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PROPERICYAZINE

CAS No.
2622-26-6
Chemical Name:
PROPERICYAZINE
Synonyms
Periciazine;ic6002;rp8908;wh7508;6909rp;Aolept;IC 6002;RP 8908;RP 8909;WH 7508
CBNumber:
CB3162774
Molecular Formula:
C21H23N3OS
Molecular Weight:
365.49
MDL Number:
MFCD00210348
MOL File:
2622-26-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
Product description Number Pack Size Price
Periciazine ≥98% 33149 1mg $36
Periciazine ≥98% 33149 5mg $128
Periciazine ≥98% 33149 10mg $219
Periciazine ≥98% 33149 25mg $378
Pericyazine >95%(HPLC) TRC-P287360-25MG 25mg $300
More product size

PROPERICYAZINE Properties

Melting point 116-117°
Boiling point 593.4±50.0 °C(Predicted)
Density 1.1198 (rough estimate)
refractive index 1.6740 (estimate)
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 14.87±0.20(Predicted)
color Light Yellow to Yellow
Water Solubility 38.01mg/L(37 ºC)
CAS DataBase Reference 2622-26-6
FDA UNII 3405M6FD73
ATC code N05AC01

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501
Hazard Codes  Xn
Risk Statements  22-36/37/38-20/21/22
Safety Statements  26-36
RTECS  SN7175000
Toxicity LD50 orally in rats: 395 mg/kg (Schafer)
NFPA 704
0
3 0

PROPERICYAZINE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 33149 Periciazine ≥98% 2622-26-6 1mg $36 2026-04-30 Buy
Cayman Chemical 33149 Periciazine ≥98% 2622-26-6 5mg $128 2026-04-30 Buy
Cayman Chemical 33149 Periciazine ≥98% 2622-26-6 10mg $219 2026-04-30 Buy
Cayman Chemical 33149 Periciazine ≥98% 2622-26-6 25mg $378 2026-04-30 Buy
TRC TRC-P287360-25MG Pericyazine >95%(HPLC) 2622-26-6 25mg $300 2026-06-03 Buy
Product number Packaging Price Buy
33149 1mg $36 Buy
33149 5mg $128 Buy
33149 10mg $219 Buy
33149 25mg $378 Buy
TRC-P287360-25MG 25mg $300 Buy

PROPERICYAZINE Chemical Properties,Uses,Production

Chemical Properties

Yellow Solid

Originator

Aolept, Bayer Vital

Uses

Psychotherapeutic phenothiazine. Antipsychotic.

Uses

Spectrophotometric reagent for palladium and ruthenium.

Definition

ChEBI: A member of the class of phenothiazines that is 10H-phenothiazine substituted by a 3-(4-hydroxypiperidin-1-yl)propyl group at the nitrogen atom and a carbonitrile group at position 2. Periciazine is a first generation antipsychotic.

Manufacturing Process

2-Cyano-10-(3-methanesulfonyloxypropyl)phenthiazine and 4hydroxypiperidine in toluene were heated under reflux with stirring. The reaction mixture was allowed to cool and water was added. The resulting toluene solution layer was decanted and washed twice with water. The toluene solution was then stirred with 5% hydrochloric acid. The hydrochloride of the desired phenthiazine base precipitated in gummy condition in the aqueous layer. This was decanted and treated with sodium hydroxide (density 1.33). It was then extracted three times with ethyl acetate. The extracts were dried over sodium sulfate, filtered and concentrated in vacuum. A resinous product was obtained. This product was dissolved in a mixture of benzene and cyclohexane and chromatographed on a column containing alumina. The chromatographed product was eluted successively with mixtures of benzene and cyclohexane and then with benzene and finally with a mixture of benzene and ethyl acetate. The eluates were evaporated to yield a crude product. This product was recrystallised from aqueous ethanol (40% water) and yielded 2cyano-10-[3-(4-hydroxy-1-piperidyl)propyl]phenthiazine as white crystals.

