ChemicalBook >> CAS DataBase List >>8-[(2S,5R)-4-[Bis(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]-5-methyl-6-oxo-5,6-dihydro-1,5-naphthyridine-2-carbonitrile

8-[(2S,5R)-4-[Bis(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]-5-methyl-6-oxo-5,6-dihydro-1,5-naphthyridine-2-carbonitrile

8-[(2S,5R)-4-[Bis(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]-5-methyl-6-oxo-5,6-dihydro-1,5-naphthyridine-2-carbonitrile structure

CAS No.: 2407892-15-1

Chemical Name:: 8-[(2S,5R)-4-[Bis(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]-5-methyl-6-oxo-5,6-dihydro-1,5-naphthyridine-2-carbonitrile

Synonyms: BMS-332;8-[(2S,5R)-4-[Bis(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]-5-methyl-6-oxo-5,6-dihydro-1,5-naphthyridine-2-carbonitrile;1,5-Naphthyridine-2-carbonitrile, 8-[(2S,5R)-4-[bis(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]-5,6-dihydro-5-methyl-6-oxo-

CBNumber:: CB314213110

Molecular Formula:: C29H27F2N5O

Molecular Weight:: 499.56

MDL Number:

MOL File:: 2407892-15-1.mol

MSDS File:: SDS

Last updated:2025-05-19 13:47:26

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8-[(2S,5R)-4-[Bis(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]-5-methyl-6-oxo-5,6-dihydro-1,5-naphthyridine-2-carbonitrile Properties

Boiling point	616.192±55.00 °C(Press: 760.00 Torr)(predicted)
Density	1.342±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	5.778±0.70(predicted)
form	Solid
color	White to light yellow

8-[(2S,5R)-4-[Bis(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]-5-methyl-6-oxo-5,6-dihydro-1,5-naphthyridine-2-carbonitrile price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0901482	BMS-332 99.05%	2407892-15-1	5mg	$380	2026-06-04	Buy
ChemScene	CS-0901482	BMS-332 99.05%	2407892-15-1	10mg	$609	2026-06-04	Buy
ChemScene	CS-0901482	BMS-332 99.05%	2407892-15-1	25mg	$1219	2026-06-04	Buy
ChemScene	CS-0901482	BMS-332 99.05%	2407892-15-1	50mg	$1950	2026-06-04	Buy
aablocks	AA02DHQY	BMS-332 >98%	2407892-15-1	5mg	$425	2026-06-03	Buy

Product number	Packaging	Price	Buy
CS-0901482	5mg	$380	Buy
CS-0901482	10mg	$609	Buy
CS-0901482	25mg	$1219	Buy
CS-0901482	50mg	$1950	Buy
AA02DHQY	5mg	$425	Buy

8-[(2S,5R)-4-[Bis(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]-5-methyl-6-oxo-5,6-dihydro-1,5-naphthyridine-2-carbonitrile Chemical Properties,Uses,Production

Uses

BMS-332 is adualDGKα/ζlipid kinase inhibitor, with theIC50of 0.005 (DGKα) and 0.001 μM (DGKζ)[1].

References

[1] Wichroski M, et al. DGKα/ζ inhibitors combine with PD-1 checkpoint therapy to promote T cell-mediated antitumor immunity. Sci Transl Med. 2023;15(719):eadh1892. DOI:10.1126/scitranslmed.adh1892

8-[(2S,5R)-4-[Bis(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]-5-methyl-6-oxo-5,6-dihydro-1,5-naphthyridine-2-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

8-[(2S,5R)-4-[Bis(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]-5-methyl-6-oxo-5,6-dihydro-1,5-naphthyridine-2-carbonitrile Suppliers

Global( 2)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Beckham Medical Technology Co., Ltd	13816613772	huahero21@sina.com	China	2996	55
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
Shanghai Beckham Medical Technology Co., Ltd	55
TargetMol Chemicals Inc.	58

2407892-15-1(8-[(2S,5R)-4-[Bis(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]-5-methyl-6-oxo-5,6-dihydro-1,5-naphthyridine-2-carbonitrile)Related Search:

COCHLIOQUINONE A Anti-cancer compound library 1,5-Naphthyridine-2-carbonitrile, 5,6-dihydro-3-(2-hydroxyethoxy)-5-methyl-8-[4-(5-methyl-2-benzoxazolyl)-1-piperidinyl]-6-oxo- 1H-[1,2,4]Triazolo[3,4-b]purine-1-ethanamine, 4-[(2S,5R)-4-[bis(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]-N,N-dimethyl- 1,5-Naphthyridine-2-carbonitrile, 8-[(2S,5R)-4-[bis(4-chlorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]-5,6-dihydro-5-methyl-6-oxo-

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8-[(2S,5R)-4-[Bis(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]-5-methyl-6-oxo-5,6-dihydro-1,5-naphthyridine-2-carbonitrile BMS-332 1,5-Naphthyridine-2-carbonitrile, 8-[(2S,5R)-4-[bis(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]-5,6-dihydro-5-methyl-6-oxo- 2407892-15-1