. A white precipitate was observed to form during the reaction. after 1 h, the reaction system was slowly warmed to room temperature and stirring was continued overnight. Upon completion of the reaction, the reaction was quenched with 2.0 N aqueous hydrochloric acid (20 mL) and the mixture was stirred for 1 hr. Subsequently, the reaction mixture was extracted with dichloromethane (15 mL) and the aqueous phase was back-extracted with deionized water (2 x 15 mL). All aqueous phases were combined and extracted with methyl tert-butyl ether (4 x 40 mL). The organic phases were combined, dried with anhydrous magnesium sulfate and concentrated under reduced pressure to give a white solid product. Two recrystallizations were carried out via a solvent mixture of dichloromethane and hexane, resulting in 252-297 mg of white solid product in 27% yield. The product was characterized by NMR hydrogen spectroscopy (250 MHz, CDCl3): δ 0.56-0.50 (2H, m, CH2), 0.42-0.40 (2H, m, CH2), -0.08 to -0.20 (1H, m, CH).
References
[1] Patent: WO2004/56788, 2004, A1. Location in patent: Page 51
Cyclopropylboronic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 8365 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20185 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 9029 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29734 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13357 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21620 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
View Lastest Price from Cyclopropylboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-10-10 | Cyclopropylboronic acid
411235-57-9
|
US $23.00 / kg | 1kg | 99% | 20mt | Jinan Finer Chemical Co., Ltd | |
 |
2025-10-08 | Cyclopropylboronic acid
411235-57-9
|
US $19.00-166.00 / g | 5g | 0.98 | 25kg | Shanghai UCHEM Inc. | |
 |
2025-09-25 | Cyclopropylboronic acid
411235-57-9
|
US $34.00-1.20 / kg | 1kg | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
-
- Cyclopropylboronic acid
411235-57-9
- US $23.00 / kg
- 99%
- Jinan Finer Chemical Co., Ltd
-
- Cyclopropylboronic acid
411235-57-9
- US $19.00-166.00 / g
- 0.98
- Shanghai UCHEM Inc.
-
- Cyclopropylboronic acid
411235-57-9
- US $34.00-1.20 / kg
- 99%
- Henan Fengda Chemical Co., Ltd
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