Therapeutic Function

Neuroleptic

Safety Profile

Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. Used as an antipsychotic agent. When heated to decomposition it emits very toxic fumes of CN-, NOx, and SOx. See also NITRILES.

Purification Methods

It recrystallises from a saturated solution in cyclohexane. It is antipsychotic and is a sensitive reagent for Pd, Va, Ru, Rh and Au. [Gowda et al. Anal Chem 55 1816 1983, Anal Chim Acta 154 347 1983, Beilstein 27 III/IV 4110.]

PROPERICYAZINE Preparation Products And Raw materials

Global( 81)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
AFINE CHEMICALS LIMITED
+86-571-85134551 +86-18958018566 info@afinechem.com China 15058 58
Finetech Industry Limited
+86-27-8746-5837 +86-18627785180 info@finetechnology-ind.com China 9539 58
BOC Sciences
16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 17705817739 info@dycnchem.com China 52693 58
Shaanxi Didu New Materials Co. Ltd
+86-86-17392712779 +86-13289823923 1090@dideu.com China 8651 58
GIHI CHEMICALS CO.,LIMITED
+86-571-86217390; +8618058761490 info@gihichemicals.com China 49859 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+86-18621343501 product@acmec-e.com China 33301 58
Aladdin Scientific
tp@aladdinsci.com United States 50108 58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580 cooperation@kean-chem.com China 40048 58

View Lastest Price from PROPERICYAZINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pericyazine pictures 2026-07-27 Pericyazine
2622-26-6
$85.00-247.00 99.61% 10g TargetMol Chemicals Inc.
  • Pericyazine pictures
  • Pericyazine
    2622-26-6
  • $85.00-247.00
  • 99.61%
  • TargetMol Chemicals Inc.
PROPERICIAZINE PROPERICYAZINE 1-(3-(2-cyano-10-phenothiazinyl)propyl)-4-piperidino f.i.6145 IC 6002 ic6002 Nelactil Nemactil Neulactil Neuleptil Periciazinum pericyazine Phenothiazine-2-carbonitrile, 10-[3-(4-hydroxypiperidino)propyl]- Piperocyanomazine RP 8908 RP 8909 rp8908 SKF 20,716 skf20,716 WH 7508 wh7508 10-(3-(4-hydroxypiperidino)propyl)-phenothiazine-2-carbonitril 10-(3-(4-Hydroxypiperidino)propyl)phenothiazine-2-carbonitrile 10-[3-(4-Hydroxy-1-piperidinyl)propyl]-10H-phenothiazine-2-carbonitrile 10H-Phenothiazine-2-carbonitrile, 10-[3-(4-hydroxy-1-piperidinyl)propyl]- 2-Cyano-10-(3-(4-hydroxy-1-piperidyl)propyl)phenothiazine 2-Cyano-10-(3-(4-hydroxypiperidino)propyl)phenothiazine 4-Piperidinol, 1-(3-(2-cyano-10-phenothiazinyl)propyl)- 6909 RP 6909rp Aolept Bayer 1409 bayer1409 Cyano-3 ((hydroxy-4 piperidyl-1)-3 propyl)-10 phenothiazine cyano-3((hydroxy-4piperidyl-1)-3propyl)-10phenothiazine F.I. 6145 10-(3-(4-Hydroxypiperidin-1-yl)propyl)-10H-phenothiazine-2-carbonitrile Properazine 2.4.5-Trichlorophenylacetate 1g [2622-26-6] 10-[3-(4-Hydroxy-1-piperidinyl)propyl]- Properciazine 4,6-dibromo-2,2-dimethyl-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxole Propericiazine (Periciazine) Periciazine oxalate salt RP8909,antipsychotic,Dopamine Receptor,Pericyazine,psychosis,adrenolytic,anxiety,anticholinergic,RP-8909,inhibit,Inhibitor,extrapyramidal Pericyazine, 10 mM in DMSO Periciazine 2622-26-6 Amines Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds AOLEPT