C12-113
- CAS No.
- 1220890-27-6
- Chemical Name:
- C12-113
- Synonyms
- C12-113
- CBNumber:
- CB313731475
- Molecular Formula:
- C53H111N3O4
- Molecular Weight:
- 854.47
- MDL Number:
- MOL File:
- 1220890-27-6.mol
C12-113 Chemical Properties,Uses,Production
Uses
C12-113 is a lipidoid delivery agent that can be used to transfect siRNA into cells. C12-113 can also be combined with other lipids to form lipid nanoparticles (LNPs) for the delivery of mRNA encoding the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in mice[1][2].
References
[1] Li J, Song J S, et al. YY1 regulates melanocyte development and function by cooperating with MITF[J]. PLoS genetics, 2012, 8(5): e1002688. DOI:10.1371/journal.pgen.1002688
[2] XUEXIANG HAN. Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines[J]. Nature nanotechnology, 2023, 18 9: 1105-1114. DOI: 10.1038/s41565-023-01404-4
C12-113 Preparation Products And Raw materials
Raw materials
Preparation Products
C12-113 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Easy CDMO Co.,Ltd | 021-61734564 13854185395; | info@easycdmo.com | China | 10030 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | ET-market@chemextension.com | China | 31138 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29545 | 58 |
| Cayman Chemical Company | 800-364-9897 | sales@caymanchem.com | China | 6838 | 58 |
| Beijing Xiecheng Biotechnology Co., Ltd. | 18301438069 | CHINA | 153 | 58 |
