1,5-Dibromo-2,4-difluorobenzene
- CAS No.
- 28342-75-8
- Chemical Name:
- 1,5-Dibromo-2,4-difluorobenzene
- Synonyms
- 1.3-Dibrom-4.6-difluorben;1.3-Dibrom-4.6-difluorbenzol;2,4-Difluoro-1,5-dibromobenzene;1,3-DibroMo-4,6-difluorobenzene;1,5-Dibromo-2,4-difluorobenzene;Benzene, 1,5-dibromo-2,4-difluoro-;1,5-Dibromo-2,4-difluorobenzene，98%;1,5-Dibromo-2,4-difluorobenzene 98%
- CBNumber:
- CB31496940
- Molecular Formula:
- C6H2Br2F2
- Molecular Weight:
- 271.88
- MDL Number:
- MFCD08458122
- MOL File:
- 28342-75-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 29.0 to 33.0 °C |
|---|---|
| Boiling point | 100℃ (25 Torr) |
| Density | 2.087±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| form | powder to lump |
| color | White to Almost white |
| InChI | InChI=1S/C6H2Br2F2/c7-3-1-4(8)6(10)2-5(3)9/h1-2H |
| InChIKey | PPUZKAPOPPRMFE-UHFFFAOYSA-N |
| SMILES | C1(Br)=CC(Br)=C(F)C=C1F |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P271-P280 | |||||||||
| HS Code | 2903998090 | |||||||||
| NFPA 704 |
|
1,5-Dibromo-2,4-difluorobenzene price More Price(50)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D5259 | 1,5-Dibromo-2,4-difluorobenzene >98.0%(GC) | 28342-75-8 | 1g | $28 | 2026-04-30 | Buy |
| Apolloscientific | PC9091 | 1,5-Dibromo-2,4-difluorobenzene 98% | 28342-75-8 | 5g | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC9091 | 1,5-Dibromo-2,4-difluorobenzene 98% | 28342-75-8 | 25g | $49 | 2026-06-04 | Buy |
| Apolloscientific | PC9091 | 1,5-Dibromo-2,4-difluorobenzene 98% | 28342-75-8 | 100g | $158 | 2026-06-04 | Buy |
| Activate Scientific | AS48946 | 1,5-Dibromo-2,4-difluorobenzene 98% | 28342-75-8 | 5g | $20 | 2026-06-04 | Buy |
1,5-Dibromo-2,4-difluorobenzene Chemical Properties, Uses, Production
Synthesis
348-57-2
28342-75-8
General procedure for the synthesis of 1,5-dibromo-2,4-difluorobenzene from 2,4-difluorobromobenzene: Iron powder (3.15 g, 56 mmol) was added to a solution of 1-bromo-2,4-difluorobenzene (19.3 mL, 171 mmol) in dichloromethane (100 mL). A dichloromethane (25 mL) solution of bromine (11 mL, 214 mmol) was slowly added dropwise to the stirred suspension over 30 minutes. The reaction mixture was stirred overnight at room temperature. Subsequently, the reaction mixture was slowly poured into saturated aqueous sodium thiosulfate solution (200 mL) and stirring was continued for 30 minutes at room temperature. The reaction mixture was extracted with dichloromethane (3 x 80 mL). The organic phases were combined, washed with brine, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give 1,5-dibromo-2,4-difluorobenzene (40 g, 86% yield) as a brown oil.1H NMR (500 MHz, chloroform-d) δ 7.79 (t, J = 7.0 Hz, 1H), 7.00 (t, J = 8.2 Hz, 1H).
References
[1] Journal of Organic Chemistry, 2004, vol. 69, # 6, p. 1967 - 1971
[2] Patent: WO2012/162334, 2012, A1. Location in patent: Page/Page column 38
[3] Patent: WO2014/98831, 2014, A1. Location in patent: Page/Page column 26; 27
[4] Nucleosides, Nucleotides and Nucleic Acids, 2001, vol. 20, # 1-2, p. 11 - 40
[5] Patent: EP1961743, 2008, A1. Location in patent: Page/Page column 19
1,5-Dibromo-2,4-difluorobenzene Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhengzhou TRIZ Pharmaceutical Technology Co., Ltd. | 19943855286 | 94644163@qq.com | China | 1934 | 56 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9336 | 55 |
| Shanghai potentpharm CO.,Ltd | (86) 21 51969655 | China | 486 | 22 |
View Latest Price from 1,5-Dibromo-2,4-difluorobenzene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 1,5-DIBROMO-2,4-DIFLUOROBENZENE
28342-75-8
|
$1.00-50.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-07-20 | 1,5-DIBROMO-2,4-DIFLUOROBENZENE
28342-75-8
|
1KG | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2019-07-14 | 1,5-DIBROMO-2,4-DIFLUOROBENZENE
28342-75-8
|
$1.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- 1,5-DIBROMO-2,4-DIFLUOROBENZENE
28342-75-8
- $1.00-50.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 1,5-DIBROMO-2,4-DIFLUOROBENZENE
28342-75-8
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 1,5-DIBROMO-2,4-DIFLUOROBENZENE
28342-75-8
- $1.00
- 99%
- Career Henan Chemical Co
