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2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL

CAS No.
349-67-7
Chemical Name:
2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL
Synonyms
2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL;Phenol, 2-methoxy-5-(trifluoromethyl)-
CBNumber:
CB31499815
Molecular Formula:
C8H7F3O2
Molecular Weight:
192.14
MDL Number:
MFCD09832299
MOL File:
349-67-7.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:46
Product description Number Pack Size Price
2-Methoxy-5-(trifluoromethyl)phenol M332240 50mg $45
2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL 95.00% HCH0357944 250MG $376.95
2-methoxy-5-(trifluoromethyl)phenol 98% CM183650 1g $464
2-Methoxy-5-(trifluoromethyl)phenol 349677 250mg $489.6
2-Methoxy-5-(trifluoromethyl)phenol 98% CD12080373 1g $491
More product size

2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL Properties

Boiling point 104-105 °C(Press: 12 Torr)
Density 1.321±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 8.97±0.10(Predicted)
Appearance Colorless to light yellow Liquid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H315-H318-H335
Precautionary statements  P261-P280-P305+P351+P338
HS Code  2907199090

2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M332240 2-Methoxy-5-(trifluoromethyl)phenol 349-67-7 50mg $45 2021-12-16 Buy
American Custom Chemicals Corporation HCH0357944 2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL 95.00% 349-67-7 250MG $376.95 2021-12-16 Buy
Chemenu CM183650 2-methoxy-5-(trifluoromethyl)phenol 98% 349-67-7 1g $464 2021-12-16 Buy
Alichem 349677 2-Methoxy-5-(trifluoromethyl)phenol 349-67-7 250mg $489.6 2021-12-16 Buy
Crysdot CD12080373 2-Methoxy-5-(trifluoromethyl)phenol 98% 349-67-7 1g $491 2021-12-16 Buy
Product number Packaging Price Buy
M332240 50mg $45 Buy
HCH0357944 250MG $376.95 Buy
CM183650 1g $464 Buy
349677 250mg $489.6 Buy
CD12080373 1g $491 Buy

2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL Chemical Properties,Uses,Production

Synthesis

2-METHOXY-5-TRIFLUOROMETHYLPHENYLBORONIC ACID

240139-82-6

2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL

349-67-7

The general procedure for the synthesis of 2-methoxy-5-trifluoromethylphenol from 2-methoxy-5-trifluoromethylphenylboronic acid was as follows: to a 100 mL round bottom flask was added [2-methoxy-5-(trifluoromethyl)phenyl]boronic acid (300 mg, 1.36 mmol, 1.00 eq.), ethanol (15 mL), and 30% hydrogen peroxide aqueous solution (2 mL). The reaction mixture was stirred at 80°C for 2 hours. Upon completion of the reaction, the mixture was concentrated under reduced pressure. Subsequently, water was added to dilute the reaction mixture. The mixture was washed with aqueous sodium sulfite and the aqueous layer was extracted with ethyl acetate and the organic layers were combined. The organic layer was washed with saturated brine, dried over anhydrous sodium sulfate and finally concentrated under reduced pressure to give 250 mg (95% yield) of 2-methoxy-5-(trifluoromethyl)phenol as a colorless oil.

References

[1] Patent: WO2015/130957, 2015, A1. Location in patent: Page/Page column 85
[2] Journal of Medicinal Chemistry, 2004, vol. 47, # 12, p. 3089 - 3104

240139-82-6
349-67-7
Synthesis of 2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL from 2-METHOXY-5-TRIFLUOROMETHYLPHENYLBORONIC ACID

2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL Preparation Products And Raw materials

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349-67-7(2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL)Related Search:

2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL Phenol, 2-methoxy-5-(trifluoromethyl)- 349-67-7