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(S)-(-)-2-Chloropropionic acid

(S)-(-)-2-Chloropropionic acid Structure
(S)-(-)-2-Chloropropionic acid structure
CAS No.
29617-66-1
Chemical Name:
(S)-(-)-2-Chloropropionic acid
Synonyms
2-CHLOROPROPANOIC ACID;(2S)-2-Chloropropanoic acid;L-CPA;L-α-Chloropropionic acid;)-2-Chlo;(S)-()-2-Chlo;(s)-propanoicaci;L-2-CHLOROPROPINONICAL;S-(-)-2-Chloropropanoic;S-2-Chlorpropionic acid
CBNumber:
CB3161267
Molecular Formula:
C3H5ClO2
Molecular Weight:
108.52
MDL Number:
MFCD00064205
MOL File:
29617-66-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 01:00:43
Product description Number Pack Size Price
(S)-(-)-2-Chloropropionic Acid >98.0%(GC)(T) C1373 1g $17
(S)-(-)-2-Chloropropionic Acid >98.0%(GC)(T) C1373 5g $29
(S)-(-)-2-Chloropropionic Acid TRC-C379700-5G 5g $84
(S)-(-)-2-Chloropropionic Acid TRC-C379700-2G 2g $64
(S)-(-)-2-Chloropropionic Acid TRC-C379700-1G 1g $59
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(S)-(-)-2-Chloropropionic acid Properties

Melting point 4 °C
Boiling point 77 °C/10 mmHg (lit.)
alpha -14.5 º (c=neat)
Density 1.249 g/mL at 25 °C (lit.)
vapor pressure 5hPa at 20℃
refractive index n20/D 1.436
Flash point 140 °F
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
pka 2.83(at 25℃)
form Liquid
color Clear light yellow
optical activity [α]25/D -14°, neat
Water Solubility soluble
BRN 1720257
InChI 1S/C3H5ClO2/c1-2(4)3(5)6/h2H,1H3,(H,5,6)/t2-/m0/s1
InChIKey GAWAYYRQGQZKCR-REOHCLBHSA-N
SMILES C[C@H](Cl)C(O)=O
LogP 0.82 at 20.5℃
CAS DataBase Reference 29617-66-1(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII PCC7J322CM
NIST Chemistry Reference (S)-(-)-2-chloropropionic acid(29617-66-1)
UNSPSC Code 12352101

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS05,GHS07,GHS08
Signal word  Danger
Hazard statements  H312-H318-H302+H312-H314-H373-H290-H302
Precautionary statements  P260h-P301+P330+P331-P303+P361+P353-P501a-P234-P260-P264-P270-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P390-P405-P406-P501-P280-P305+P351+P338-P310
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  C
Risk Statements  21/22-35-48/22
Safety Statements  23-26-28-36/37/39-45
RIDADR  UN 2511 8/PG 3
WGK Germany  1
RTECS  UA2451950
HazardClass  8
PackingGroup  III
HS Code  29159080
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Oral
Eye Dam. 1
Skin Corr. 1A
STOT RE 2
REACH Registrations Active
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
0
3 0

(S)-(-)-2-Chloropropionic acid price More Price(61)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C1373 (S)-(-)-2-Chloropropionic Acid >98.0%(GC)(T) 29617-66-1 1g $17 2026-04-30 Buy
TCI Chemical C1373 (S)-(-)-2-Chloropropionic Acid >98.0%(GC)(T) 29617-66-1 5g $29 2026-04-30 Buy
TRC TRC-C379700-5G (S)-(-)-2-Chloropropionic Acid 29617-66-1 5g $84 2026-06-03 Buy
TRC TRC-C379700-2G (S)-(-)-2-Chloropropionic Acid 29617-66-1 2g $64 2026-06-03 Buy
TRC TRC-C379700-1G (S)-(-)-2-Chloropropionic Acid 29617-66-1 1g $59 2026-06-03 Buy
Product number Packaging Price Buy
C1373 1g $17 Buy
C1373 5g $29 Buy
TRC-C379700-5G 5g $84 Buy
TRC-C379700-2G 2g $64 Buy
TRC-C379700-1G 1g $59 Buy

