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2-amino-4-bromo-5-methylphenol

CAS No.
848358-81-6
Chemical Name:
2-amino-4-bromo-5-methylphenol
Synonyms
2-amino-4-bromo-5-methylphenol;Phenol,2-aMino-4-broMo-5-Methyl-;2-amino-4-bromo-5-methylphenol ISO 9001:2015 REACH
CBNumber:
CB31482141
Molecular Formula:
C7H8BrNO
Molecular Weight:
202.05
MDL Number:
MFCD11110463
MOL File:
848358-81-6.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:53

2-amino-4-bromo-5-methylphenol Properties

Boiling point 288.3±40.0 °C(Predicted)
Density 1.647±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 9.31±0.23(Predicted)
Appearance White to light yellow Solid
InChI InChI=1S/C7H8BrNO/c1-4-2-7(10)6(9)3-5(4)8/h2-3,10H,9H2,1H3
InChIKey OVFOSMHDFYXTCQ-UHFFFAOYSA-N
SMILES C1(O)=CC(C)=C(Br)C=C1N

SAFETY

Risk and Safety Statements

HS Code  2922290090

2-amino-4-bromo-5-methylphenol price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR400223 2-Amino-4-bromo-5-methylphenol 97% 848358-81-6 100mg $51 2026-06-04 Buy
Apolloscientific OR400223 2-Amino-4-bromo-5-methylphenol 97% 848358-81-6 250mg $62 2026-06-04 Buy
Apolloscientific OR400223 2-Amino-4-bromo-5-methylphenol 97% 848358-81-6 1g $166 2026-06-04 Buy
Apolloscientific OR400223 2-Amino-4-bromo-5-methylphenol 97% 848358-81-6 5g $588 2026-06-04 Buy
Activate Scientific AS45946 2-Amino-4-bromo-5-methylphenol 97% 848358-81-6 1g $224 2026-06-04 Buy
Product number Packaging Price Buy
OR400223 100mg $51 Buy
OR400223 250mg $62 Buy
OR400223 1g $166 Buy
OR400223 5g $588 Buy
AS45946 1g $224 Buy

2-amino-4-bromo-5-methylphenol Chemical Properties, Uses, Production

Synthesis

4-bromo-5-methyl-2-nitrophenol

182500-28-3

2-amino-4-bromo-5-methylphenol

848358-81-6

General procedure for the synthesis of 4-bromo-5-methyl-2-nitrophenol from 4-bromo-5-methyl-2-nitrophenol: To a stirred solution of 4-bromo-5-methyl-2-nitrophenol (1.8 g, 7.76 mmol) in methanol (20 mL) was added sequentially stannous chloride (II) dihydrate (5.88 g, 31.0 mmol) and concentrated hydrochloric acid (1.65 mL , 54.3 mmol) and the reaction was carried out at room temperature. The reaction mixture was heated to 75 °C and maintained for 2 hours. After completion of the reaction, the mixture was cooled to room temperature and concentrated under reduced pressure to remove the solvent. The crude product was dissolved with ethyl acetate (100 mL), the pH was adjusted to 14 with ammonia and the solid suspension formed was filtered through a bed of diatomaceous earth. The filtrate was washed with ethyl acetate (2 x 50 mL). The combined organic phases were washed sequentially with water (50 mL) and saturated saline (50 mL), dried over anhydrous sodium sulfate and filtered. The filtrate was concentrated under reduced pressure to afford 1.3 g (83% yield) of the target product 4-bromo-5-methyl-2-aminophenol as a white solid. The product was characterized by 1HNMR (400 MHz, CDCl3) and GC-MS: 1HNMR δ 6.96 (s, 1H), 6.64 (s, 1H), 3.61 (bs, 2H, D2O exchangeable), 2.26 (s, 3H); GC-MS (m/z) 201,203 [M+, Br79,81].

References

[1] Patent: US2016/145268, 2016, A1. Location in patent: Paragraph 0239
[2] Journal of the American Chemical Society, 1914, vol. 36, p. 1509
[3] Journal fuer Praktische Chemie (Leipzig), 1915, vol. <2>92, p. 125

2-amino-4-bromo-5-methylphenol Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 54)
Supplier Tel Email Country ProdList Advantage
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. 21-57721279 18121011378 sales@shydchem.com.cn China 998 56
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chiba Pharmaceutical Science and technology Co, Ltd. 0531-81313138 13066006660 chibapharm@foxmail.com China 3996 55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
ShangHai KenEn Chemical Technology Co., Ltd. 13120367189;18621755571 mychess007@163.com China 1994 55
Shanghai XR Chemical Technology Co., Ltd. 021-31007982 18019432809; info@xrpharma.com China 694 55
Suzhou Chenke Biotech Co., Ltd. 18662408853 2120408911@qq.com China 980 55
SuZhou ShiYa Biopharmaceuticals, Inc. 0512-0512-52358471 17715136450 sales@shiyabiopharm.com China 9814 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Henan Aosman Biotechnology Co., LTD 13761588971 17719817155 2366079749@qq.com China 3009 58

View Latest Price from 2-amino-4-bromo-5-methylphenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-amino-4-bromo-5-methylphenol pictures 2020-01-13 2-amino-4-bromo-5-methylphenol
848358-81-6
$9.80 1g ≥99% 100kg Career Henan Chemical Co

2-amino-4-bromo-5-methylphenol Spectrum

2-amino-4-bromo-5-methylphenol Phenol,2-aMino-4-broMo-5-Methyl- 2-amino-4-bromo-5-methylphenol ISO 9001:2015 REACH 848358-81-6 848786-95-6