CpG2007
- CAS No.
- 455348-63-7
- Chemical Name:
- CpG2007
- Synonyms
- CpG2007;5' TCG TCG TTG TCG TTT TGT CGT T 3'
- CBNumber:
- CB313503371
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
- MSDS File:
- SDS
CpG2007 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0542634 | ODN 2007 97.86% | 455348-63-7 | 1mg | $108 | 2026-06-04 | Buy |
| ChemScene | CS-0542634 | ODN 2007 97.86% | 455348-63-7 | 5mg | $184 | 2026-06-04 | Buy |
| ChemScene | CS-0542634 | ODN 2007 97.86% | 455348-63-7 | 10mg | $314 | 2026-06-04 | Buy |
CpG2007 Chemical Properties,Uses,Production
Uses
ODN 2007, a class B CpG ODN (oligodeoxynucleotide), is a Toll-like receptor (TLR) ligand. ODN 2007 can be used as an immunomodulator, vaccine adjuvant, and enhance immune responses in mammals, fish, and humans. ODN 2007 sequence: 5'-TCGTCGTTGTCGTTTTGTCGTT-3'[1][2][3].
in vivo
ODN 2007 (intraperitoneal injection, 1 μg, once) can enhance the immune response by regulating the expression of immune system-related genes in zebrafish infected withVibrio traumaticus FJ03-X2[2].
| Animal Model: | Zebrafish infected with Vibrio traumaticus FJ03-X2[2] |
| Dosage: | 1 μg |
| Administration: | Intraperitoneal injection; once |
| Result: | Showed a cumulative mortality rate of 15.0% in treated group while the control group reached 42.1%. Showed a significant decrease in the expression levels of all intestinal immune-related genes such as TNF、IFNg1-2、IL-1β、IL-10, especially IL-1β decreased by 99.88%. |
References
[1] Tamiru N Alkie, et al. Characterization of Innate Responses Induced by PLGA Encapsulated- and Soluble TLR Ligands In Vitro and In Vivo in Chickens. PLoS One. 2017 Jan 3;12(1):e0169154. DOI:10.1371/journal.pone.0169154
[2] Hua Chen, et al. CpG-ODN 2007 protects zebrafish (Danio rerio) against Vibrio vulnificus infection. Aquac Res. 2021; 52: 897-905.
[3] Audesh Bhat, et al. Role of Hsp90 in CpG ODN mediated immunostimulation in avian macrophages. Mol Immunol. 2010 Mar;47(6):1337-46. DOI:10.1016/j.molimm.2009.12.011
CpG2007 Preparation Products And Raw materials
Raw materials
Preparation Products
CpG2007 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Apextide Co Ltd | 15300650552; 15300650552 | info@apextide.com | China | 90 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8491 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| Nantong Hi-Future Biotechnology Co., Ltd | +86-0513; 18051384581 | sales@chemhifuture.com | China | 3074 | 58 |
| Asymchem Labs. | 17347534561 | liujiaqi11751@asymchem.com.cn | China | 433 | 58 |
| Xi'an Lechun Chemical Co., Ltd | 029-15596886083 15596886083 | 739383595@qq.com | China | 4142 | 58 |
| Nantong Hanfang Biotechnology Co. , Ltd. | hanfangpharma@126.com 18017580634 | hanfangpharma@126.com | China | 25800 | 58 |
| Shanghai meikai technology co., ltd | 021-68689288 15300790979 | info@mkbio.com.cn | China | 9988 | 58 |
| Shaanxi Didu Pharmaceutical Co., Ltd. | 029-81124775 17791530730 | 1079@dideu.com | China | 10000 | 58 |
| TargetMol | 400-821-0310 15002144251 | xuexiang.shao@tsbiochem.com | China | 29128 | 58 |
