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2-Bromo-1-(3-fluorophenyl)ethan-1-one

2-Bromo-1-(3-fluorophenyl)ethan-1-one structure

CAS No.: 53631-18-8

Chemical Name:: 2-Bromo-1-(3-fluorophenyl)ethan-1-one

Synonyms: ethan-1-one;BUTTPARK 35\01-52;3-FLUOROPHENACYL BROMIDE;3-Fluorophenacylbromide95%;2-Bromo-1-(3-fluorophenyl);3-Fluorophenacyl bromide 95%;3-Fluorophenacyl bromide ,97%;2-Bromo-3'-fluoroacetophenone;ALPHA-BROMO-3-FLUOROACETOPHENONE;2-Bromo-3'-fluoroacetophenone 97%

CBNumber:: CB3147915

Molecular Formula:: C8H6BrFO

Molecular Weight:: 217.04

MDL Number:: MFCD00109756

MOL File:: 53631-18-8.mol

MSDS File:: SDS

Last updated:2026-05-28 01:01:36

Product description	Number	Pack Size	Price
2-Bromo-3′-fluoroacetophenone 97%	669482	1g	$50.3
2-Bromo-3′-fluoroacetophenone 97%	669482	5g	$140
2-Bromo-1-(3-fluorophenyl)ethanone min. 95.0 %	B6512	1G	$45
2-Bromo-1-(3-fluorophenyl)ethanone min. 95.0 %	B6512	5G	$136
2-Bromo-3'-fluoroacetophenone Asreported	264521	2g	$398
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2-Bromo-1-(3-fluorophenyl)ethan-1-one Properties

Melting point	34-35
Boiling point	76°C 0,09mm
Density	1.568±0.06 g/cm3(Predicted)
Flash point	110 °C
storage temp.	2-8°C
form	solid
color	Faint to light yellow
Sensitive	Lachrymatory
InChI	InChI=1S/C8H6BrFO/c9-5-8(11)6-2-1-3-7(10)4-6/h1-4H,5H2
InChIKey	ITAQNNGDCNFGID-UHFFFAOYSA-N
SMILES	C(=O)(C1=CC=CC(F)=C1)CBr
CAS DataBase Reference	53631-18-8(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs	Respiratory system
PPE	dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes	C,Xi
Risk Statements	36/37/38-34
Safety Statements	26-36/37/39-45-27
RIDADR	UN 3335
WGK Germany	3
Hazard Note	Corrosive/Lachrymatory/Keep Cold
HazardClass	LACHRYMATOR, CORROSIVE
HS Code	29147000
Storage Class	11 - Combustible Solids
Hazard Classifications	Eye Irrit. 2 Skin Irrit. 2 STOT SE 3
Excepted Quantities	Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

2-Bromo-1-(3-fluorophenyl)ethan-1-one price More Price(75)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	669482	2-Bromo-3′-fluoroacetophenone 97%	53631-18-8	1g	$50.3	2026-04-30	Buy
Sigma-Aldrich	669482	2-Bromo-3′-fluoroacetophenone 97%	53631-18-8	5g	$140	2023-06-20	Buy
TCI Chemical	B6512	2-Bromo-1-(3-fluorophenyl)ethanone min. 95.0 %	53631-18-8	1G	$45	2026-04-30	Buy
TCI Chemical	B6512	2-Bromo-1-(3-fluorophenyl)ethanone min. 95.0 %	53631-18-8	5G	$136	2026-04-30	Buy
Usbiological	264521	2-Bromo-3'-fluoroacetophenone Asreported	53631-18-8	2g	$398	2026-06-03	Buy

Product number	Packaging	Price	Buy
669482	1g	$50.3	Buy
669482	5g	$140	Buy
B6512	1G	$45	Buy
B6512	5G	$136	Buy
264521	2g	$398	Buy

2-Bromo-1-(3-fluorophenyl)ethan-1-one Chemical Properties,Uses,Production

Chemical Properties

White solid

Synthesis

455-36-7

53631-18-8

GENERAL METHODS: Oxone (1.352 g, 2.2 mmol) was added to a well-stirred methanol (10 mL) solution of m-fluoroacetophenone (2 mmol) and NH4Br (0.215 g, 2.2 mmol) and the reaction mixture was stirred at room temperature (or reflux temperature). The progress of the reaction was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was quenched with aqueous sodium thiosulfate and extracted with ethyl acetate (3 × 25 mL). The organic layers were combined, washed with water, dried over anhydrous sodium sulfate, filtered, and concentrated in vacuum to remove the solvent to give the crude product. The crude product was further purified by silica gel column chromatography (200-300 mesh) to give pure 2-bromo-3'-fluoroacetophenone. All products were structurally confirmed by 1H NMR and mass spectrometry data.

