GK241
- CAS No.
- 1899930-93-8
- Chemical Name:
- GK241
- Synonyms
- GK241
- CBNumber:
- CB313503326
- Molecular Formula:
- C21H39NO4
- Molecular Weight:
- 369.55
- MDL Number:
- MOL File:
- 1899930-93-8.mol
- MSDS File:
- SDS
GK241 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 37689 | GK241 ≥98% | 1899930-93-8 | 1mg | $62 | 2026-04-30 | Buy |
| Cayman Chemical | 37689 | GK241 ≥98% | 1899930-93-8 | 5mg | $274 | 2026-04-30 | Buy |
| Cayman Chemical | 37689 | GK241 ≥98% | 1899930-93-8 | 10mg | $486 | 2026-04-30 | Buy |
| ChemScene | CS-1097763 | GK241 | 1899930-93-8 | 1mg | $219 | 2026-06-04 | Buy |
| ChemScene | CS-1097763 | GK241 | 1899930-93-8 | 5mg | $656 | 2026-06-04 | Buy |
GK241 Chemical Properties, Uses, Production
Uses
GK241 (compound 31a-c) is a 2-oxoamide-based compound that has inhibitory activity against human and mouse group IIA secretory phospholipase A2 (GIIA sPLA2) (IC50 of 143 nM and 68 nM, respectively), and its inhibitory mechanism was studied by molecular dynamics simulation.
References
[1] Development of a potent 2-oxoamide inhibitor of secreted phospholipase A2 guided by molecular docking calculations and molecular dynamics simulations
[2] MARIA A THEODOROPOULOU. Identification of a Dual Inhibitor of Secreted Phospholipase A2 (GIIA sPLA2) and SARS-CoV-2 Main Protease.[J]. Pharmaceuticals (Basel, Switzerland), 2022. DOI: 10.3390/ph15080961
[3] SOFIA VASILAKAKI . Inhibitors of secreted phospholipase A2 suppress the release of PGE2 in renal mesangial cells[J]. Bioorganic & Medicinal Chemistry, 2016, 24 13: Pages 3029-3034. DOI: 10.1016/j.bmc.2016.05.017
GK241 Preparation Products And Raw materials
Raw materials
Preparation Products
GK241 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
