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H-Trp-Tyr-Lys-His-Val-Ala-Ser-Pro-Arg-Tyr-His-Thr-Val-Gly-Arg-Ala-Ala-Gly-Leu-Leu-Met-Gly-Leu-OH

H-Trp-Tyr-Lys-His-Val-Ala-Ser-Pro-Arg-Tyr-His-Thr-Val-Gly-Arg-Ala-Ala-Gly-Leu-Leu-Met-Gly-Leu-OH structure

CAS No.: 383415-79-0

Chemical Name:: H-Trp-Tyr-Lys-His-Val-Ala-Ser-Pro-Arg-Tyr-His-Thr-Val-Gly-Arg-Ala-Ala-Gly-Leu-Leu-Met-Gly-Leu-OH

Synonyms: NPW-23 (HUMAN);NEUROPEPTIDE W-23 (HUMAN);Neuropeptide W-23 (human) TFA;Neuropeptide W-23 (huMan) NPW-23 (huMan);Neuropeptide W-23(human),WYKHVASPRYHTVGRAAGL MGL,NPW-23, >95%;TRP-TYR-LYS-HIS-VAL-ALA-SER-PRO-ARG-TYR-HIS-THR-VAL-GLY-ARG-ALA-ALA-GLY-LEU-LEU-MET-GLY-LEU;H-Trp-Tyr-Lys-His-Val-Ala-Ser-Pro-Arg-Tyr-His-Thr-Val-Gly-Arg-Ala-Ala-Gly-Leu-Leu-Met-Gly-Leu-OH;Neuropeptide W23(human),hypetension,anorexigenic effect,Neuropeptide W 23(human),Neuropeptide W-23 (human),NPW 23,GPR7,Inhibitor,Neuropeptide W,GPR8,NPBW1,NPBW2,inhibit,NPW23;L-Leucine, L-tryptophyl-L-tyrosyl-L-lysyl-L-histidyl-L-valyl-L-alanyl-L-seryl-L-prolyl-L-arginyl-L-tyrosyl-L-histidyl-L-threonyl-L-valylglycyl-L-arginyl-L-alanyl-L-alanylglycyl-L-leucyl-L-leucyl-L-methionylglycyl-

CBNumber:: CB3154841

Molecular Formula:: C119H183N35O28S

Molecular Weight:: 2584.01

MDL Number:: MFCD26792553

MOL File:: 383415-79-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:51:44

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H-Trp-Tyr-Lys-His-Val-Ala-Ser-Pro-Arg-Tyr-His-Thr-Val-Gly-Arg-Ala-Ala-Gly-Leu-Leu-Met-Gly-Leu-OH Properties

storage temp.	Desiccate at -20°C
form	Solid
color	White to off-white
Water Solubility	Soluble to 1 mg/ml in sterile water

H-Trp-Tyr-Lys-His-Val-Ala-Ser-Pro-Arg-Tyr-His-Thr-Val-Gly-Arg-Ala-Ala-Gly-Leu-Leu-Met-Gly-Leu-OH price More Price(24)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	FN109647	Neuropeptide W-23 (human)	383415-79-0	0.5mg	$565.41	2026-06-04	Buy
Biosynth	FN109647	Neuropeptide W-23 (human)	383415-79-0	1mg	$980.04	2026-06-04	Buy
Biosynth	FN109647	Neuropeptide W-23 (human)	383415-79-0	2mg	$1884.7	2026-06-04	Buy
Biosynth	FN109647	Neuropeptide W-23 (human)	383415-79-0	5mg	$3392.45	2026-06-04	Buy
Biosynth	FN109647	Neuropeptide W-23 (human)	383415-79-0	10mg	$6596.4	2026-06-04	Buy

Product number	Packaging	Price	Buy
FN109647	0.5mg	$565.41	Buy
FN109647	1mg	$980.04	Buy
FN109647	2mg	$1884.7	Buy
FN109647	5mg	$3392.45	Buy
FN109647	10mg	$6596.4	Buy

H-Trp-Tyr-Lys-His-Val-Ala-Ser-Pro-Arg-Tyr-His-Thr-Val-Gly-Arg-Ala-Ala-Gly-Leu-Leu-Met-Gly-Leu-OH Chemical Properties, Uses, Production

Uses

Neuropeptide W-23 (human) (NPW-23), the active form of Neuropeptide W, is an endogenous agonist of NPBW1 (GPR7) and NPBW2 (GPR8)[1].

in vivo

Neuropeptide W-23 (human) (NPW-23) (0.3-3.0 nM; intracerebroventricular injection; 2 μL) increases total behavioral activity, including locomotion and grooming in conscious rats^[2].
Neuropeptide W-23 (human) (NPW-23) (2-8 nM; i.c.v.; 10 μL) shows anorexigenic effect in rats^[3].

Animal Model:	Male Harlan Sprague-Dawley rats, 250–300 g^[2]
Dosage:	0.3, 1.0 and 3.0 nM
Administration:	Intracerebroventricular injection, 2 μL
Result:	Caused significant increases in mean arterial pressure. Demonstrated a significant increase in total activity, ambulatory activity, and duration of stereotypy.