References

[1] Tetrahedron Letters, 2012, vol. 53, # 2, p. 191 - 195
[2] Journal of Medicinal Chemistry, 2014, vol. 57, # 15, p. 6572 - 6582
[3] Patent: WO2008/46598, 2008, A1. Location in patent: Page/Page column 92
[4] RSC Advances, 2014, vol. 4, # 107, p. 62308 - 62320
[5] Journal of Organic Chemistry, 2013, vol. 78, # 14, p. 7312 - 7317

2-Bromo-1-(3-fluorophenyl)ethan-1-one synthesis

Synthesis of 2-Bromo-1-(3-fluorophenyl)ethan-1-one from Benzene, 1-(2-bromoethynyl)-3-fluoro-

2-Bromo-1-(3-fluorophenyl)ethan-1-one Preparation Products And Raw materials

Raw materials

3'-Fluoroacetophenone Chloroform Sodium bicarbonate Bromine Acetic acid

Methanol Ammonium bromide Potassium peroxymonosulfate

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Preparation Products

Ethanone, 1-(3-fluorophenyl)-2-(methylthio)- 2-BROMO-4-(3-FLUORO-PHENYL)-THIAZOLE

2-Bromo-1-(3-fluorophenyl)ethan-1-one Suppliers

Global( 164)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Changzhou Fullone Chemical Co., Ltd.	+86-13328197671 +86-13861172460	sales@borenchem.cn	China	1055	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20122	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	52513593@qq.com	CHINA	2972	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-0519-85551759 +8613506123987	marketing1@neostarunited.com	China	8828	58

Supplier	Advantage
Changzhou Fullone Chemical Co., Ltd.	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Changzhou Ansciep Chemical Co., Ltd.	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Fuxin Pharmaceutical	58
Neostar United (Changzhou) Industrial Co., Ltd.	58

View Lastest Price from 2-Bromo-1-(3-fluorophenyl)ethan-1-one manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-09-25	2-Bromo-1-(3-fluorophenyl)ethanone 53631-18-8	$1.00-200.00	1KG	99%, 99.5% Sublimated		Henan Fengda Chemical Co., Ltd
	2020-01-08	2-Bromo-1-(3-fluorophenyl)ethan-1-one 53631-18-8	$2.00	1KG	98%	100g , 1kg, 5kg , 50kg	Career Henan Chemical Co

2-Bromo-1-(3-fluorophenyl)ethanone
53631-18-8
$1.00-200.00
99%, 99.5% Sublimated
Henan Fengda Chemical Co., Ltd

2-Bromo-1-(3-fluorophenyl)ethan-1-one
53631-18-8
$2.00
98%
Career Henan Chemical Co

2-Bromo-1-(3-fluorophenyl)ethan-1-one Spectrum

2-Bromo-1-(3-fluorophenyl)ethan-1-one(53631-18-8)¹HNMR

53631-18-8(2-Bromo-1-(3-fluorophenyl)ethan-1-one)Related Search:

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Trifluoroacetophenone 3-Nitroacetophenone Allyl bromide

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BUTTPARK 35\01-52 3-FLUOROPHENACYL BROMIDE ALPHA-BROMO-3-FLUOROACETOPHENONE 2-BROMO-1-(3-FLUOROPHENYL)ETHAN-1-ONE Ethanone, 2-bromo-1-(3-fluorophenyl)- (9CI) 3-Fluorophenacyl bromide 95% 3-Fluorophenacylbromide95% 2-bromo-1-(3-fluorophenyl)ethanone 3-Fluorophenacyl bromide ,97% 2-Bromo-1-(3-fluorophenyl)propan-1-one 2-Bromo-3'-fluoroacetophenone ,97% 2-Bromo-3'-fluoroacetophenone, 2-Bromo-1-(3-fluorophenyl)ethan-1-one 2-Bromo-3'-fluoroacetophenone 97% 2-Bromo-1-(3-fluorophenyl) Ethanone, 2-bromo-1-(3-fluorophenyl)- 2-Bromo-3'-fluoroacetophenone 2-Bromo-3′-fluoroacetophenone, CAS 53631-18-8 ethan-1-one 53631-18-8 C7 to C8 Carbonyl Compounds Building Blocks Ketones Organic Building Blocks Fluorine series Acetophenone series ACETYLHALIDE