(S)-(-)-2-Chloropropionic acid Chemical Properties,Uses,Production

Description

(S)-2-chloropropanoic acid is a monocarboxylic acid that is propanoic acid substituted at position 2 by a chloro group (the S-enantiomer). It has a role as a neurotoxin. It is a monocarboxylic acid and a chlorocarboxylic acid. It is functionally related to propionic acid. It is a conjugate acid of a (S)-2-chloropropanoate.

Chemical Properties

Colourless Oil

Uses

Through the stereo displacement of (S)-(-)-2-Chloropropionic acid PPAR Agonist can be synthesized via asymmetric hydrogenation of a cinnamic acid derivative.

Definition

ChEBI: A monocarboxylic acid that is propanoic acid substitued at position 2 by a chloro group (the S-enantiomer).

General Description

2-Chloropropionic acid is an essential raw material for synthesising pesticides, dyes and medicines. Its application involves many sectors of the national economy and people's daily lives. It is an essential fine chemical product. In particular, (S)-(-)-2-Chloropropionic acid is a crucial intermediate for synthesising highly efficient and low-toxic aromatic oxygen propionic acid herbicides. For example, it can be used to synthesize (R)-2-(4-hydroxyphenoxy) propionic acid (ester) intermediates, fenthionyl, fenthionyl, fenthionyl, etc. At present, the preparation methods of (S)-(-)-2-chloropropionic acid and (R)-(+)-2-chloropropionic acid include: (1) chemical resolution method; (2) bioenzymatic resolution method; (3) chromatographic resolution method; (4) asymmetric synthesis method, etc.

Flammability and Explosibility

Non flammable

Synthesis

JP 061172846 provides a method for resolving racemic 2-chloropropionic acid using an optically active 2-aryl-2-isopropylethylamine as a resolving agent to obtain (S)-(-)-2-Chloropropionic acid (yield 24.2% and enantiomeric excess 83.2%). DE 4328231 provides a method for catalyzing the hydrolysis of 2-chloropropionic acid esters by a hydrolase (Pseudomonas Lipase) to hydrolyze (S)-2-chloropropionic acid esters to generate (S)-(-)-2-Chloropropionic acid.

Purification Methods

Purify the acid by fractionating twice through a 115cm Podbielniak column (p 11, calculated 50 theoretical plates at atmospheric pressure) using a take-off ratio of 1:5. The acid chloride is prepared by dissolving the acid in SOCl2, adding a few drops of PCl3, refluxing and then distilling through a 30cm column, b 53o/100mm, [] -4.6o (neat), d 1.2689, n1.4368. [Fu et al. J Am Chem Soc 76 6954 1954, Beilstein 2 IV 745.]

(S)-(-)-2-Chloropropionic acid synthesis

56-41-7
29617-66-1
Synthesis of (S)-(-)-2-Chloropropionic acid from L-Alanine

(S)-(-)-2-Chloropropionic acid Preparation Products And Raw materials

Raw materials

Propanal, 2-chloro-, (2R)- (9CI) (R)-(+)-2-Chloropropionic acid Methyl 2-chloropropionate

Preparation Products

(R)-(+)-2-BENZYLOXYPROPIONIC ACID

(S)-(-)-2-Chloropropionic acid Suppliers

Global( 359)Suppliers
Supplier Tel Email Country ProdList Advantage
shandong exelon biochem co.ld
+86-533-2119995 +8615053330977 451614802@QQ.com China 96 58
JiangXi Bobert Imp&Exp Co.,LTD
+8618071643627 rze2024@163.com China 226 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8738 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 21157 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-86-13131129325 +8613131129325 sales1@chuanghaibio.com China 5228 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20122 58
Springchem New Material Technology Co.,Limited 		+86-021-62885108 +8613917661608 info@spring-chem.com China 2068 57
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29640 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21587 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
Supplier Advantage
shandong exelon biochem co.ld
58
JiangXi Bobert Imp&Exp Co.,LTD
58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Dideu Industries Group Limited 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Henan Fengda Chemical Co., Ltd 		58
Springchem New Material Technology Co.,Limited 		57
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
career henan chemical co 		58