Animal Model:	Male Wistar rats weighing 250–300 g^[3]
Dosage:	2, 4, 6 and 8 nM
Administration:	Intra-cerebroventricular injection, 10 μL
Result:	Decreased dark feeding and fasting-induced feeding, decreased feeding intake and weight gain.

References

[1] Ji L, et al. Modulation of CaV1.2 calcium channel by neuropeptide W regulates vascular myogenic tone via G protein-coupled receptor 7. J Hypertens. 2015 Dec;33(12):2431-42. DOI:10.1097/HJH.0000000000000723
[2] Pate AT, et al. Neuropeptide W increases mean arterial pressure as a result of behavioral arousal. Am J Physiol Regul Integr Comp Physiol. 2013 Oct 1;305(7):R804-10. DOI:10.1152/ajpregu.00119.2013
[3] Naso T, et al. Central neuropeptide W has anorexigenic effect in rats. J Anim Physiol Anim Nutr (Berl). 2014 Apr;98(2):228-34. DOI:10.1111/jpn.12067

H-Trp-Tyr-Lys-His-Val-Ala-Ser-Pro-Arg-Tyr-His-Thr-Val-Gly-Arg-Ala-Ala-Gly-Leu-Leu-Met-Gly-Leu-OH Preparation Products And Raw materials

Raw materials

Preparation Products

H-Trp-Tyr-Lys-His-Val-Ala-Ser-Pro-Arg-Tyr-His-Thr-Val-Gly-Arg-Ala-Ala-Gly-Leu-Leu-Met-Gly-Leu-OH Suppliers

Global Suppliers ( 74)

Supplier	Tel	Email	Country	ProdList	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
Cellmano Biotech Limited	0551-65326643 18156095617	info@cellmano.com	China	1010	55
MedChemexpress LLC	021-58955995	sales@medchemexpress.cn	United States	4853	58
Creative Peptides		info@creative-peptides.com	United States	6083	56
Shanghai YuanYe Biotechnology Co., Ltd.	18916372613	yanzihan@shyuanye.com	China	87240	60
Nanjing Leon Biological Technology Co., Ltd.	025-84523390 -127; 17705183659	sales@njleonbiotech.com	China	5501	55
Nanjing Peptide Biotech Ltd.	025-58361106-805 15951641583	zhao.xu@njpeptide.com	China	9976	55
Chengdu Youngshe Chemical Co., Ltd.	+86-17380623303	Caroline@youngshechem.com	China	4731	58

Supplier	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	69
GL Biochem (Shanghai) Ltd	64
Chemsky（shanghai）International Co.,Ltd.	50
Cellmano Biotech Limited	55
MedChemexpress LLC	58
Creative Peptides	56
Shanghai YuanYe Biotechnology Co., Ltd.	60
Nanjing Leon Biological Technology Co., Ltd.	55
Nanjing Peptide Biotech Ltd.	55
Chengdu Youngshe Chemical Co., Ltd.	58

View Latest Price from H-Trp-Tyr-Lys-His-Val-Ala-Ser-Pro-Arg-Tyr-His-Thr-Val-Gly-Arg-Ala-Ala-Gly-Leu-Leu-Met-Gly-Leu-OH manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-07-15	Neuropeptide W-23(human) 383415-79-0	$123.00-538.00		98.50%	10g	TargetMol Chemicals Inc.

Neuropeptide W-23(human)
383415-79-0
$123.00-538.00
98.50%
TargetMol Chemicals Inc.

383415-79-0 (H-Trp-Tyr-Lys-His-Val-Ala-Ser-Pro-Arg-Tyr-His-Thr-Val-Gly-Arg-Ala-Ala-Gly-Leu-Leu-Met-Gly-Leu-OH) Related Search:

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Neuropeptide W-23(human),WYKHVASPRYHTVGRAAGL MGL,NPW-23, >95% NPW-23 (HUMAN) NEUROPEPTIDE W-23 (HUMAN) TRP-TYR-LYS-HIS-VAL-ALA-SER-PRO-ARG-TYR-HIS-THR-VAL-GLY-ARG-ALA-ALA-GLY-LEU-LEU-MET-GLY-LEU Neuropeptide W-23 (huMan) NPW-23 (huMan) L-Leucine, L-tryptophyl-L-tyrosyl-L-lysyl-L-histidyl-L-valyl-L-alanyl-L-seryl-L-prolyl-L-arginyl-L-tyrosyl-L-histidyl-L-threonyl-L-valylglycyl-L-arginyl-L-alanyl-L-alanylglycyl-L-leucyl-L-leucyl-L-methionylglycyl- Neuropeptide W23(human),hypetension,anorexigenic effect,Neuropeptide W 23(human),Neuropeptide W-23 (human),NPW 23,GPR7,Inhibitor,Neuropeptide W,GPR8,NPBW1,NPBW2,inhibit,NPW23 Neuropeptide W-23 (human) TFA H-Trp-Tyr-Lys-His-Val-Ala-Ser-Pro-Arg-Tyr-His-Thr-Val-Gly-Arg-Ala-Ala-Gly-Leu-Leu-Met-Gly-Leu-OH 383415-79-0 C119H183N35O28S Various peptides