View Lastest Price from (S)-(-)-2-Chloropropionic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-(-)-2-Chloropropionic acid pictures 2026-05-28 (S)-(-)-2-Chloropropionic acid
29617-66-1
 $50.60 1KG 98% 5000kg Hebei Chuanghai Biotechnology Co,.LTD
(S)-(-)-2-Chloropropionic acid pictures 2026-03-20 (S)-(-)-2-Chloropropionic acid
29617-66-1
 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
S-(-)-2-Chloropropionic Acid pictures 2026-01-29 S-(-)-2-Chloropropionic Acid
29617-66-1
 10kg 99%min 10 tons Hangzhou Verychem Science And Technology Co.Ltd

(S)-(-)-2-Chloropropionic acid Spectrum

(S)-(-)-2-Chloropropionic acid(29617-66-1)1HNMR(S)-(-)-2-Chloropropionic acid(29617-66-1)Raman(S)-(-)-2-Chloropropionic acid(29617-66-1)FT-IR(S)-(-)-2-Chloropropionic acid(29617-66-1)IR

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PROPANOIC ACID, 2-CHLORO-, (2S)- (S)-(-)-2-CHLOROPROPIONIC ACID (S)-2-CHLOROPROPIONIC ACID (S)-(-)-2-CHLOROPROPIONOIC ACID (S)-(-)-2-CHLOROPROPANOIC ACID (2s)-chloropropanoicacid L-α-Chloropropionic acid L-(-)-2-Chloro Proxic Acid L-2-CHLOROPROPINONICAL S-(-)-2-Chloropropanoic (S)-(-)-2-CHLOROPROPIONIC ACID 98% OPTICAL95% (S)-(-)-2-Chloropropionic acid, ChiPros(tm 98%, ee 96+% (S)-(-)-2-Chloropropanoic acid, L-α-Chloropropionic acid (S)-()-2-Chloropropionic acid,(S)-()-2-Chloropropanoic acid, L-α-Chloropropionic acid )-2-Chlo (2S)-2-Chloropropionic acid (S)-2-Chloropropionic Acid,99%e.e. (S)-()-2-Chlo (S)-a-chloropropionic acid (S)-(-)-2-Chloropropionic acid, 98% 500MG (S)-(-)-2-Chloropropionic acid,98% (S)-(-)-2-Chloropropionic acid 99% S-2-Chlorpropionic acid S(-) 2-Chloropropionic acid (LCPA) (s)-propanoicaci 2(s)-chloropropionicacid 2-chloro-,(2S)-Propanoicacid alpha-l-chloropropionicacid l-2-chloropropanoicacid l-2-chloropropionicacid L-ALPHA-CHLOROPROPIONIC ACID L-(A)-CHLOROPROPIONIC ACID (S)-(-)-2-Chloropropionic Acid > (S)-α-chloropropionic acid (S)-2-Chloropropanoicaci (-)-2-Chloropropanoic acid S-2-Chloropropionic Acid pure, 98% (S)-(?)-2-Chloropropionic acid (2S)-2-Chloropropanoic acid 2-CHLOROPROPANOIC ACID L-CPA 29617-66-1 598-79-7 C3H5ClO2 Asymmetric Synthesis Carboxylic Acids Chiral Building Blocks Chiral Compounds (Building Blocks for Liquid Crystals) Building Blocks for Liquid Crystals Carboxylic Acids (Chiral) Organic Building Blocks Heterocycle-Pyridine series Miscellaneous Reagents Building Blocks for Liquid Crystals Carboxylic Acids (Chiral) Chiral Building Blocks Chiral Compounds (Building Blocks for Liquid Crystals) Functional Materials